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Inhalable ‘aerogel’ induces immune response against COVID-19 in the lungs of mice

An inhalable 'aerogel' loaded with DNA that encodes for the SARS-CoV-2 spike protein successfully induces an immune response against COVID-19 in the lungs of mice, according to new research conducted at Penn State.

16 Mar 2022

Potential Covid-19 vaccine may offer an inexpensive, easy-to-store alternative to RNA vaccines

While many people in wealthier countries have been vaccinated against Covid-19, there is still a need for vaccination in much of the world.

16 Mar 2022

Ethyl lauroyl arginine hydrochloride (ELAH) nasal spray as potent antiviral against SARS-CoV-2

Researchers evaluate the virucidal effects of ELAH against SARS-CoV-2 and human coronavirus-229E in a nasal spray formulation.

15 Mar 2022

Acacetin shows potency against SARS-CoV-2 spike protein

Researchers use molecular docking to screen phytocompounds and evaluate their binding affinity with SARS-CoV-2.

15 Mar 2022

Anti-spike IgG dynamics after 2nd BNT162b2 COVID-19 vaccine dose in Japanese health care workers

Researchers investigate the dynamics of anti-spike IgG levels against the SARS-CoV-2 spike protein in Japanese healthcare workers.

15 Mar 2022

Researchers receive grant to find answers to taste loss in COVID patients

Up to 80% of individuals who've had COVID-19 report temporary or lasting changes in their sense of taste, and scientists are working to better understand the biological basis of why, including whether our taste buds are a direct virus target.

15 Mar 2022

Omicron emergence in South Africa associated with increased reinfection risk, analysis finds

The Omicron variant of SARS-CoV-2 evades immunity from prior infection, an analysis of routine surveillance data from South Africa indicates.

15 Mar 2022

Do anti-nucleocapsid antibodies affect COVID-19 immune reactions?

Researchers have been investigating the potential for vaccines and treatments against the nucleocapsid protein of SARS-CoV-2.

15 Mar 2022

Study finds elevated inflammation in macrophages months after mild COVID-19

There is a lack of understanding as to why some people suffer from long-lasting symptoms after COVID-19 infection.

15 Mar 2022

Using mRNA to introduce gene editor into human muscle stem cells

Mutations that lead to muscle atrophy can be repaired with the gene editor CRISPR-Cas9. A team led by ECRC researcher Helena Escobar has now introduced the tool into human muscle stem cells for the first time using mRNA, thus discovering a method suitable for therapeutic applications.

14 Mar 2022

New Phase 1 clinical trial of mRNA HIV vaccine enrolls first participant

The first 12 study participants have been enrolled in a new Phase 1 clinical trial using the messenger ribonucleic acid (mRNA) vaccine technology developed by Moderna.

14 Mar 2022

NIH launches Phase 1 clinical trial evaluating three experimental mRNA HIV vaccines

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has launched a Phase 1 clinical trial evaluating three experimental HIV vaccines based on a messenger RNA (mRNA) platform—a technology used in several approved COVID-19 vaccines.

14 Mar 2022

Protection against SARS-CoV-2 Omicron variant by hetero-bivalent nanobodies

A new study investigated the broad-spectrum protection provided by hetero-bivalent nanobodies against SARS-CoV-2 variants of concern, such as Omicron.

14 Mar 2022

Study shows the mutations leading to omicron variant did not help virus escape recognition by T cells

People who gained immunity - either through vaccination or exposure - against the original strain of SARS-CoV-2, the virus that causes COVID-19, also are likely to have some protection against the pathogen's omicron variant.

11 Mar 2022

In silico screening and testing of FDA approved drugs inhibiting SARS-CoV-2 spike protein cleavage

Researchers screened 5,000 Food and Drug Association-approved drugs to identify repurposed drugs targeting SARS-CoV-2 spike protein cleavage at both S1/S2 boundary and S2’.

11 Mar 2022

Study suggests increased durability of immune responses towards SARS-CoV-2 spike protein after BNT62b2 booster

Researchers evaluated the immune responses after boosting with Pfizer's BNT162b2 vaccine.

11 Mar 2022

Cross-species infectivity of SARS-CoV-2 variants correlated with prevalence

New research discusses the role of mutations in the receptor-binding domain of the spike protein in the generation of antibody resistance and loss of vaccine efficacy.

10 Mar 2022

Quantification of hydrophobic interactions encoded by FP1 sequences of SARS-CoV-2 and MERS-CoV by single-molecule force measurements

Researchers quantified hydrophobic interactions encoded by fusion peptide 1 sequences of SARS-CoV-2 and MERS-CoV using single-molecule force measurements.

10 Mar 2022

The trajectory of B-cell immunity six months after mRNA vaccination

Researchers assess SARS-CoV-2 antibodies in individuals vaccinated with a mRNA COVID-19 vaccine six months after receiving their second dose.

10 Mar 2022

How will mutations change the SARS-CoV-2 spike protein in the future?

A new Cells review discusses the factors that affect the function of the SARS-CoV-2 S protein and provides theoretical limits of this viral protein.

8 Mar 2022

Spike Protein News and Research

Inhalable ‘aerogel’ induces immune response against COVID-19 in the lungs of mice

Potential Covid-19 vaccine may offer an inexpensive, easy-to-store alternative to RNA vaccines

Ethyl lauroyl arginine hydrochloride (ELAH) nasal spray as potent antiviral against SARS-CoV-2

Acacetin shows potency against SARS-CoV-2 spike protein

Anti-spike IgG dynamics after 2nd BNT162b2 COVID-19 vaccine dose in Japanese health care workers

Researchers receive grant to find answers to taste loss in COVID patients

Omicron emergence in South Africa associated with increased reinfection risk, analysis finds

Do anti-nucleocapsid antibodies affect COVID-19 immune reactions?

Study finds elevated inflammation in macrophages months after mild COVID-19

Using mRNA to introduce gene editor into human muscle stem cells

New Phase 1 clinical trial of mRNA HIV vaccine enrolls first participant

NIH launches Phase 1 clinical trial evaluating three experimental mRNA HIV vaccines

Protection against SARS-CoV-2 Omicron variant by hetero-bivalent nanobodies

Study shows the mutations leading to omicron variant did not help virus escape recognition by T cells

In silico screening and testing of FDA approved drugs inhibiting SARS-CoV-2 spike protein cleavage

Study suggests increased durability of immune responses towards SARS-CoV-2 spike protein after BNT62b2 booster

Cross-species infectivity of SARS-CoV-2 variants correlated with prevalence

Quantification of hydrophobic interactions encoded by FP1 sequences of SARS-CoV-2 and MERS-CoV by single-molecule force measurements

The trajectory of B-cell immunity six months after mRNA vaccination

How will mutations change the SARS-CoV-2 spike protein in the future?

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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