Medicinal Chemistry News and Research

RSS

New method of developing antibiotics

University of Minnesota and University of Michigan researchers have discovered a new method of developing antibiotics, an important step in fighting the growing number of drug-resistant infections.

12 Sep 2006

Genetics is a very strong component of obesity

Nearly 6 percent of morbidly obese children and adults have a genetic defect that keeps them feeling like their stomach is running on empty, no matter how much they have eaten.

6 Aug 2006

Darunavir - first molecule to treat drug-resistant HIV

Doctors have their first FDA-approved tool to treat drug-resistant HIV thanks to a new molecule created by a Purdue University researcher.

2 Aug 2006

Birch bark compound may be potent prostate cancer fighter

A compound found in the bark of the white birch tree - betulonic acid, a derivative of betulinol - may finally have been rendered a water-soluble, bio-available drug, and is already showing the potential to be a possible agent against prostate cancer - in cell culture and in an animal model.

25 Jul 2006

Dopamine drug leads to new neurons and recovery of function in Parkinson's

In preliminary results, researchers have shown that a drug which mimics the effects of the nerve-signaling chemical dopamine causes new neurons to develop in the part of the brain where cells are lost in Parkinson's disease (PD).

5 Jul 2006

Dopamine drug may lead to new ways of treating Parkinson's and other neurodegenerative diseases

Researchers have shown that a drug which mimics the effects of the nerve-signaling chemical dopamine causes new neurons to develop in the part of the brain where cells are lost in Parkinson's disease

4 Jul 2006

Level of selenium-containing proteins in the body instrumental in preventing cancer

Selenium, an essential dietary mineral that can act as an antioxidant when incorporated into proteins, has been shown in many studies to reduce the incidence of cancers -- notably lung, colorectal and prostate.

23 May 2006

Nimesulide fights breast cancer by targeting key enzyme

A pain-killing medication appears to halt the production of an enzyme that is key to a common form of breast cancer, a new study using tissue cultures suggests.

16 Apr 2006

New therapy proven to be effective in the treatment of MRS

Cosmetic considerations and a perceived lack of patent opportunities could be stopping the pharmaceutical and healthcare industries from investing in the development of a new therapy proven to be effective in the treatment of MRSA.

6 Apr 2006

Scientists discover structure of malaria defense process

Scientists from two universities in Italy and Virginia Tech in the United States have determined the structure of a protein that is responsible for the production xanthurenic acid (XA) in Anopheles gambiae, the malaria carrying mosquitoes.

4 Apr 2006

University of Michigan researchers target stubborn gram-negative bacteria

Ronald Woodard's team set out looking for a way to kill a stubborn type of bacteria and they succeeded - but not in the way he expected.

9 Mar 2006

ATF2 protein may play a crucial role in cancer's ability to resist chemotherapy and radiation treatment

Researchers at Purdue University have discovered a molecular mechanism that may play a crucial role in cancer's ability to resist chemotherapy and radiation treatment and that also may be involved in Alzheimer's and heart disease.

9 Mar 2006

Grapefruit reduces risk from heart disease

Heart disease patients who eat one grapefruit daily can significantly reduce the levels of cholesterol in their blood in comparison to patients who do not eat the fruit, a new study has found. Chronic high blood cholesterol is a major risk factor for heart disease.

16 Feb 2006

Alternative method to produce heparin

Researchers at Rensselaer Polytechnic Institute and University of North Carolina at Chapel Hill have discovered an alternative way to produce heparin, a drug commonly used to stop or prevent blood from clotting.

7 Feb 2006

Galapagos and Cancer Research Technology announce new anti-cancer drug discovery collaboration

Galapagos NV and Cancer Research Technology ("CRT"), specialists in oncology drug discovery and commercialization, a wholly owned company of Cancer Research UK, announced today that they have entered into a new collaboration in anti-cancer drug discovery research.

19 Jan 2006