Clinical Trial News and Research

RSS

Common acne medication can slow progress of relapsing-remitting MS, trial shows

A Canadian clinical trial led by researchers at the University of Calgary's Hotchkiss Brain Institute, at the Cumming School of Medicine, shows that minocycline, a common acne medication, can slow the progress of relapsing-remitting multiple sclerosis (MS) in people who have recently experienced their first symptoms.

1 Jun 2017

Experimental drug increases progression-free survival in pancreatic cancer patients, clinical trial shows

By adding an experimental drug to a standard chemotherapy regimen, a subset of patients with metastatic pancreatic cancer had a significantly longer period before the cancer progressed as compared with those who received the standard treatment, according to a Phase 2 clinical trial led by an investigator at Fred Hutchinson Cancer Research Center.

1 Jun 2017

Phase 2 clinical study examines Alzheimer's disease drug to treat adults with Down syndrome

A phase 2 clinical trial in young adults with Down syndrome of a drug being investigated for the treatment of Alzheimer's disease supports further investigation of its potential.

1 Jun 2017

Moffitt researchers hope to improve personalized radiation therapy for head and neck cancer patients

Radiation therapy is one of the most common treatments used to fight cancer, with an estimated 500,000 people each year receiving radiation therapy either alone or in combination with other treatments.

31 May 2017

Clinical trial uses small molecule to treat men with incurable prostate cancer

NewYork-Presbyterian and Weill Cornell Medicine have begun the first clinical trial in the United States that uses a small molecule to treat men with progressive prostate cancer that has spread beyond the prostate and is no longer responding to hormonal therapy.

31 May 2017

Study finds parent-based obesity treatment without their children could be used to tackle childhood obesity

Childhood obesity is connected with negative health outcomes and family-based obesity treatment provided to both children and parents is considered to be effective. But the questions is: do children need to come for childhood obesity treatment with parents for it to be effective?

31 May 2017

Radboudumc, iMM Lisboa, PATH team up to test new malaria vaccine concept

The Radboud University Medical Center in the Netherlands, the Instituto de Medicina Molecular Lisboa in Portugal, and PATH in Seattle, Washington announced today that they will collaborate to test a new approach to malaria vaccine development in humans for the first time.

31 May 2017

Small clinical trial reveals promising results of triple immunotherapy in treating rare skin cancer

Three out of four patients treated with an experimental combination of three different therapies for the rare skin cancer known as Merkel cell carcinoma are in complete remission following the treatment, according to study results from a small clinical trial led at Fred Hutchinson Cancer Research Center.

31 May 2017

Investigational compound inhibits cancer-specific mutations in mice

Many malignancies develop as a result of genetic alterations in individual cells. These gene mutations often cause altered proteins that give new, growth-promoting properties to the cell.

30 May 2017

Gene editing technology can introduce hundreds of unintended mutations, study shows

As CRISPR-Cas9 starts to move into clinical trials, a new study published in Nature Methods has found that the gene-editing technology can introduce hundreds of unintended mutations into the genome.

29 May 2017

Dual therapy effective as second-line treatment for patients infected by HIV with multiple mutations

ANRS 12286 MOBIDIP, a clinical trial running in parallel in three countries in sub-Saharan Africa (Cameroon, Burkina Faso, and Senegal), shows that dual therapy with lamivudine and a boosted protease inhibitor is effective as second-line treatment in patients infected by HIV with multiple mutations.

29 May 2017

Dragon Master Foundation to fund DIPG trial that will make patient data available live in the cloud

Dragon Master Foundation has announced plans to provide $300,000 in funding for the first clinical trial that will make patient data available live in the cloud while the trial is underway.

27 May 2017

FDA approves expanded use of Zykadia for first-line treatment of ALK-positive metastatic NSCLC

Novartis today announced the US Food and Drug Administration approved the expanded use of Zykadia (ceritinib) to include the first-line treatment of patients with metastatic non-small cell lung cancer (NSCLC) whose tumors are anaplastic lymphoma kinase (ALK)-positive, as detected by an FDA-approved test.

