Antibodies News and Research

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Researchers identify new way to prevent pneumococci from entering the brain

An international team of researchers, led from Karolinska Institutet, has identified two receptors on the cells in the blood vessels of the brain that can be blocked and thereby prevent pneumococci from entering the brain.

17 May 2017

Experimental gene therapy proven safe for preserving vision of people with AMD

In a small and preliminary clinical trial, Johns Hopkins researchers and their collaborators have shown that an experimental gene therapy that uses viruses to introduce a therapeutic gene into the eye is safe and that it may be effective in preserving the vision of people with wet age-related macular degeneration.

17 May 2017

Major allergens strongly underrepresented in some immunotherapy against bee stings

Summer is approaching, and for many allergy sufferers this means it is time to start fearing bee stings. "Allergic reactions to insect venoms are potentially life-threatening, and constitute one of the most severe hypersensitivity reactions," explains PD Dr. Simon Blank, research group leader at the Center of Allergy & Environment, a joint undertaking by the Helmholtz Zentrum München and the TUM.

17 May 2017

EPFL scientists develop new antibody-linked biosensor to track drug concentration in the blood

Being able to monitor drug concentration in the blood of a patient is an important aspect of any pharmaceutical treatment. However, this requires equipment and facilities that are often missing from field healthcare in developing countries, but also inhibits the quality of life for patients elsewhere.

16 May 2017

WSU scientists develop new approach to deliver therapeutics to tumors

For the first time, WSU researchers have demonstrated a way to deliver a drug to a tumor by attaching it to a blood cell. The innovation could let doctors target tumors with anticancer drugs that might otherwise damage healthy tissues.

16 May 2017

Study findings could pave way for better drugs to fight against parasitic infections

Immune cells, called macrophages, may rely on a compound to signal an attack to beat back attacks from parasitic worms, according to an international team of researchers, including Zissis C. Chroneos, associate professor of pediatrics, and microbiology and immunology at Penn State College of Medicine.

12 May 2017

Scientists discover free C3d protein that mitigates tumor-induced immunosuppression

In the body, anti-cancer immunity is immobilized by stealth cancer forces. But a natural de-immobilizer has been identified - and it has a vendetta.

12 May 2017

Researchers uncover structural details that make eye-targeting virus a better tool for future therapies

In their quest to replicate themselves, viruses have gotten awfully good at tricking human cells into pumping out viral proteins. That's why scientists have been working to use viruses as forces for good: to deliver useful genes to human cells and help patients who lack important proteins or enzymes.

12 May 2017

Leti's New Deal project could revolutionize IBD therapies for great benefit of patients in the European Union

Leti, a technology research institute of CEA Tech, today announced a European Union project to develop a nanotherapy targeting the molecules involved in inflammatory bowel diseases (IBD), such as Crohn’s disease and ulcerative colitis.

12 May 2017

Scientists reveal how immune cells activate to kill parasitic worms

An international team of researchers including Zissis C. Chroneos, associate professor of pediatrics, and microbiology and immunology at Penn State College of Medicine, reveals how immune cells called macrophages activate to kill parasitic worms.

11 May 2017

Preclinical results of translational research show favorable outcomes in developing Zika virus vaccine

Preclinical results of research by City College of New York scientists and TechnoVax, Inc. in animal models demonstrate favorable outcomes in developing a vaccine against the mosquito-borne Zika virus.

11 May 2017

Study generates comprehensive catalog of diseases linked to variations in HLA genes

A study led by researchers at Vanderbilt University Medical Center and the University of Arizona College of Pharmacy has generated the first comprehensive catalog of diseases associated with variations in human leukocyte antigen genes that regulate the body's immune system.

11 May 2017

UT Southwestern study sheds light on role of hormone ghrelin in blood glucose control

UT Southwestern research investigating the blood glucose-regulatory actions of the hormone ghrelin may have implications for development of new treatments for diabetes.

