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New York City’s initial lockdown reduced coronavirus spread by 70 percent, study says

A team of researchers at Columbia University and the New York City Department of Health and Mental Hygiene have shown that this move by the government was effective in reducing the spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes the coronavirus disease (COVID-19).

16 Sep 2020

Candidate monoclonal antibody shows hope as COVID-19 treatment

Researchers in the United States have described the effectiveness of a candidate monoclonal antibody currently being evaluated in a Phase 1 trial as a therapy for coronavirus disease 2019 (COVID-19) and its causative agent, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

16 Sep 2020

NTU-incubated start-up plans clinical trial of new slow-release pill for Parkinson’s disease

Materials scientists from Nanyang Technological University, Singapore (NTU Singapore) have developed a new pill which uses the stomach as a drug reservoir and delivers medicines slowly over time to patients with Parkinson's disease (PD).

16 Sep 2020

Curi Bio Announces Mantarray™ Platform for Analysis of 3D Engineered Muscle Tissues for Discovery of New Therapeutics

Curi Bio today announced the Mantarray™ platform for human-relevant 3D engineered muscle tissue (EMT) analysis.

From Curi Bio 16 Sep 2020

Pfizer's anti-viral 3CL protease inhibitor shows antiviral potential against SARS-CoV-2

Now, a new study by researchers from Pfizer, University of Arizona, Purdue University, The Scripps Research Institute, and UC San Diego School of Medicine and published on the preprint server bioRxiv in September 2020 reports that an enzyme inhibitor may act in synergism with the approved antiviral remdesivir to suppress viral replication in COVID-19.

16 Sep 2020

Can amodiaquine short circuit this pandemic?

A recent study by the US researchers highlights the value of the human organ chip technology as a more robust and physiologically relevant platform for rapid drug repurposing, and suggest that amodiaquine may be used to prevent the infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

15 Sep 2020

3D cluster of cells could enhance myocardial repair

Cell therapy for cardiac regeneration, while promising, has been hampered by issues with long-term survival of the transplanted cells.

15 Sep 2020

New antibody assay for COVID-19 promises sensitive mass-scale detection

A new paper by researchers at McMaster University and Hamilton Health Sciences, published on the preprint server medRxiv in September 2020, reports on the development of a serologic assay that is suitable for sensitive high-throughput antibody testing for COVID-19.

15 Sep 2020

IRT technology provides more options to estimate facial temperatures with greater accuracy

Thermography has been a hot topic this year, due to the need for quicker diagnostics to detect and prevent the spread of COVID-19.

15 Sep 2020

Researchers detect significant amounts of DNA traps in lungs of deceased Covid-19 patients

A multidisciplinary team of researchers from the University of Liège (Belgium) has detected significant amounts of DNA traps in distinct compartments of the lungs of patients who died from Covid-19.

15 Sep 2020

3D bioengineered model could reveal new treatments for deadly lung disease

A 3D bioengineered model of lung tissue built by University of Michigan researchers is poking holes in decades worth of flat, Petri dish observations into how the deadly disease pulmonary fibrosis progresses.

14 Sep 2020

Should a COVID-19 vaccine be mandatory for children?

As the search for a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine continues, with some candidate vaccines nearing the completion Phase III clinical trials, a trio of experts weighs in with some sound reasoning as to whether any future vaccine should be considered mandatory for children. The viewpoint article is published in the journal JAMA Pediatrics in September 2020.

14 Sep 2020

International trial of blood thinners for COVID-19 treatment begins

These trials, known as ACTIV-4 Antithrombotics, are part of the three planned adaptive trials in this area of clinical research, included in the Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) initiative. They are expected to yield new data on the safety and efficacy of these drugs in the treatment of active and convalescent COVID-19 treatment.

13 Sep 2020

Climatic changes may potentially impact COVID-19 pandemic

A recent epidemiological study by Princeton University researchers suggests that the severity of coronavirus disease 2019 (COVID-19) outbreak during the winter season depends on the susceptibility of the population to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-induced infection as well as the effectiveness of non-pharmaceutical control measures applied to control the virus spread.

13 Sep 2020

India's whole-virion inactivated SARS-CoV-2 vaccine shows promise

Researchers in India have conducted a preclinical study demonstrating the safety and efficacy of a new candidate vaccine for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent that causes coronavirus disease 2019 (COVID-19).

13 Sep 2020

Switching antiseptics halves the risk of infection after surgery

Surgeons could dramatically reduce the risk of infection after an operation by simply changing the antiseptic they use.

12 Sep 2020

Effective, simple, safe self-amplifying RNA vaccines

A recent review paper in the journal Current Opinion in Virology in September 2020 shows how a new generation of RNA vaccines called self-amplifying RNA vaccines are more potent than conventional mRNA vaccines and could hold the key to the global production of cost-effective potent COVID-19 vaccines.

11 Sep 2020

Alternative UK air travel guidance likely needed to address COVID-19

Researchers have said that the UK guidance on preventing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from being imported via air travel does prevent a significant proportion of infectious travelers from putting people at risk of coronavirus disease 2019 (COVID-19).

10 Sep 2020

Parkinson's disease drug may improve vision in patients with age-related macular degeneration

Investigators have determined that treating patients with an advanced form of age-related macular degeneration (AMD) with levodopa, a safe and readily available drug commonly used to treat Parkinson's disease, stabilized and improved their vision.

10 Sep 2020

Robotic exosuit shows promising results in individuals undergoing post-stroke rehabilitation

A team of U.S. researchers published the results of a multi-center, single-arm trial of the ReWalk ReStore™ for gait training in individuals undergoing post-stroke rehabilitation.

10 Sep 2020

Efficacy News and Research

New York City’s initial lockdown reduced coronavirus spread by 70 percent, study says

Candidate monoclonal antibody shows hope as COVID-19 treatment

NTU-incubated start-up plans clinical trial of new slow-release pill for Parkinson’s disease

Curi Bio Announces Mantarray™ Platform for Analysis of 3D Engineered Muscle Tissues for Discovery of New Therapeutics

Pfizer's anti-viral 3CL protease inhibitor shows antiviral potential against SARS-CoV-2

Can amodiaquine short circuit this pandemic?

3D cluster of cells could enhance myocardial repair

New antibody assay for COVID-19 promises sensitive mass-scale detection

IRT technology provides more options to estimate facial temperatures with greater accuracy

Researchers detect significant amounts of DNA traps in lungs of deceased Covid-19 patients

3D bioengineered model could reveal new treatments for deadly lung disease

Should a COVID-19 vaccine be mandatory for children?

International trial of blood thinners for COVID-19 treatment begins

Climatic changes may potentially impact COVID-19 pandemic

India's whole-virion inactivated SARS-CoV-2 vaccine shows promise

Switching antiseptics halves the risk of infection after surgery

Effective, simple, safe self-amplifying RNA vaccines

Alternative UK air travel guidance likely needed to address COVID-19

Parkinson's disease drug may improve vision in patients with age-related macular degeneration

Robotic exosuit shows promising results in individuals undergoing post-stroke rehabilitation

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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