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New algorithm to reduce radiation dose in CT imaging

In recent years, advances in CT scanner technology have made perfusion computed tomography (CT) imaging an important diagnostic tool for patients with suspected stroke. Now, researchers at Mayo Clinic are working to reduce radiation dosages used to acquire perfusion and other CT images. Mayo Clinic medical physicist Cynthia McCollough, Ph.D., and her group of researchers presented their findings related to CT dose reduction at the 52nd Annual Meeting of the American Association of Physicists in Medicine on July 20 in Philadelphia. The presentation was entitled "20-Fold Dose Reduction Using a Gradient Adaptive Bilateral Filter: Demonstration Using in Vivo Animal Perfusion CT."

4 Aug 2010

Premier international conference to discuss latest diagnostic tools, emerging therapies for personalized medicine

What As scientists understand more about a tumor's underlying biology, personalized medicine is emerging as the new patient management paradigm. This year, the American Association for Cancer Research will host its fourth Molecular Diagnostics in Cancer Therapeutic Development: Challenges and Horizons conference at the Sheraton Denver Downtown Hotel in Denver, Colo. This meeting regularly draws representatives from academia and industry to discuss the latest in diagnostic tools and emerging therapies.

4 Aug 2010

International conference to discuss research, unresolved issues of sickle cell disease

Carlton Haywood Jr., Ph.D., an associate faculty member of the Johns Hopkins Berman Institute of Bioethics, will mark the 100-year anniversary of the discovery of sickle cell anemia on Wednesday, Aug. 4, with a talk on the impact that race has had on the history of research and treatment of the inherited blood disorder.

4 Aug 2010

Smokers are 11 times more likely to develop subareolar abscess

Women who smoke or pierce their nipples are more likely to develop a breast abscess, according to a new study in the July issue of the Journal of the American College of Surgeons. Researchers at the University of Iowa found the odds of developing primary breast abscess were six times higher in smokers than in nonsmokers, and smokers were 11 times more likely to develop subareolar abscess. Breast abscesses were 15 times more likely to recur in smokers than in nonsmokers. In addition, this study is one of the first to provide clinical evidence that nipple piercing is also a risk factor for subareolar breast abscess, with the onset of abscess occurring from one month to seven years from the time of piercing.

4 Aug 2010

Hospitals, docs adopting health IT ahead of schedule

Clinics and hospitals are increasingly switching to electronic medical records as a federal push to spread the technology sweeps across the nation.

4 Aug 2010

BCM collaborates with Roche NimbleGen for high throughput exome capture technology

The Baylor College of Medicine Human Genome Sequencing Center has standardized its target enrichment human disease research studies on Roche NimbleGen Sequence Capture Exome technology. The Baylor HGSC will sequence over 5,000 exomes in the next two years to identify genetic variants underlying multiple human diseases and will employ NimbleGen SeqCap EZ Exome and customized NimbleGen exome designs as the exome capture technology of choice. More than 15 different diseases will be investigated by Baylor HGSC, including brain, liver, pancreatic, colon, ovarian and bladder cancers, heart disease, diabetes, autism, and other inherited diseases with the goal of better understanding causative mutations and their impact on these diseases.

4 Aug 2010

Dendreon second-quarter revenue increases to $2.8 million

Dendreon Corporation today reported results for the quarter ended June 30, 2010. Revenue for the quarter ended June 30, 2010 was $2.8 million compared to $25,000 for the quarter ended June 30, 2009. Revenue for the six months ended June 30, 2010 was $2.8 million compared to $55,000 for the six months ended June 30, 2009.

4 Aug 2010

Study to understand processes that lead to onset of testicular germ cell cancer

Scientists have developed a model that will enable them to investigate, for the first time, how human testes develop in baby boys while they are in the womb. Until now it has been impossible to study testicular development during pregnancy in humans and this discovery will enable researchers to understand the processes that can lead to the onset of testicular germ cell cancer (TGCC) in young adult life, and how factors, such as common environmental chemicals, might play a role.

4 Aug 2010

Arena reports lower net loss of $28.80M for second-quarter 2010

Arena Pharmaceuticals, Inc. today reported financial results for the second quarter ended June 30, 2010, and recent developments, including the successful Pre-Approval Inspection, or PAI, of the company's Swiss drug product manufacturing facility by the US Food and Drug Administration, or FDA.

4 Aug 2010

Today's OpEds: WSJ on Virginia court ruling; Health law politics; For-profit insurers; Mass. doc shortage; Physician errors

All the smart people in the political, media and legal classes know that ObamaCare is constitutional and anyone who says otherwise is frivolous. This faux consensus, however, does not include a U.S. district court judge in Virginia, who yesterday rejected the Administration's argument that one of the key constitutional challenges should be dismissed outright. Now the case will proceed to arguments on the merits this fall (8/3).

