Receptor News and Research

RSS

Study provides insights into pain signaling mechanism in the brain

Fast communication between our brain cells - or neurotransmission as it is called - is hugely important for our brain to work properly. Some of the messengers involved in this form of communication are neuropeptides, which are chemicals produced in the brain.

31 Mar 2020

Novel immunotherapy eradicates solid tumors in mice without adverse side effects

Scientists have developed a new immunotherapy that eradicates solid tumors in mice without adverse side effects, according to a new study published today in eLife.

31 Mar 2020

Two newer types of diabetes medications show heart and kidney benefits

Two newer types of medications commonly used to treat type 2 diabetes are similar in their ability to reduce major heart complications, including heart attack, stroke and death from cardiovascular disease, according to research accepted for presentation at ENDO 2020, the Endocrine Society's annual meeting, and publication in a special supplemental section of the Journal of the Endocrine Society.

31 Mar 2020

New viable therapeutic strategy found for ER+ breast cancer

Researchers say they have found a viable new therapeutic strategy for estrogen receptor-positive (ER+) breast cancer, even cancers that are resistant to current standard of care treatments.

31 Mar 2020

Potential new method of breast cancer treatment using androgen receptor

Scientists may have discovered a new therapeutic approach to treat ER+ breast cancer using androgen receptor-stimulating drugs.

31 Mar 2020

Evinacumab drug reduces cholesterol levels in patients with rare cholesterol disorder

The investigational drug evinacumab reduced low-density lipoprotein (LDL) cholesterol to near-normal levels among patients with a rare cholesterol disorder, meeting the primary endpoint in the first randomized placebo-controlled trial of the drug, which is being presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology (ACC.20/WCC).

31 Mar 2020

Clopidogrel added to aspirin and rvaroxaban shows no additional benefit for peripheral artery disease

The results of VOYAGER PAD found that people with peripheral artery disease (PAD) who took the blood thinner rivaroxaban with aspirin after undergoing lower extremity revascularization--a procedure to treat blocked arteries in the leg--had a significant reduction in the risk of major adverse limb and cardiovascular events when compared with those receiving aspirin alone.

31 Mar 2020

First-of-its-kind trial identifies a viable target for treating anhedonia

A first-of-its-kind trial has demonstrated that a receptor involved in the brain's reward system may be a viable target for treating anhedonia (or lack of pleasure), a key symptom of several mood and anxiety disorders.

31 Mar 2020

UDCA treatment affects C. diff life cycle, reduces inflammatory response in mice

Researchers from North Carolina State University have found that a commonly used drug made from secondary bile acids can affect the life cycle of Clostridioides difficile (C. diff) in vitro and reduce the inflammatory response to C. diff in mice.

30 Mar 2020

TWILIGHT trial: Brilinta reduces bleeding compared to dual therapy in high-risk coronary patients

Results from two subgroup analyses of the Phase IV independent TWILIGHT trial funded by AstraZeneca showed Brilinta (ticagrelor) monotherapy reduced the risk of clinically relevant bleeding over 12 months compared to aspirin plus Brilinta in high-risk coronary patients.

From AstraZeneca 30 Mar 2020

Investigational drug vericiguat benefits patients with worsening heart failure

Patients with worsening heart failure and reduced ejection fraction who received the investigational drug vericiguat had a significantly lower rate of cardiovascular death or heart failure hospitalization compared with those receiving a placebo, based on research presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology.

30 Mar 2020

Low-dose rivaroxaban reduces adverse heart events in symptomatic PAD post-intervention

People with symptomatic peripheral artery disease who took the blood thinner rivaroxaban with aspirin after undergoing a procedure to treat blocked arteries in the leg (lower extremity revascularization) had a 15% reduction in the risk of major adverse limb and cardiovascular events when compared with those receiving aspirin alone, according to research presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology.

30 Mar 2020

Zebrafish can provide genetic clues to human nicotine addiction

Researchers at Queen Mary University of London have shown that zebrafish can provide genetic clues to smoking, a complex human behavior.

30 Mar 2020

COVID-19 and its effects on the cardiovascular system

Researcher have reviewed the evidence showing the effects of the SARS-CoV-2 or novel coronavirus infection (COVID-19) on the cardiovascular system. Their study titled, “Potential Effects of Coronaviruses on the Cardiovascular System: A Review,” was published in the latest issue of JAMA Cardiology.

29 Mar 2020

Receptor News and Research

Study provides insights into pain signaling mechanism in the brain

Novel immunotherapy eradicates solid tumors in mice without adverse side effects

Two newer types of diabetes medications show heart and kidney benefits

New viable therapeutic strategy found for ER+ breast cancer

Potential new method of breast cancer treatment using androgen receptor

Evinacumab drug reduces cholesterol levels in patients with rare cholesterol disorder

Clopidogrel added to aspirin and rvaroxaban shows no additional benefit for peripheral artery disease

First-of-its-kind trial identifies a viable target for treating anhedonia

UDCA treatment affects C. diff life cycle, reduces inflammatory response in mice

TWILIGHT trial: Brilinta reduces bleeding compared to dual therapy in high-risk coronary patients

Investigational drug vericiguat benefits patients with worsening heart failure

Low-dose rivaroxaban reduces adverse heart events in symptomatic PAD post-intervention

Zebrafish can provide genetic clues to human nicotine addiction

COVID-19 and its effects on the cardiovascular system

Research characterizes iPS87 cell line as cancer-inducing, stem cell-like cell line

Heart and kidney patients should keep taking their medicines during COVID-19 pandemic

UC Davis launches two clinical trials to evaluate treatments for COVID-19

Maintaining VDR levels in pancreatic cells could protect against diabetes

A quest to unlock the genetic code of SARS-CoV-2

Study suggests potential therapeutic strategy against diabetes

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News