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Convalescent plasma fails to improve outcome of COVID-19 in India

A new study based in India and published on the medRxiv preprint server explores the role of convalescent plasma (CP) in the treatment of moderate COVID-19 within the limitations on resources faced in a developing country.

9 Sep 2020

Pfizer, BioNTech COVID-19 vaccine candidate shows promise in preclinical study

Researchers in the United States and Germany have conducted a study demonstrating the preclinical efficacy of a new candidate vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent that causes coronavirus disease 2019 (COVID-19).

9 Sep 2020

Spironolactone may be safe to treat female pattern hair loss in breast cancer survivors

Spironolactone is not associated with increased risk of female breast cancer recurrence, according to research from the George Washington University Department of Dermatology.

9 Sep 2020

AstraZeneca COVID-19 vaccine trial paused due to suspected adverse reaction

The coronavirus disease (COVID-19) pandemic is rippling across the globe, with over 27.47 million reported cases. With the vast spread of the virus, scientists are racing to gain the approval of candidate vaccines against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19 disease and Multisystem Inflammatory Syndrome in Children (MIS-C).

8 Sep 2020

Tel Aviv University receives philanthropic grant from 3M for COVID-19 vaccine research

Science-based technology company 3M has awarded a significant philanthropic research grant of $400,000 to the Shmunis School of Biomedicine and Cancer Research at Tel Aviv University to advance scientific knowledge in the global response to the COVID-19 pandemic.

8 Sep 2020

Nanotechnological drug delivery system enhances the effectiveness of melanoma treatment

Researchers at Tel Aviv University, led by Prof. Ronit Satchi-Fainaro of TAU's Department of Physiology and Pharmacology at the Sackler School of Medicine, have developed an innovative nanotechnological drug delivery system that significantly enhances the effectiveness of treatment for the aggressive skin cancer melanoma.

8 Sep 2020

Focal high-intensity focused ultrasound ablation is an effective treatment for prostate cancer

For some prostate cancer patients, radical treatment (surgery or radiation) are treatment standards. However, these procedures may cause side effects including urinary incontinence or impotency.

8 Sep 2020

First 'plug and play' brain prosthesis demonstrated in a person with paralysis

In a significant advance, UC San Francisco Weill Institute for Neurosciences researchers working towards a brain-controlled prosthetic limb have shown that machine learning techniques helped an individual with paralysis learn to control a computer cursor using their brain activity without requiring extensive daily retraining, which has been a requirement of all past brain-computer interface efforts.

7 Sep 2020

Study shows how genetic data can be used to prioritize drug targets for complex diseases

An innovative genetic study of blood protein levels, led by researchers in the MRC Integrative Epidemiology Unit at the University of Bristol, has demonstrated how genetic data can be used to support drug target prioritisation by identifying the causal effects of proteins on diseases.

7 Sep 2020

Probiotics may help manage obesity in younger population

Probiotics may help children and adolescents with obesity lose weight when taken alongside a calorie-controlled diet, according to a study being presented at e-ECE 2020.

7 Sep 2020

Early-phase Russian trials reveal safety and immunogenicity of two formulations of a two-part vaccine

Results from two early-phase Russian non-randomised vaccine trials (Sputnik V) in a total of 76 people are published today in The Lancet, finding that two formulations of a two-part vaccine have a good safety profile with no serious adverse events detected over 42 days, and induce antibody responses in all participants within 21 days.

5 Sep 2020

Spike-based priming leads to high neutralizing activity in animal models

A new report by researchers at the University of Melbourne and published on the preprint server bioRxiv in September 2020 reports on the use of a two-protein two-dose vaccine regimen and its immunogenicity in two animal models.

4 Sep 2020

D614G spike mutation increases infectivity of SARS-CoV-2 and neutralization susceptibility

As the COVID-19 pandemic progresses, it is crucial to track the viral changes in order to link the clinical and epidemiological features of the disease with these mutations. A new study published on the preprint server bioRxiv* in September 2020 reports on a common severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mutation, D614G, and its effects on the virus.

