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Nanocarrier stimuli-activated gene delivery

One approach to developing tumor-specific drug delivery agents is to create nanomaterials that release a therapeutic payload only after reaching their intended target.

29 Jan 2007

Design of gold nanoparticles for magnetic resonance imaging

Molecular complexes containing the element gadolinium are proven agents for increasing the diagnostic utility of magnetic resonance imaging (MRI), but their use in detecting small tumors is limited by the relatively weak signal these agents produce.

29 Jan 2007

Polymer nanoparticles for immunotherapy from encapsulated tumor-associated antigens and whole tumor cells

Using a biodegradable nanoparticle as a means of delivering tumor cell debris and proteins to the immune system, investigators at Yale University have developed a promising new method for creating therapeutic anticancer vaccines.

29 Jan 2007

Nanoscale "egg" to deliver platinum to tumor cells

Researchers at the Hong Kong University of Science and Technology have developed a nanoscale "egg" that could safely deliver platinum, a known anticancer agent, to tumor cells.

22 Jan 2007

Improved effectiveness of partner notification for patients with sexually transmitted infections

Doctors should encourage patients with sexually transmitted infections to tell their partners to seek treatment and, in some cases, provide home testing kits or drugs to help reduce infection rates, says a new study on British Medical Journal website.

18 Jan 2007

Gambling addiction and its treatment within the NHS

In its hard-hitting report, Gambling addiction and its treatment within the NHS, the BMA is calling for gambling to be a recognised addiction that requires treatment on the NHS.

16 Jan 2007

Microfluidics gives boost to protein crystallization

Proteins produced by cancer cells are among the common targets for anticancer agents, and thanks to efforts in proteomics and cancer genomics, the number of potential protein targets is increasing exponentially.

16 Jan 2007

Nanoparticles yield delivery tools for therapeutic nucleic acids

Cancer researchers hold great hope that nucleic acid-based therapeutics, such as anticancer genes, antisense oligonucleotides, and small interfering RNA (siRNA) molecules, will prove to be powerful antitumor agents.

16 Jan 2007

Biomimetic amplification of nanoparticle homing to tumors

A collaborative, multidisciplinary team of researchers has created nanoparticles that act much like a developing clot to target tumors.

16 Jan 2007

Optical and magnetic resonance imaging of cell death and platelet activation using annexin A5-functionalized quantum dots

By combining a quantum dot with a novel carrier of the magnetic resonance imaging (MRI) agent gadolinium, a team of investigators at the University of Maastricht, in The Netherlands, has developed a nanoparticle that can spot apoptosis, or programmed cell death, using both MRI and fluorescence imaging.

8 Jan 2007

In vivo biodistribution and highly efficient tumour targeting of carbon nanotubes in mice

In the first experiment of its kind, investigators at the Center for Cancer Nanotechnology Excellence Focused on Therapy Response (CCNE-TR), based at Stanford University, have shown that single-walled carbon nanotubes (SWCNTs) wrapped in poly(ethylene glycol), or PEG, can successfully target tumors in living animals.

8 Jan 2007

Rapid and label-free nanomechanical detection of biomarker transcripts in human RNA

Researchers from the Swiss Nanoscience Institute in Basel have developed a rapid method to detect the activity of a gene involved in controlling tumor growth.

18 Dec 2006

Characterizing the environmental, health, and safety implications of nanotechnology

A new analysis of the Federal government’s efforts to study the environmental, health, and safety (EHS) implications of nanotechnology concludes that sound management will play as important a role as good science when it comes to addressing these concerns.

18 Dec 2006

Better magnetic nanoparticles

Using a polymer coating designed to resemble the outer surface of a cell membrane, a team of investigators led by Steve Armes, Ph.D., of the University of Sheffield in the United Kingdom, has created a highly stable, biocompatible magnetic nanoparticle expected to improve the sensitivity of magnetic resonance imaging (MRI).

18 Dec 2006

New X-ray microscope shows nanomaterials in 3D

Using a new x-ray microscope that can look at nanomaterials in three dimensions, an international research team has produced the first detailed atomic structure of a core-shell nanoparticle.

18 Dec 2006

Dual-mode nanoparticle probes for high-performance magnetic resonance and fluorescence imaging of neuroblastoma

Nanoscale, inorganic fluorescent imaging agents such as quantum dots have become an important tool for researchers studying key biomolecules involved in cancer.

18 Dec 2006

Biofunctional organic nanocrystals for quantitative detection of pathogen deoxyribonucleic acid

Waiting a day or more to get lab results back from the doctor's office soon could become a thing of a past.

4 Dec 2006

High throughput quantification of protein expression of cancer antigens in tissue microarray using quantum dot nanocrystals

In attempt to identify biological markers, or biomarkers, that can signal the presence of cancer and help oncologists determine the best course of therapy when cancer is present, teams of investigators are scouring stored tissue samples obtained from thousands of cancer patients.

4 Dec 2006

Nonlithographic fabrication of microfluidic devices

Typically, researchers create microfluidic devices using the same lithographic techniques and tools used to fabricate computer chips. Lithography is expensive and slow, factors that could limit the ultimate utility of microfluidic devices in clinical applications.

4 Dec 2006

Bird flu hits another farm in South Korea

A second outbreak of the virulent H5N1 strain of bird flu at another poultry farm has been confirmed by South Korean authorities; the farm is just 3 km from the first case in North Cholla province in the country's southwest.

29 Nov 2006

Website News and Research

Nanocarrier stimuli-activated gene delivery

Design of gold nanoparticles for magnetic resonance imaging

Polymer nanoparticles for immunotherapy from encapsulated tumor-associated antigens and whole tumor cells

Nanoscale "egg" to deliver platinum to tumor cells

Improved effectiveness of partner notification for patients with sexually transmitted infections

Gambling addiction and its treatment within the NHS

Microfluidics gives boost to protein crystallization

Nanoparticles yield delivery tools for therapeutic nucleic acids

Biomimetic amplification of nanoparticle homing to tumors

Optical and magnetic resonance imaging of cell death and platelet activation using annexin A5-functionalized quantum dots

In vivo biodistribution and highly efficient tumour targeting of carbon nanotubes in mice

Rapid and label-free nanomechanical detection of biomarker transcripts in human RNA

Characterizing the environmental, health, and safety implications of nanotechnology

Better magnetic nanoparticles

New X-ray microscope shows nanomaterials in 3D

Dual-mode nanoparticle probes for high-performance magnetic resonance and fluorescence imaging of neuroblastoma

Biofunctional organic nanocrystals for quantitative detection of pathogen deoxyribonucleic acid

High throughput quantification of protein expression of cancer antigens in tissue microarray using quantum dot nanocrystals

Nonlithographic fabrication of microfluidic devices

Bird flu hits another farm in South Korea

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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