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Artificial intelligence can accurately predict prognosis of ovarian cancer patients

The artificial intelligence software, created by researchers at Imperial College London and the University of Melbourne, has been able to predict the prognosis of patients with ovarian cancer more accurately than current methods. It can also predict what treatment would be most effective for patients following diagnosis.

15 Feb 2019

Castration-resistant metastatic prostate cancer responds to combination of immune checkpoint inhibitors

Some patients with metastatic prostate cancer respond to a combination of immune checkpoint inhibitors after hormonal therapy and chemotherapy have failed, according to early results from a clinical trial led by investigators at The University of Texas MD Anderson Cancer Center presented today at the American Society of Clinical Oncology Genitourinary Cancers Symposium in San Francisco.

15 Feb 2019

Immune checkpoint molecule protects against future development of cancer

A research team at the University of Louisville has discovered that an immune checkpoint molecule they developed for cancer immunotherapy, also protects against future development of multiple types of cancer when administered by itself.

15 Feb 2019

New method for improved visualization of single-cell RNA- sequencing data

Like going from a pinhole camera to a Polaroid, a significant mathematical update to the formula for a popular bioinformatics data visualization method will allow researchers to develop snapshots of single-cell gene expression not only several times faster but also at much higher-resolution.

15 Feb 2019

New injury documentation tool may provide better evidence for elder abuse cases

An estimated 10 percent of older adults experience some form of abuse each year. However, the link between injuries and possible elder abuse may take months or years to establish and is often difficult to investigate due to poor documentation during prior medical visits.

15 Feb 2019

New study seeks to understand how colibactin causes cancer

For more than a decade, scientists have worked to understand the connection between colibactin, a compound produced by certain strains of E. coli, and colorectal cancer, but have been hampered by their inability to isolate the compound.

15 Feb 2019

WVU gynecologic oncologist investigates novel treatment for cervical and vaginal cancers

Cervical cancer can be insidious. Changes to the cervix are often detected with a pap smear, but for those with limited access to health care, cervical and vaginal cancers can go unnoticed for years--silently growing, spreading and invading other organs--and by the time they're detected, they may be so advanced that the patient's prognosis is poor and her treatment options few.

15 Feb 2019

Newly developed stem cell technologies show promise for treating PD patients

Cell replacement may play an increasing role in alleviating the motor symptoms of Parkinson's disease (PD) in future. Writing in a special supplement to the Journal of Parkinson's Disease, experts describe how newly developed stem cell technologies could be used to treat the disease and discuss the great promise, as well as the significant challenges, of stem cell treatment.

15 Feb 2019

Sausage mislabeling in Canada is down, new study finds

Sausage mislabelling in Canada is down, according to a new University of Guelph DNA barcoding study.

15 Feb 2019

Large-scale clinical trial begins to study liver transplantation between people with HIV

The first large-scale clinical trial to study liver transplantation between people with HIV has begun at clinical centers across the United States. The HOPE in Action Multicenter Liver Study will determine the safety of this practice by evaluating liver recipients for potential transplant-related and HIV-related complications following surgery.

15 Feb 2019

High-protein and low-calorie diet helps older adults lose weight safely, shows study

A high-protein, low-calorie diet helps older adults with obesity lose more weight, maintain more muscle mass, improve bone quality and lose "bad" fat, according to results from a new randomized controlled trial led by Wake Forest University researcher Kristen Beavers.

15 Feb 2019

HDL proteome behaves like a tiny Velcro ball that is rolling on surfaces

Cholesterol carried in high-density lipoprotein particles, or HDL cholesterol, has been dubbed the good cholesterol, because people whose HDL levels are high have a lower risk of developing heart disease. That link was first established in 1977 and has been confirmed over and over in epidemiological studies.

15 Feb 2019

Multi-sensory teaching method: Arithmetic and geometry can be studied through music, dance

Arithmetic and geometry can be studied through music and dance: this is the new multi-sensory teaching method identified by the European project WeDraw, coordinated by IIT-Istituto Italiano di Tecnologia.

15 Feb 2019

Suspicious spots on the lungs of children with rhabdomyosarcoma do not behave like metastases

Rhabdomyosarcoma is a malignant soft tissue tumor in the muscle tissue of children and adolescents. About 20 children are diagnosed with rhabdomyosarcoma per year in the Netherlands. "Metastases in these children are often found in the lungs," says professor Hans Merks of the Princess Máxima Center for Pediatric Oncology, who led the study.

15 Feb 2019

Moffitt researchers shed light on how CAR T cells function mechanistically

The scientific community has made great strides over the past decade in the development of a new class of cancer therapy called immunotherapy, a treatment that activates a patient's own immune system to target cancer cells.

15 Feb 2019

New mechanism for lateral inhibition of cells discovered

"The winner takes it all, the loser standing small" - that's not just true in the famous ABBA song, but also in animal development. Frequently, a group of cells starts out all being the same. But then one cell puts the brake on its neighbors, sending inhibitory signals that stop their differentiation. The "winning" cell, in the end, is different from its neighbors.

15 Feb 2019

Decolonization protocol after hospital discharge can prevent dangerous infections

Hospital patients who have methicillin-resistant Staphylococcus aureus can prevent future MRSA infections by following a standard bathing protocol after discharge, according to research results published in the February 14 issue of the New England Journal of Medicine.

15 Feb 2019

Researchers study animal venoms to identify new medicines for treating diseases

Animal venoms are the subject of study at research center based at the Butantan Institute in São Paulo. But in this case, the idea is not to find antidotes, but rather to use the properties of the venoms themselves to identify molecular targets of diseases and, armed with that knowledge, develop new compounds that can be used as medicines.

15 Feb 2019

Brain synchronization depends on the language of communication

Experts from the Basque research center BCBL have shown for the first time that the way in which the activity of two brains is connected depends on whether the dialogue takes place in the native language or in a foreign language.

15 Feb 2019

Platinum nanoparticles show selective toxicity against liver cancer cells

In recent years, the number of targeted cancer drugs has continued to rise. However, conventional chemotherapeutic agents still play an important role in cancer treatment.

15 Feb 2019

Research News and Research

Artificial intelligence can accurately predict prognosis of ovarian cancer patients

Castration-resistant metastatic prostate cancer responds to combination of immune checkpoint inhibitors

Immune checkpoint molecule protects against future development of cancer

New method for improved visualization of single-cell RNA- sequencing data

New injury documentation tool may provide better evidence for elder abuse cases

New study seeks to understand how colibactin causes cancer

WVU gynecologic oncologist investigates novel treatment for cervical and vaginal cancers

Newly developed stem cell technologies show promise for treating PD patients

Sausage mislabeling in Canada is down, new study finds

Large-scale clinical trial begins to study liver transplantation between people with HIV

High-protein and low-calorie diet helps older adults lose weight safely, shows study

HDL proteome behaves like a tiny Velcro ball that is rolling on surfaces

Multi-sensory teaching method: Arithmetic and geometry can be studied through music, dance

Suspicious spots on the lungs of children with rhabdomyosarcoma do not behave like metastases

Moffitt researchers shed light on how CAR T cells function mechanistically

New mechanism for lateral inhibition of cells discovered

Decolonization protocol after hospital discharge can prevent dangerous infections

Researchers study animal venoms to identify new medicines for treating diseases

Brain synchronization depends on the language of communication

Platinum nanoparticles show selective toxicity against liver cancer cells

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