Clinical Trial News and Research

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University of Miami to begin clinical trial for testing DNA-based Zika vaccine

The University of Miami Miller School of Medicine will soon begin one of the nation's first full-scale Zika vaccine clinical trials testing the National Institutes of Health's (NIH) experimental DNA-based vaccine.

31 Mar 2017

Combination of TTFields with standard therapies may improve survival in pancreatic cancer patients

Novocure announced today results from the second cohort of its phase 2 pilot PANOVA trial studying Tumor Treating Fields (TTFields) in combination with nab-paclitaxel and gemcitabine for the treatment of advanced pancreatic cancer.

31 Mar 2017

New research to explore how socio-economic factors, other health concerns affect cancer treatment

How do health and socio-economic factors impact the nearly 1.7 million people diagnosed with cancer each year? RTI International plans to explore this through a new Robert Wood Johnson Foundation grant.

31 Mar 2017

Phase 2 clinical study of investigational Zika vaccine begins in the U.S., Central and South America

Vaccinations have begun in a multi-site Phase 2/2b clinical trial testing an experimental DNA vaccine designed to protect against disease caused by Zika infection.

31 Mar 2017

PAREXEL introduces patient sensor solution for improved data collection in clinical trials

PAREXEL International Corporation, a leading global biopharmaceutical services provider, today announced the launch of its patient sensor solution, a new offering that securely captures, transmits, stores, and visualises study subject data in clinical trials.

From Parexel 31 Mar 2017

GHIT Fund invests in phase 3 clinical trial for pediatric formulation of ‘snail fever’ drug

The Global Health Innovative Technology Fund, a unique Japanese public-private partnership formed to battle infectious diseases around the globe, today announced 11 new investments totaling US$23 million that could help deliver a range of new innovative therapies for a host of debilitating conditions.

31 Mar 2017

Clinical research trial investigates new treatment approach for early-stage eye melanoma

A first-of-its-kind, potentially groundbreaking new option for treating a form of eye cancer is now in its first phase-1 clinical research trial at Wills Eye Hospital in Philadelphia.

30 Mar 2017

Researchers enhance safety, effectiveness of potential HIV vaccine using on/off genetic switch

By engineering an on/off switch into a weakened form of HIV, University of Nebraska-Lincoln researchers have enhanced the safety and effectiveness of a potential vaccine for the virus that has killed approximately 35 million people during the past 35 years.

30 Mar 2017

Rare ‘beneficial’ genetic mutations may provide clues to preventing heart attacks

Natural genetic changes can put some people at high risk of certain conditions, such as breast cancer, Alzheimer's disease or high blood pressure. But in rare cases, genetic errors also can have the opposite effect, protecting individuals with these helpful genetic mistakes from developing common diseases.

30 Mar 2017

Higher nut intake may help reduce risk of CVD, total cancer and all-cause mortality

In a systematic review and dose-response meta-analysis of prospective studies published in BMC Medicine, researchers looked at the association of nut consumption and risk of cardiovascular disease (CVD), total cancer, and all-cause and cause-specific mortality in adults.

29 Mar 2017

Study explores new immunotherapy combinations to treat prostate cancer

Prostate cancer, notoriously resistant to immunotherapy due to its immunologically cool nature, triggers two pathways to chill an immune attack after one immunotherapy drug fires up the immune system, researchers at The University of Texas MD Anderson Cancer Center report in Nature Medicine.

29 Mar 2017

Man with quadriplegia uses implanted technologies to restore arm and hand movements

Bill Kochevar grabbed a mug of water, drew it to his lips and drank through the straw. His motions were slow and deliberate, but then Kochevar hadn't moved his right arm or hand for eight years.

29 Mar 2017

Higher vitamin D levels linked to lower cancer risk, study suggests

Increasing vitamin D levels may lower risk for developing cancer, according to a study conducted by Creighton University with cooperation from the University of California San Diego.

28 Mar 2017

Public-private collaboration to develop more accurate methods of tracking cancer progression

Columbia University Medical Center and NewYork-Presbyterian, in coordination with the Foundation for the National Institutes of Health Biomarkers Consortium, is launching a three-year research collaboration to develop new methods for analyzing digital images that track a patient's response to cancer therapy.

28 Mar 2017

Researchers develop new graphene-based neural probes for recording brain activity in high resolution

Measuring brain activity with precision is essential to developing further understanding of diseases such as epilepsy and disorders that affect brain function and motor control.

27 Mar 2017

Probing the brain in high resolution with graphene based neural probes

Graphene-based transistors enable a flexible neural probe with excellent signal-to-noise ratio. Such probes are useful for examining neural activity for understanding diseases, as well as in neuroprosthetics for control of artificial limbs.

27 Mar 2017

First national survey reveals high burden of iodine deficiency among Israelis

62% of school-age children and 85% of pregnant women in Israel have low iodine intakes, according to the country's first national iodine survey. Government funding and legislation, and a government-regulated program of salt or food iodization, are essential to reducing the deficiency, which poses a high risk of impaired neurological development.

27 Mar 2017

SNIFF study to examine safety, efficacy of nasal insulin for treating Alzheimer’s disease

Can insulin, the hormone used for nearly a century to treat diabetes, improve cognition, memory and daily function in people with mild cognitive impairment or mild dementia due to Alzheimer's disease? Rush University Medical Center is testing this innovative potential treatment as part of a new nationwide study.

25 Mar 2017

Immunotherapy drug becomes first FDA-approved treatment for metastatic MCC

The U.S. Food and Drug Administration yesterday granted accelerated approval to the checkpoint inhibitor Bavencio (avelumab) for the treatment of patients with metastatic Merkel cell carcinoma (MCC), including those who have not received prior chemotherapy.

25 Mar 2017

New CDISC data standard assists in development of potential Ebola treatments

The Clinical Data Interchange Standards Consortium and the Infectious Diseases Data Observatory announce the availability of a new standard to assist in the collection, aggregation and analysis of Ebola virus disease research data.

24 Mar 2017

Clinical Trial News and Research

University of Miami to begin clinical trial for testing DNA-based Zika vaccine

Combination of TTFields with standard therapies may improve survival in pancreatic cancer patients

New research to explore how socio-economic factors, other health concerns affect cancer treatment

Phase 2 clinical study of investigational Zika vaccine begins in the U.S., Central and South America

PAREXEL introduces patient sensor solution for improved data collection in clinical trials

GHIT Fund invests in phase 3 clinical trial for pediatric formulation of ‘snail fever’ drug

Clinical research trial investigates new treatment approach for early-stage eye melanoma

Researchers enhance safety, effectiveness of potential HIV vaccine using on/off genetic switch

Rare ‘beneficial’ genetic mutations may provide clues to preventing heart attacks

Higher nut intake may help reduce risk of CVD, total cancer and all-cause mortality

Study explores new immunotherapy combinations to treat prostate cancer

Man with quadriplegia uses implanted technologies to restore arm and hand movements

Higher vitamin D levels linked to lower cancer risk, study suggests

Public-private collaboration to develop more accurate methods of tracking cancer progression

Researchers develop new graphene-based neural probes for recording brain activity in high resolution

Probing the brain in high resolution with graphene based neural probes

First national survey reveals high burden of iodine deficiency among Israelis

SNIFF study to examine safety, efficacy of nasal insulin for treating Alzheimer’s disease

Immunotherapy drug becomes first FDA-approved treatment for metastatic MCC

New CDISC data standard assists in development of potential Ebola treatments

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