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Study: Coronaviruses are adept at imitating human immune proteins involved in COVID-19

Coronaviruses are adept at imitating human immune proteins that have been implicated in severe COVID-19 disease, a study from researchers at Columbia University Vagelos College of Physicians and Surgeons has found.

28 Oct 2020

High dose of radiation eliminates brain tumors in mice without key side effects

Treating cancer without debilitating side effects has long been the holy grail of oncologists, and researchers at the University of California, Irvine, and Switzerland's Lausanne University Hospital may have found it.

28 Oct 2020

Myeloid cells can suppress immune response, promote brain metastasis

Scientists have long believed that the brain protects itself from an aggressive immune response to keep down inflammation. However, that evolutionary control may work against it when a cancer cell attempts to spread to the brain, researchers at the University of Notre Dame have discovered.

27 Oct 2020

DNase coated melanin-like nanospheres for sepsis treatment in severe COVID

As the treatment of severe COVID-19 is very difficult, the researchers from the Korea Research Institute of Biosciences and Biotechnology (KRIBB) suggested that DNase-1 can be utilized to dissolve the neutrophil extracellular traps (NETs), hence halting the further progression of COVID-19.

27 Oct 2020

Study provides novel biomarkers for predicting rheumatoid arthritis patient responsiveness to DMARDs

A new study led by researchers at Queen Mary University of London provides potential novel biomarkers for predicting patient responsiveness to disease modifying anti-rheumatic drugs (DMARDs).

27 Oct 2020

Delaying urgent health issues can be more harmful than the potential risk of COVID-19

More than half a year into the COVID-19 (coronavirus) pandemic, healthcare providers have adapted by offering virtual visits and observing strict safety measures in clinics.

27 Oct 2020

Lung biomarkers may predict severe COVID-19

Two University of New Mexico researchers postulate certain specific biomarkers' relevance in predicting the potential for progression to severe COVID-19 in a paper published on the preprint server bioRxiv*

27 Oct 2020

Early life exposure to air pollution may increase children's body mass index

Exposure to higher air pollution levels and greater population density during the early months of life may be associated with an increase in children's body mass index (BMI).

27 Oct 2020

Cellular senescence variations may control health and onset of age-related diseases

Researchers from Kumamoto University, Japan have proposed that cellular senescence variations during the aging process could lead to control of health and onset of age-related diseases.

27 Oct 2020

Anti-inflammatory mediator may play key role in wound healing

"Wound healing is one of the most complex biological processes," writes Professor Kazumitsu Sugiura and Dr. Kenta Saito from Fujita Health University, Japan, in their article recently published in Nature's Scientific Reports.

27 Oct 2020

Researchers identify a new way to prevent skin reactions in cancer patients

Using the body's immune system to fight cancer has great potential, but can also bring serious side effects, including itchy and painful skin reactions.

27 Oct 2020

Interaction between PTSD and klotho gene may cause premature aging in the brain

Study Finds PTSD Interacts With Klotho Gene, May Cause Premature Aging In The Brain

27 Oct 2020

About 15% of COVID-19-related deaths linked to long-term exposure to air pollution

Long-term exposure to air pollution has been linked to an increased risk of dying from COVID-19 and, for the first time, a study has estimated the proportion of deaths from the coronavirus that could be attributed to the exacerbating effects of air pollution for every country in the world.

27 Oct 2020

Novel insights open up new avenues for treating autoimmune conditions

Immune response is a balancing act: Too much can lead to inflammatory or autoimmune disease; too little could lead to a serious infection. Regulatory T cells, or Tregs, are important players in striking this balance, acting as "brakes" on the immune response so it doesn't go overboard.

27 Oct 2020

Genome-wide screens reveal new helpful and harmful COVID-19 related genes

Researchers at Yale University and the Broad Institute of MIT and Harvard screened hundreds of millions of cells exposed to the COVID-19 and MERS viruses and identified dozens of genes that both enable the viruses to replicate in cells and also those that seem to slam the door on the virus.

27 Oct 2020

Researchers generate a transcriptomic map of the COVID brain

COVID-19 is known to be associated with multiple changes in gene expression, but many of these are also seen in chronic brain conditions as well as in some abnormal mental conditions. A recent study published on the preprint server bioRxiv in October 2020 uncovers the molecular basis of this association.

26 Oct 2020

Research uncovers SARS-CoV-2 viral traits critical for the virus in human airways

A new study published on the preprint server bioRxiv* in October 2020 reports the discovery of important viral genomic features that are crucial to its replication in the human airway cells, and its enhancing mutations which increase the rate of replication and determine its target cells.

26 Oct 2020

Small molecules block SARS-CoV-2 spike-ACE2 attachment

The search includes immunological agents, enzyme inhibitors, and soluble competitive inhibitors. Now, a new study published on the preprint server bioRxiv in October 2020 provides preliminary evidence that small molecules can inhibit viral entry by inhibiting spike-ACE2 attachment.

26 Oct 2020

Neutrophils have more functions in the body than previously thought

Scientists at the Centro Nacional de Investigaciones Cardiovasculares have discovered that neutrophils, the most abundant cells of the innate immune system, have many more functions in the body than previously thought.

23 Oct 2020

Investigational drug offers benefits for patients with chronic kidney disease and type 2 diabetes

The findings, simultaneously published in the New England Journal of Medicine and presented at the American Society of Nephrology's Kidney Week 2020 conference, show the investigational drug finerenone had tangible renal and cardiovascular benefits for patients with chronic kidney disease and type 2 diabetes.

23 Oct 2020