10 May 2017

Research illuminates how primary colorectal tumors contribute to premetastatic 'niche' formation

Primary colorectal tumors secrete VEGF-A, inducing CXCL1 and CXCR2-positive myeloid-derived suppressor cell (MDSC) recruitment at distant sites and establishing niches for future metastases, report Medical University of South Carolina investigators in an article published online ahead of print on April 28, 2017 by Cancer Research.

10 May 2017

Novel nanoscale molecular slingshot could ‘shoot’ and deliver drugs at precise disease locations

An international team of researchers from the University of Rome Tor Vergata and the University of Montreal has reported, in a paper published this week in Nature Communications, the design and synthesis of a nanoscale molecular slingshot made of DNA that is 20,000 times smaller than a human hair.

9 May 2017

New UCI Malaria Initiative aims to disrupt deadly disease transmission in Africa

University of California, Irvine vector biologist Anthony James will lead a multimillion-dollar effort to cultivate new strains of mosquitoes to fight malaria in Africa.

9 May 2017

Study reveals critical role of omega-3 fatty acids in preserving integrity of the blood-brain barrier

Already extolled for their health benefits as a food compound, omega-3 fatty acids now appear to also play a critical role in preserving the integrity of the blood-brain barrier, which protects the central nervous system from blood-borne bacteria, toxins and other pathogens, according to new research from Harvard Medical School.

5 May 2017

Easing cellular traffic jams in Huntington’s disease may save brain cells

Working with mouse, fly and human cells and tissue, Johns Hopkins researchers report new evidence that disruptions in the movement of cellular materials in and out of a cell's control center - the nucleus- appear to be a direct cause of brain cell death in Huntington's disease, an inherited adult neurodegenerative disorder.

5 May 2017

Mayo Clinic scientists develop novel nanoparticle to shrink tumors, prevent breast cancer recurrence

A Mayo Clinic research team has developed a new type of cancer-fighting nanoparticle aimed at shrinking breast cancer tumors, while also preventing recurrence of the disease.

2 May 2017

Researchers find persistence of Zika virus in cerebrospinal fluid, lymph nodes of rhesus monkeys

Zika virus can persist in cerebrospinal fluid (CSF), lymph nodes and colorectal tissue of infected rhesus monkeys for weeks after the virus has been cleared from blood, urine and mucosal secretions, according to a study published online in Cell.

28 Apr 2017

Antibodies News and Research

Researchers identify new way to prevent pneumococci from entering the brain

Experimental gene therapy proven safe for preserving vision of people with AMD

Major allergens strongly underrepresented in some immunotherapy against bee stings

EPFL scientists develop new antibody-linked biosensor to track drug concentration in the blood

WSU scientists develop new approach to deliver therapeutics to tumors

Study findings could pave way for better drugs to fight against parasitic infections

Scientists discover free C3d protein that mitigates tumor-induced immunosuppression

Researchers uncover structural details that make eye-targeting virus a better tool for future therapies

Leti's New Deal project could revolutionize IBD therapies for great benefit of patients in the European Union

Scientists reveal how immune cells activate to kill parasitic worms

Preclinical results of translational research show favorable outcomes in developing Zika virus vaccine

Study generates comprehensive catalog of diseases linked to variations in HLA genes

UT Southwestern study sheds light on role of hormone ghrelin in blood glucose control

Research illuminates how primary colorectal tumors contribute to premetastatic 'niche' formation

Novel nanoscale molecular slingshot could ‘shoot’ and deliver drugs at precise disease locations

New UCI Malaria Initiative aims to disrupt deadly disease transmission in Africa

Study reveals critical role of omega-3 fatty acids in preserving integrity of the blood-brain barrier

Easing cellular traffic jams in Huntington’s disease may save brain cells

Mayo Clinic scientists develop novel nanoparticle to shrink tumors, prevent breast cancer recurrence

Researchers find persistence of Zika virus in cerebrospinal fluid, lymph nodes of rhesus monkeys

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