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Researchers use animal models to study how dysfunction of genes contributes to ASD risk

Autism Spectrum Disorder (ASD) is a neurological condition that affects approximately two percent of people around the world. Although several genes have been linked to multiple concurring conditions of ASD, the process that explains how specific genetic variants lead to behaviors characteristic of the disorder remains elusive.

27 May 2015

Six research teams awarded grant to accelerate discovery of new drugs for brain, nervous system disorders

CQDM, Brain Canada and the Ontario Brain Institute award close to $8.5M to six (6) multi-disciplinary and multi-provincial research teams across Canada to address unmet needs in neuroscience within their Focus on Brain strategic initiative. To this amount, $1.5M is added from the various research entities involved as in-kind contributions.

27 May 2015

Toronto researchers design simple chip for faster, easier detection of antibiotic-resistant bacteria

We live in fear of 'superbugs': infectious bacteria that don't respond to treatment by antibiotics, and can turn a routine hospital stay into a nightmare. A 2015 Health Canada report estimates that superbugs have already cost Canadians $1 billion, and are a "serious and growing issue." Each year two million people in the U.S. contract antibiotic-resistant infections, and at least 23,000 people die as a direct result.

27 May 2015

NYU chemists find that microRNA can serve as 'decoder ring' for understanding biological functions

MicroRNA can serve as a "decoder ring" for understanding complex biological processes, a team of New York University chemists has found. Their study, which appears in Proceedings of the National Academy of Sciences, points to a new method for decrypting the biological functions of enzymes and identifying those that drive diseases.

27 May 2015

Canadian researchers shed light on molecular dynamics of chronic pain

Chronic pain affects hundreds of millions of people worldwide and is a major cause of disability, causing more disability than cancer and heart disease. Canadian researchers, including Michael Salter at SickKids are shedding light on the molecular dynamics of chronic pain. They have uncovered a critical role for a class of cells present in the brain and spinal cord, called microglia, in pain.

27 May 2015

Researchers identify gene vital to production of pain-sensing neurons in humans

A gene essential to the production of pain-sensing neurons in humans has been identified by an international team of researchers co-led by the University of Cambridge. The discovery, reported today in the journal Nature Genetics, could have implications for the development of new methods of pain relief.

26 May 2015

Breakthrough in fight against rare kidney disease - Membranous Nephropathy

Scientists at The University of Manchester and Central Manchester University Hospitals NHS Foundation Trust have made a significant breakthrough in the fight against Membranous Nephropathy (MN) - a rare kidney disease which can lead to kidney failure.

22 May 2015

Omeros receives EMA CHMP positive opinion for Omidria for cataract, IOL replacement surgery

Omeros Corporation, a biopharmaceutical company committed to discovering, developing and commercializing small-molecule and protein therapeutics for both large-market as well as orphan indications targeting inflammation, coagulopathies and disorders of the central nervous system, today announced that the European Medicines Agency's (EMA's) Committee for Medicinal Products for Human Use (CHMP) has adopted a positive opinion for Omidria® (phenylephrine and ketorolac injection) 1%/0.3%.

22 May 2015

Chemical compound shows promise in treating rheumatoid arthritis

Montana State University researchers and their collaborators have published their findings about a chemical compound that shows potential for treating rheumatoid arthritis.

22 May 2015

Novel drug target identified for treating rheumatoid arthritis

Researchers at the La Jolla Institute for Allergy and Immunology, in collaboration with colleagues the University of California, San Diego, identified a novel drug target for the treatment of rheumatoid arthritis that focuses on the cells that are directly responsible for the cartilage damage in affected joints.

21 May 2015

Researchers find that blocking MCAM molecule could slow progression of multiple sclerosis

A drug that could halt the progression of multiple sclerosis may soon be developed thanks to a discovery by a team at the CHUM Research Centre and the University of Montreal. The researchers have identified a molecule called MCAM, and they have shown that blocking this molecule could delay the onset of the disease and significantly slow its progression.

21 May 2015

Non-coding micro RNA molecule may control chemotherapy resistance among ovarian cancer patients

A molecule that helps control gene expression may play a role in controlling chemotherapy resistance among patients with the most common form of ovarian cancer.

21 May 2015

Research may offer new targets for diagnosing, treating advanced prostate cancer

Researchers with the Indiana University School of Medicine have identified a molecule that promotes metastasis of advanced prostate cancer to the bone, an incurable condition that significantly decreases quality of life.

20 May 2015

Leeds scientists examine benefits of hyaluronic acid in helping improve IVF success rates

Scientists from the University of Leeds are investigating whether a molecule usually found in moisturisers and skin creams could improve IVF success rates in the UK.

20 May 2015

Johns Hopkins researchers identify new therapy to treat lung cancer

A multidisciplinary team led by Johns Hopkins researcher Venu Raman, Ph.D., with notable contributions from Guus Bol, Farhad Vesuna and Phuoc Tran of Johns Hopkins, has identified a new therapy for lung cancer, the most common cancer worldwide. The therapy has been in development for six years and involves a first-in-class molecule designed by the team.

20 May 2015

Cardiology researchers uncover new evidence that relates to increased risk of stroke

Cardiology researchers at The Queen Elizabeth Hospital have uncovered new evidence that relates to patients with new onset atrial fibrillation (AF) and their increased risk of stroke.

20 May 2015

New microscopy technique helps researchers to selectively visualize individual cells in living organism

Researchers at ETH Zurich's Department of Biosystems Science and Engineering in Basel have developed a new microscopy technique that enables for the first time to selectively visualize individual cells within the complex, three-dimensional tissue of a living organism.

20 May 2015

Molecule News and Research

Researchers use animal models to study how dysfunction of genes contributes to ASD risk

Six research teams awarded grant to accelerate discovery of new drugs for brain, nervous system disorders

Toronto researchers design simple chip for faster, easier detection of antibiotic-resistant bacteria

NYU chemists find that microRNA can serve as 'decoder ring' for understanding biological functions

Canadian researchers shed light on molecular dynamics of chronic pain

Researchers identify gene vital to production of pain-sensing neurons in humans

Breakthrough in fight against rare kidney disease - Membranous Nephropathy

Omeros receives EMA CHMP positive opinion for Omidria for cataract, IOL replacement surgery

Chemical compound shows promise in treating rheumatoid arthritis

Novel drug target identified for treating rheumatoid arthritis

Researchers find that blocking MCAM molecule could slow progression of multiple sclerosis

Non-coding micro RNA molecule may control chemotherapy resistance among ovarian cancer patients

Research may offer new targets for diagnosing, treating advanced prostate cancer

Leeds scientists examine benefits of hyaluronic acid in helping improve IVF success rates

Johns Hopkins researchers identify new therapy to treat lung cancer

Cardiology researchers uncover new evidence that relates to increased risk of stroke

New microscopy technique helps researchers to selectively visualize individual cells in living organism

Promising preliminary results for AKB-9778 in diabetic macular oedema

Scientists identify new molecules that destroy cancer cells, save healthy ones

Researchers make major step toward finding target to combat drug-resistant neuroblastoma

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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