Bone Marrow News and Research

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Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

Researchers reveal unique signature of genes expressed by hematopoietic stem cells

Hematopoietic stem cells (HSCs) have the capacity to both self-renew and differentiate into all mature blood cell types, making them promising treatments for a variety of diseases.

2 Mar 2022

Study explores dictionary learning-based bridge integration method for data harmonization of single-cell analysis

In a new study, researchers developed and elucidated a ‘bridge integration’ method to harmonize single-cell ribonucleic acid sequencing datasets.

1 Mar 2022

Study reveals how the immune system can be triggered to attack cancer cells

New research from the University of East Anglia and Quadram Institute reveals how our immune system can be triggered to attack cancer cells.

1 Mar 2022

Researchers demonstrate the powerful gene silencing effects of HDO technology

T and B lymphocytes, which are part of a group of immune cells commonly called white blood cells, work together to eliminate foreign invaders in the body such as viruses.

28 Feb 2022

Study reveals how the immune system can be triggered to fight cancer cells

New research from the University of East Anglia and Quadram Institute reveals how our immune system can be triggered to attack cancer cells.

25 Feb 2022

Tissue engineering advance could one day help patients regrow bones

Researchers have used sound waves to turn stem cells into bone cells, in a tissue engineering advance that could one day help patients regrow bone lost to cancer or degenerative disease.

23 Feb 2022

Study shows BCG vaccine provides no protection against SARS-CoV-2 in mice and hamsters

Researchers investigated the effectiveness of the BCG vaccines against SARS-CoV-2 infections using three animal models.

23 Feb 2022

Researchers discover how pre-transplant chemotherapy facilitates the replacement of microglial cells

More than 50,000 bone marrow-derived stem cell transplants are performed worldwide each year to treat a wide range of conditions, including brain diseases.

21 Feb 2022

Partially matched blood cells could help cure people with both cancer and HIV

Following the news that a third person has been cured of HIV, a Northwestern Medicine expert says partially matched blood cells could be used to cure many people living with both cancer and HIV.

21 Feb 2022

Study shows link between oral microbiome and naturally occurring alveolar bone loss

It is becoming increasingly clear that the human microbiome – the collection of bacteria, viruses and fungi that live on and within us – significantly contributes to our health.

17 Feb 2022

Optical genome mapping holds potential to become an important component of leukemia diagnostics

Optical genome mapping involves the extraction of very long DNA molecules, for example routinely collected blood samples or bone marrow material from patients.

17 Feb 2022

Combating leukemia cells by disrupting their energy maintenance mechanism

Acute myeloid leukemia, which affects blood and bone marrow cells, is a particularly dangerous form of cancer. More than half of patients under the age of 60 die.

17 Feb 2022

Study investigates what causes blood malignancies linked to gene therapy for sickle cell disease

Gene therapy trials for sickle cell disease have been showing great promise, even offering hope of a cure. But in early 2021, the trials ground to a halt after reports of blood malignancies in two people in a trial sponsored by bluebird bio.

16 Feb 2022

Antibodies become more powerful for at least six months after COVID-19 vaccination

For at least six months after COVID-19 vaccination, antibodies produced by immune cells become steadily more formidable and more precisely targeted against the virus that causes COVID-19, according to a study of the antibody response to the Pfizer-BioNTech vaccine by researchers at Washington University School of Medicine in St. Louis.

16 Feb 2022

Stem cell infusion improves the survival of mice with sepsis

A one-time infusion of stem cells from bone marrow improves the survival of mice with sepsis, shows a study published today in eLife.

15 Feb 2022

Study suggests that epigenetic memory in innate immune cells could be the key to explaining long COVID

A new study may provide a partial explanation for the long-term immunologic phenomena associated with COVID-19.

15 Feb 2022

Hollings researcher receives grant to fight complications after pediatric bone marrow transplant

MUSC Hollings Cancer Center researcher Sophie Paczesny, M.D., Ph.D., recently received a four-year grant from the National Heart, Lung, and Blood Institute to investigate solutions to help doctors to fight complications after pediatric bone marrow transplantation (BMT).

12 Feb 2022

Using sugar molecules for in vivo tracking of unlabeled stem cells

A Johns Hopkins Medicine scientist who spent 30 years figuring out how to put chemical labels into cells to track their movement in living tissues has found that certain self-renewing stem cells have built-in tracers - made out of sugars - that can do the job without added chemical "labels" when injected into mouse brains.

8 Feb 2022

Research reveals a possible strategy to prevent B-cell acute lymphoblastic leukemia

Short-term treatment with the drug ruxolitinib prevents B-cell acute lymphoblastic leukemia (B-ALL) in mice that have a genetic predisposition to the disease.

8 Feb 2022

New personalized test to detect leukemia relapse sooner and avoid false negative results

Researchers have developed a new protocol for monitoring acute lymphoblastic leukemia (ALL), the most common cancer in children, to inform more effective treatment strategies and detect disease recurrence.

7 Feb 2022

Bone Marrow News and Research

Further Reading

Researchers reveal unique signature of genes expressed by hematopoietic stem cells

Study explores dictionary learning-based bridge integration method for data harmonization of single-cell analysis

Study reveals how the immune system can be triggered to attack cancer cells

Researchers demonstrate the powerful gene silencing effects of HDO technology

Study reveals how the immune system can be triggered to fight cancer cells

Tissue engineering advance could one day help patients regrow bones

Study shows BCG vaccine provides no protection against SARS-CoV-2 in mice and hamsters

Researchers discover how pre-transplant chemotherapy facilitates the replacement of microglial cells

Partially matched blood cells could help cure people with both cancer and HIV

Study shows link between oral microbiome and naturally occurring alveolar bone loss

Optical genome mapping holds potential to become an important component of leukemia diagnostics

Combating leukemia cells by disrupting their energy maintenance mechanism

Study investigates what causes blood malignancies linked to gene therapy for sickle cell disease

Antibodies become more powerful for at least six months after COVID-19 vaccination

Stem cell infusion improves the survival of mice with sepsis

Study suggests that epigenetic memory in innate immune cells could be the key to explaining long COVID

Hollings researcher receives grant to fight complications after pediatric bone marrow transplant

Using sugar molecules for in vivo tracking of unlabeled stem cells

Research reveals a possible strategy to prevent B-cell acute lymphoblastic leukemia

New personalized test to detect leukemia relapse sooner and avoid false negative results

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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