4 Aug 2010

Excaliard reports positive results from EXC 001 Phase 2 clinical trial for reducing scar severity

Excaliard Pharmaceuticals, Inc., today announced positive results from its Phase 2 clinical trial of EXC 001, a new chemical entity for reducing fibrosis. Results showed that EXC 001 treatment significantly reduced scar severity in subjects undergoing an elective abdominoplasty compared to placebo.

4 Aug 2010

One-on-one talk with therapist reduces peer aggression

A brief, motivational talk in the emergency room reduced by half the chances that teenagers would experience peer violence or problems due to drinking, according to a study published Aug. 4 in a theme issue of the Journal of the American Medical Association.

4 Aug 2010

CSI launches Diamondback Predator 360 catheter system for treatment of peripheral arterial disease

Cardiovascular Systems, Inc. has launched its second-generation product, the Diamondback Predator 360° PAD System, for the treatment of peripheral arterial disease (PAD). The new device uses the same mechanism of action as the clinically proven Diamondback 360 PAD System with improvements in the crowns and shaft for enhanced clinical performance and shorter procedure times.

4 Aug 2010

Master model to track mercury movement from original emission source to humans

University of Louisville Public Health doctoral student Caroline Chan is working to create scientific tools to help environmental policy decision makers evaluate and modify mercury emission regulations.

3 Aug 2010

POZEN reports $16.2M net income for second-quarter 2010

POZEN Inc., a pharmaceutical company committed to transforming medicine that transforms lives, today announced results for the second quarter ended June 30, 2010.

3 Aug 2010

Caliper Life Sciences second-quarter GAAP revenue decreases 10% to $29.0 million

Caliper Life Sciences, Inc., today reported results for its second quarter ended June 30, 2010. Second quarter GAAP revenue decreased 10% to $29.0 million from $32.1 million in the same period in 2009 as a result of divestitures in 2010 and 2009. Revenue from on-going business increased 4% on a reported basis and 6% on an organic basis (which assumes constant currency).

3 Aug 2010

Investigators explore legal, ethical permissibility of carrying out request specific to VAD

Patients have the right to refuse or request the withdrawal of any unwanted treatment. In an article published in the online issue of Mayo Clinic Proceedings, investigators explore the legal and ethical permissibility of carrying out such a request specific to a ventricular assist device.

3 Aug 2010

MEDNAX second-quarter revenue increases 9% to $349.1 million

MEDNAX, Inc. today reported earnings per share of $1.04 for the three months ended June 30, 2010, that were driven by contributions resulting from the Company's acquisitions and ongoing operating efficiencies.

3 Aug 2010

Insulin resistance from obesity leads to lower cognitive performance in children: Research

A study by researchers at NYU Langone Medical Center have found that obese adolescents with type 2 diabetes have diminished cognitive performance and subtle abnormalities in the brain as detected by Magnetic Resonance Imaging (MRI). Identification of cognitive impairments as a complication of type 2 diabetes emphasizes the importance of addressing issues of inactivity and obesity, two important risk factors for the development of the disease among the young.

3 Aug 2010

Obesity-related Quality-Adjusted Life Years lost by U.S. adults doubles from 1993 to 2008

Although the prevalence of obesity and obesity-attributable deaths has steadily increased, the resultant burden of disease associated with obesity has not been well understood. A new study published in the September issue of the American Journal of Preventive Medicine indicates that Quality-Adjusted Life Years (QALYs) lost to U.S. adults due to morbidity and mortality from obesity have more than doubled from 1993-2008 and the prevalence of obesity has increased 89.9% during the same period.

3 Aug 2010

Medicine News and Research

New algorithm to reduce radiation dose in CT imaging

Premier international conference to discuss latest diagnostic tools, emerging therapies for personalized medicine

International conference to discuss research, unresolved issues of sickle cell disease

Smokers are 11 times more likely to develop subareolar abscess

Hospitals, docs adopting health IT ahead of schedule

BCM collaborates with Roche NimbleGen for high throughput exome capture technology

Dendreon second-quarter revenue increases to $2.8 million

Study to understand processes that lead to onset of testicular germ cell cancer

Arena reports lower net loss of $28.80M for second-quarter 2010

Today's OpEds: WSJ on Virginia court ruling; Health law politics; For-profit insurers; Mass. doc shortage; Physician errors

Excaliard reports positive results from EXC 001 Phase 2 clinical trial for reducing scar severity

One-on-one talk with therapist reduces peer aggression

CSI launches Diamondback Predator 360 catheter system for treatment of peripheral arterial disease

Master model to track mercury movement from original emission source to humans

POZEN reports $16.2M net income for second-quarter 2010

Caliper Life Sciences second-quarter GAAP revenue decreases 10% to $29.0 million

Investigators explore legal, ethical permissibility of carrying out request specific to VAD

MEDNAX second-quarter revenue increases 9% to $349.1 million

Insulin resistance from obesity leads to lower cognitive performance in children: Research

Obesity-related Quality-Adjusted Life Years lost by U.S. adults doubles from 1993 to 2008

Everything there is to know about biosimilars eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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