Receptor News and Research

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Promising molecule could stop or slow Parkinson’s

A promising molecule has offered hope for a new treatment that could stop or slow Parkinson’s, something no treatment can currently do.

14 Feb 2020

Universal 'One-Size-Fits-All' Cancer Treatment

Andrew Sewell speaks to News-Medical about his breakthrough research, in which he has discovered a new T-Cell that could treat most cancers.

14 Feb 2020

Understanding stress-induced bladder dysfunction in children

We know that stress can have a profound impact on health. But it's rare to discover a health issue that is caused directly by stress.

13 Feb 2020

Novel drug combination discovered to induce high rates of human beta cell proliferation

Researchers at the Icahn School of Medicine at Mount Sinai have discovered a novel combination of two classes of drugs that, together, cause the highest rate of proliferation ever observed in adult human beta cells- the cells in the pancreas that produce insulin- without harming most other cells in the body.

12 Feb 2020

Discovery identifies an adaptation by cancer cells that promotes metastasis

The discovery identifies an adaptation by cancer cells that facilitates their spreading to distant sites, and the potential for targeting these features to prevent or slow the progression of metastatic hormone receptor-positive breast cancer.

12 Feb 2020

KAIST researchers identify mechanism that fuels a 'domino effect' in cancer drug resistance

KAIST researchers have identified mechanisms that relay prior acquired resistance to the first-line chemotherapy to the second-line targeted therapy, fueling a "domino effect" in cancer drug resistance.

11 Feb 2020

Macrophages migrate from the blood to attack brain tissue shortly after stroke

Macrophages are part of the innate immune system and essential for brain development and function. Using a novel method, scientists from Jena University Hospital, the University of Bonn and the Memorial Sloan Kettering Cancer Center in New York (USA) succeeded in visualizing macrophages that were formed in the bone marrow.

11 Feb 2020

A protein that plays key role in endometrial cancer growth discovered

The hormone estrogen plays many critical roles in men and women, in both healthy tissues and in cancer. In breast and gynecologic cancers, estrogen sends signals to tumors instructing the cancer cells to grow out of control.

11 Feb 2020

Novel melatonin receptor molecules potentially address circadian rhythm disturbances

Like breathing or blinking, behaviors regulated by our circadian rhythms, such as digestion and sleep-wake cycles, go unnoticed by most people.

10 Feb 2020

Researchers culture human blood-brain barrier on a chip

A scrupulous gatekeeper stands between the brain and its circulatory system to let in the good and keep out the bad, but this porter, called the blood-brain barrier, also blocks trial drugs to treat diseases like Alzheimer's or cancer from getting into the brain.

10 Feb 2020

Research reveals novel way to treat cancers using CAR T cell therapy

Too many patients with cancers like multiple myeloma relapse after treatment. This grim reality motivated researchers at Huntsman Cancer Institute at the University of Utah to try to improve the depth and durability of treatment response in multiple myeloma through a new cancer cell targeting mechanism.

10 Feb 2020

CRISPR-edited immune cells can be safely given to cancer patients

The emergence of CRISPR-Cas9 gene-editing technology has spurred hope in both doctors and patients since it shows promise in treating a multitude of diseases, including cancer. For the first time in the United States, a team of scientists has shown that CRISPR-edited immune cells can be safely used to cancer patients.

9 Feb 2020

Study finds link between bladder cancer and collagen receptor

A team of investigators has recently discovered that the collagen receptor DDR1 functionally interacts with the insulin-like growth factor system in regulating bladder cancer.

9 Feb 2020

Georgia State researcher receives $1.67 million federal grant to study gut immunity

Dr. Tim Denning, professor and associate director of the Institute for Biomedical Sciences at Georgia State University, has received a four-year, $1.67 million federal grant to study how an immunological pathway influences inflammatory signaling in the intestine that can lead to chronic human diseases such as inflammatory bowel disease.

9 Feb 2020

Researchers identify involvement of certain cortical areas in the loss of control over food intake

Researchers at UPF, in collaboration with researchers from the University of Mainz (Germany), the Center for Genomic Regulation, Instituto Cajal, Johannes Gutenberg University (Germany), the Autonomous University Barcelona and Hospital del Mar have identified for the first time the involvement of certain cortical areas in the brain in the loss of control over food intake.

9 Feb 2020

New therapeutic strategy for lung cancer and associated secondary tumors

In 20 - 40% of patients with cancer, metastasis (the development of secondary tumors) in the central nervous system (CNS) occurs. CNS metastatis impacts negatively on a patient's quality of life, and is associated with a poor health prognosis.

8 Feb 2020

Researchers reveal new activity above the surface in brain-cell receptors

Like buoys bobbing on the ocean, many receptors float on the surface of a cell's membrane with a part sticking above the water and another underwater, inside the cell's cytoplasm.

7 Feb 2020

CD19 CAR NK cell therapy clinical trial shows encouraging results for hematologic cancers

According to results from a Phase I/IIa trial at The University of Texas MD Anderson Cancer Center, treatment with cord blood-derived chimeric antigen receptor natural killer (NK)-cell therapy targeting CD19 resulted in clinical responses in a majority of patients with relapsed or refractory non-Hodgkin's lymphoma and chronic lymphocytic leukemia, with no major toxicities observed.

6 Feb 2020

Cancer-fighting compound reduces fat in obese mice

Eric Prossnitz, PhD, and his team hope to help 93 million obese Americans fight their fat.

6 Feb 2020

Study suggests potential therapy option for early-stage breast cancer

Radionuclide therapy has proven successful in delaying the growth of disseminated tumor cells (DTCs) in early-stage breast cancer in a small animal model, suggesting its use as a potential adjuvant therapy for retarding the proliferation of DTCs.

5 Feb 2020