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MSK scientists discover epigenetic mechanism promoting breast cancer

Researchers from Memorial Sloan Kettering Cancer Center (MSK) have identified, for the first time, an epigenetic mechanism promoting breast cancer.

24 Mar 2017

Thermo Fisher Scientific collaborates with CGT Catapult to create seamless cell and gene therapy supply chain

To help address the challenges surrounding supply chain management for cell and gene therapy around the globe, Thermo Fisher Scientific, the world leader in serving science, today announced a collaboration with the Cell and Gene Therapy Catapult to provide developers with both the manufacturing capability and distribution, logistics, and storage capacity needed to create a seamless supply chain to accelerate cell and gene therapy development and commercialsation.

From Thermo Fisher Scientific Inc. 24 Mar 2017

New clinical approach offers hope for patients with aggressive brain cancer

Being diagnosed with a malignant brain tumor is devastating news for patients and their loved ones. Whereas some types of tumor respond well to treatment, others such as glioblastomas - the most common and aggressive brain tumors - are known to recur and progress within short times from the diagnosis.

23 Mar 2017

PRECISION Panc project aims to develop personalised treatments for pancreatic cancer patients

The development of new treatments for pancreatic cancer is set to be transformed by a network of clinical trials, aiming to find the right trial for the right patient, after a £10 million investment from Cancer Research UK.

23 Mar 2017

FDA grants accelerated approval to new drug for treatment of rare form of skin cancer

The U.S. Food and Drug Administration today granted accelerated approval to Bavencio (avelumab) for the treatment of adults and pediatric patients 12 years and older with metastatic Merkel cell carcinoma (MCC), including those who have not received prior chemotherapy.

23 Mar 2017

Intratumoral vaccination prolongs survival in mouse model of early stage resected pancreatic cancer

Building on their previous research focusing on vaccination within a tumor (intratumoral) for the most common form of pancreatic cancer, investigators from Rutgers Cancer Institute of New Jersey and Rutgers Robert Wood Johnson Medical School have shown that in a mouse model of early stage resected pancreatic cancer, intratumoral vaccination induces an anti-tumor response that results in a significant improvement in overall survival.

23 Mar 2017

Study shows safety of Schwann cell transplantation for treating subacute thoracic spinal cord injury

A Phase I clinical trial that targeted individuals with new onset paraplegia to evaluate the safety of transplanting their own potentially neuroprotective Schwann cells into a trauma-induced spinal cord lesion showed no evidence of adverse effects after 1 year.

22 Mar 2017

Study to assess effectiveness of two OTC medications for treating alcoholism in bipolar patients

Researchers have long wondered if medications could treat alcohol abuse. Ihsan Salloum, M.D., chief of the Division of Alcohol and Drug Abuse at the University of Miami Miller School of Medicine, hopes to answer that question in part with a new clinical trial with E. Sherwood Brown, M.D., Ph.D., at UT Southwestern Medical Center in Dallas.

22 Mar 2017

FDA approves drug as add-on treatment for Parkinson's disease patients

The U.S. Food and Drug Administration today approved Xadago (safinamide) tablets as an add-on treatment for patients with Parkinson's disease who are currently taking levodopa/carbidopa and experiencing "off" episodes.

21 Mar 2017

Treatment with interferon may ease symptoms of Ebola patients

A pilot study of a class of drugs used to treat hepatitis and some forms of multiple sclerosis has been shown for the first time to ease symptoms of Ebola patients, while also increasing their survival.

21 Mar 2017

Penn scientists discover method that appears to provide early warning of transplant rejection

Approximately 30,000 organ transplants occur in the United States each year. However, between 20 and 50 percent—depending on the organ type—of the transplanted organs fail within five years, most often because the recipient's immune system attacks, or "rejects," the donated organ.

21 Mar 2017

Oral sprays, topical methods can be easier option to guarantee vitamin and mineral absorption, says expert

Many people don’t realise that how they take their vitamin and mineral supplements is just as important as what they take.

From BetterYou Ltd 21 Mar 2017

New gene-silencing drugs cut cholesterol levels by half in early research

The first in a new class of gene-silencing drugs, known as inclisiran, has been shown to halve cholesterol levels in patients at risk of cardiovascular disease.

21 Mar 2017

Supplemental use of vitamin E and selenium did not forestall dementia, study finds

Antioxidant supplements vitamin E and selenium - taken alone or in combination - did not prevent dementia in asymptomatic older men, according to a study published online by JAMA Neurology.

20 Mar 2017

Early treatment with stem cells can safely help recovery in stroke patients, study shows

A multicenter trial looking at whether a single dose of millions of adult, bone-marrow-derived stem cells can aid stroke recovery indicates it's safe and well-tolerated by patients but may not significantly improve their recovery within the first three months, researchers report.

20 Mar 2017

Research: Surgical approaches may not offer added benefit to patients with tennis elbow

Surgical approaches to treating tennis elbow may not offer additional benefit to patients, as discussed in research presented at the American Orthopaedic Society for Sports Medicine's Specialty Day in San Diego.

20 Mar 2017

NeoGenomics, Definiens expand alliance to develop novel biomarker assays for clinical trials and testing

NeoGenomics, Inc., a leading provider of cancer-focused genetic testing services, and Definiens, the leader in Tissue Phenomics solutions from biomarker discovery to meaningful diagnostics, today announced that they have expanded their alliance to develop and automate the analysis of new biomarker assays for clinical trials and routine clinical testing.

20 Mar 2017

Clinical Trial News and Research

MSK scientists discover epigenetic mechanism promoting breast cancer

Thermo Fisher Scientific collaborates with CGT Catapult to create seamless cell and gene therapy supply chain

New clinical approach offers hope for patients with aggressive brain cancer

PRECISION Panc project aims to develop personalised treatments for pancreatic cancer patients

FDA grants accelerated approval to new drug for treatment of rare form of skin cancer

Intratumoral vaccination prolongs survival in mouse model of early stage resected pancreatic cancer

Study shows safety of Schwann cell transplantation for treating subacute thoracic spinal cord injury

Study to assess effectiveness of two OTC medications for treating alcoholism in bipolar patients

FDA approves drug as add-on treatment for Parkinson's disease patients

Treatment with interferon may ease symptoms of Ebola patients

Penn scientists discover method that appears to provide early warning of transplant rejection

Oral sprays, topical methods can be easier option to guarantee vitamin and mineral absorption, says expert

New gene-silencing drugs cut cholesterol levels by half in early research

Supplemental use of vitamin E and selenium did not forestall dementia, study finds

Early treatment with stem cells can safely help recovery in stroke patients, study shows

Research: Surgical approaches may not offer added benefit to patients with tennis elbow

NeoGenomics, Definiens expand alliance to develop novel biomarker assays for clinical trials and testing

Treating clogged arteries after heart attack improves outcomes, helps avoid subsequent procedures

Biomarker blood test detects recurrences of lung cancer before conventional imaging methods

Clinical study to examine whether antibiotics can be safe, effective alternative to appendectomy

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