4 Sep 2020

CRISPR-based system suppresses genes related to AAV antibody production

Gene therapy generally relies on viruses, such as adeno-associated virus (AAV), to deliver genes into a cell. In the case of CRISPR-based gene therapies, molecular scissors can then snip out a defective gene, add in a missing sequence or enact a temporary change in its expression, but the body's immune response to AAV can thwart the whole endeavor.

4 Sep 2020

COVID-19 vaccine candidate protects animals against SARS-CoV-2

Most people with COVID-19 have relatively mild disease, but a subset of people develop severe pneumonia and respiratory failure, potentially leading to death.

3 Sep 2020

Phase 3 study to test efficacy of new treatment for pediatric acute-onset neuropsychiatric syndrome

Octapharma has launched a phase 3, multi-center superiority study to compare the effectiveness of PANZYGA (immune globulin intravenous, human - ifas) 10% Liquid Preparation versus placebo in patients with pediatric acute-onset neuropsychiatric syndrome (PANS).

3 Sep 2020

Ellipsys Vascular Access System reduces time for dialysis treatments

The Ellipsys Vascular Access System reduces the time before patients with kidney failure can start lifesaving dialysis treatments, while requiring fewer secondary procedures, according to a new study led by interventional radiologist Jeffrey Hull, M.D., of Richmond Vascular Center.

3 Sep 2020

Nasal sprays are a known remedy for preventing opioid overdose deaths

Between 250 and 270 people die each year from heroin or opioid overdoses in Norway. In the EU, thousands die. European users now have a better option available for helping each other.

3 Sep 2020

Reformulated generic drug could offer a cost-effective way to accelerate recovery, prevent hospitalizations

Reformulated and patented version of well-known generic drug could prove to be a quick, safe and cost-effective way to accelerate recovery and prevent hospitalizations.

3 Sep 2020

Lysin-based antibacterial agent can help treat drug-resistant bacterial infections

The Centers for Disease Control and Prevention (CDC) has prioritized finding effective treatment of Methicillin-resistant Staphylococcus aureus (MRSA), one of the most common bacterial pathogens and the single most deadly drug-resistant bacteria in the United States.

3 Sep 2020

Efficacy News and Research

Convalescent plasma fails to improve outcome of COVID-19 in India

Pfizer, BioNTech COVID-19 vaccine candidate shows promise in preclinical study

Spironolactone may be safe to treat female pattern hair loss in breast cancer survivors

AstraZeneca COVID-19 vaccine trial paused due to suspected adverse reaction

Tel Aviv University receives philanthropic grant from 3M for COVID-19 vaccine research

Nanotechnological drug delivery system enhances the effectiveness of melanoma treatment

Focal high-intensity focused ultrasound ablation is an effective treatment for prostate cancer

First 'plug and play' brain prosthesis demonstrated in a person with paralysis

Study shows how genetic data can be used to prioritize drug targets for complex diseases

Probiotics may help manage obesity in younger population

Early-phase Russian trials reveal safety and immunogenicity of two formulations of a two-part vaccine

Spike-based priming leads to high neutralizing activity in animal models

D614G spike mutation increases infectivity of SARS-CoV-2 and neutralization susceptibility

CRISPR-based system suppresses genes related to AAV antibody production

COVID-19 vaccine candidate protects animals against SARS-CoV-2

Phase 3 study to test efficacy of new treatment for pediatric acute-onset neuropsychiatric syndrome

Ellipsys Vascular Access System reduces time for dialysis treatments

Nasal sprays are a known remedy for preventing opioid overdose deaths

Reformulated generic drug could offer a cost-effective way to accelerate recovery, prevent hospitalizations

Lysin-based antibacterial agent can help treat drug-resistant bacterial infections

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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