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Good news for people with glycogen storage disease type Ia

A gene therapy treatment that restores a missing liver enzyme in test animals could provide a cure for a rare metabolic disorder in humans, according to Duke University Medical Center researchers.

13 Mar 2008

Caring for a family member with a serious heart ailment may increase your risk of cardiac disease

Researchers examined heart risk factors in family members of cardiac patients and found that those who provided all or most of a patient's care had higher levels of risk factors for heart disease than non-caregivers and those who reported higher caregiver strain after six months were more likely to be depressed than those who provided less or no care.

13 Mar 2008

Weight loss more effective than intensive insulin therapy for type 2 diabetics

Weight-loss and major lifestyle changes may be more effective than intensive insulin therapy for overweight patients with poorly controlled, insulin-resistant type 2 diabetes, according to a diabetes researcher at UT Southwestern Medical Center.

12 Mar 2008

Weight-loss more effective than intensive insulin therapy for type 2 diabetics, according to expert

11 Mar 2008

Poor sleep more dangerous for women

Researchers at Duke University Medical Center say they may have figured out why poor sleep does more harm to cardiovascular health in women than in men.

11 Mar 2008

Magnesium linked to lower risk for some strokes in male smokers

Male smokers who consume more magnesium appear to have a lower risk for cerebral infarction, a type of stroke that occurs when blood flow to the brain is blocked, according to a report in the March 10 issue of Archives of Internal Medicine.

11 Mar 2008

Refined carb diet increases risk of common diseases

Eating foods the body quickly converts into blood glucose - such as highly processed breakfast cereals and most white breads - leads to a greater risk of diabetes, heart disease and some types of cancer.

9 Mar 2008

New potential drug target for atherosclerosis

A nuclear receptor protein, known for controlling the ability of cells to burn fat, also exerts powerful anti-inflammatory effects in arteries, suppressing atherosclerosis in mice prone to developing the harmful plaques, according to new research by scientists at the Salk Institute for Biological Studies and the Harvard School of Public Health.

6 Mar 2008

Research in diabetes surgery suggests origins of disease

Growing evidence shows that surgery may effectively cure Type 2 diabetes -- an approach that not only may change the way the disease is treated, but that introduces a new way of thinking about diabetes.

5 Mar 2008

Diabetes is rapidly increasing globally, and Asian Indians have the highest prevalence

The incidence of type 2 diabetes is rising, especially in urbanized parts of the world where sedentary lifestyles and obesity abound.

1 Mar 2008

Low-fat better than low-carb diets for heart health

Low-fat diets are more effective in preserving and promoting a healthy cardiovascular system than low-carbohydrate, Atkins'-like diets, according to a new study by researchers at the Medical College of Wisconsin in Milwaukee.

1 Mar 2008

Intensive insulin therapy may be harmful to the critically ill

Doubt has been cast over the current practice of administering intensive insulin therapy to all critically ill patients, according to a study published this week in the open access journal Critical Care. In certain groups of patients it could even be harmful.

1 Mar 2008

AstraZeneca submits sNDA for SEROQUEL XR for treatment of major depressive disorder

AstraZeneca has announced the submission of a supplemental New Drug Application (sNDA) to the U.S. Food and Drug Administration (FDA) for once- daily SEROQUEL XR (quetiapine fumarate) Extended-Release Tablets to seek approval for the treatment of major depressive disorder (MDD) as monotherapy, adjunct therapy, and maintenance therapy in adult patients.

1 Mar 2008

Lilly knocked back by FDA on Zyprexa for schizophrenia treatment

Eli Lilly and Company has received a not approvable letter from the U.S. Food and Drug Administration for Zyprexa long-acting injection (olanzapine LAI) for the treatment and maintenance treatment of schizophrenia in adults, the company announced.

28 Feb 2008

Restricting insulin doses increases mortality risk in women with type 1 diabetes

A new study led by researchers at the Joslin Diabetes Center has found that women with type 1 diabetes who reported taking less insulin than prescribed had a three-fold increased risk of death and higher rates of disease complications than those who did not skip needed insulin shots.

28 Feb 2008

Overweight Hispanic children shown to have vascular inflammation

Overweight Hispanic children with normal blood glucose (sugar) levels showed elevated markers for blood vessel inflammation that may predispose them to developing both type 2 diabetes and cardiovascular disease, says a new study led by researchers from the Joslin Diabetes Center.

28 Feb 2008

Spinal cord injury may not increase risk of heart disease

Americans who live with spinal cord injury do not appear to be at greater risk of developing carbohydrate and lipid disorders such as insulin resistance, diabetes, impaired glucose tolerance, and high or low blood cholesterol levels - risk factors for heart disease - than able-bodied persons, according to a new evidence review by HHS' Agency for Healthcare Research and Quality.

27 Feb 2008

GP's databases could identify tens of thousands with undiagnosed diabetes in UK

Researchers who examined blood test records in a survey of over 3.6 million patient records held by UK GP surgeries have found thousands of cases of probable undiagnosed diabetes.

26 Feb 2008

New chemical tool kit manipulates mitochondria, reveals insights into drug toxicity

Why do nearly 1 million people taking cholesterol-lowering statins often experience muscle cramps? Why is it that in the rare case when a diabetic takes medication for intestinal worms, his glucose levels improve? Is there any scientific basis for the purported health effects of green tea?

26 Feb 2008