27 May 2017

Study: Combining non-invasive ventilation and home oxygen therapy can reduce hospital readmissions for chronic COPD patients

Recently published advancements in pulmonary research suggest that the combination of non-invasive ventilation and home oxygen therapy can significantly prolong time to readmission or death for patients with chronic obstructive pulmonary disease following a life-threatening respiratory event or exacerbation.

26 May 2017

ERT’s Centralized LCI Services improve data quality to measure disease progression in respiratory clinical trials

ERT, a global data and technology company that minimizes uncertainty and risk in clinical trials, today introduced an advanced respiratory clinical trial solution to centrally capture, measure and analyze Lung Clearance Index data, in near real-time, to assess lung performance with more precision than traditional spirometry measures.

26 May 2017

Philips sponsors research to help COPD patients breathe easier

Recently published advancements in pulmonary research suggest that the combination of non-invasive ventilation (NIV) and home oxygen therapy (HOT) can significantly prolong time to readmission or death for patients with chronic obstructive pulmonary disease (COPD) following a life-threatening respiratory event or exacerbation. The five-year, multi-center study resulted in prolonged median time to readmission or death by nearly three months, and improved patient health-related quality of life in the first six weeks.

From Philips Healthcare 26 May 2017

Clinical study tests 100-year-old drug in children with autism spectrum disorder

In a small, randomized Phase I/II clinical trial (SAT1), researchers at University of California San Diego School of Medicine say a 100-year-old drug called suramin, originally developed to treat African sleeping sickness, was safely administered to children with autism spectrum disorder (ASD), who subsequently displayed measurable, but transient, improvement in core symptoms of autism.

26 May 2017

Immunotherapy can be more effective in NSCLC patients who received radiation therapy, study shows

A new study by UCLA scientists has found that the breakthrough immunotherapy drug pembrolizumab can be more effective in improving survival in people with non-small cell lung cancer (NSCLC) if they have previously received radiation therapy, compared to those without a history of radiation treatment.

25 May 2017

Researchers present promising approach to create virus- and oncogene-free IPSCs

Induced pluripotent stem cells (IPSCs) hold great promise in regenerative medicine, personalized medicine and drug discovery.

24 May 2017

Innovus Pharma announces launch of AllerVarx for relieving nasal, ocular symptoms in allergic patients

Innovus Pharmaceuticals, Inc., an emerging commercial-stage pharmaceutical company that delivers safe, innovative and effective over-the-counter medicine and consumer care products to improve men's and women's health and respiratory diseases, today announced the launch of AllerVarx in the U.S.

24 May 2017

Clinical Trial News and Research

Common acne medication can slow progress of relapsing-remitting MS, trial shows

Experimental drug increases progression-free survival in pancreatic cancer patients, clinical trial shows

Phase 2 clinical study examines Alzheimer's disease drug to treat adults with Down syndrome

Moffitt researchers hope to improve personalized radiation therapy for head and neck cancer patients

Clinical trial uses small molecule to treat men with incurable prostate cancer

Study finds parent-based obesity treatment without their children could be used to tackle childhood obesity

Radboudumc, iMM Lisboa, PATH team up to test new malaria vaccine concept

Small clinical trial reveals promising results of triple immunotherapy in treating rare skin cancer

Investigational compound inhibits cancer-specific mutations in mice

Gene editing technology can introduce hundreds of unintended mutations, study shows

Dual therapy effective as second-line treatment for patients infected by HIV with multiple mutations

Dragon Master Foundation to fund DIPG trial that will make patient data available live in the cloud

FDA approves expanded use of Zykadia for first-line treatment of ALK-positive metastatic NSCLC

Study: Combining non-invasive ventilation and home oxygen therapy can reduce hospital readmissions for chronic COPD patients

ERT’s Centralized LCI Services improve data quality to measure disease progression in respiratory clinical trials

Philips sponsors research to help COPD patients breathe easier

Clinical study tests 100-year-old drug in children with autism spectrum disorder

Immunotherapy can be more effective in NSCLC patients who received radiation therapy, study shows

Researchers present promising approach to create virus- and oncogene-free IPSCs

Innovus Pharma announces launch of AllerVarx for relieving nasal, ocular symptoms in allergic patients

Event guide: 15th World Clinical Biomarkers & CDx Europe eBook

Latest eBooks

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Driving innovation in Korean drug development

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Applications Engineer