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New DNA repair vehicle used to fix a common genetic cause of hereditary kidney disease

Genetic mutations which cause a debilitating hereditary kidney disease affecting children and young adults have been fixed in patient-derived kidney cells using a potentially game-changing DNA repair-kit. The advance developed by University of Bristol scientists is published in Nucleic Acids Research.

29 Jul 2022

Celebrating the role of aspirin as chemopreventative agent against cancer

A special edition issue of the Aspirin Summaries has been published '125 years of aspirin - the role of aspirin in cancer' issue 2022.

29 Jul 2022

Plant-based dietary alternatives to animal products offer a healthier and more sustainable solution

Plant-based dietary alternatives to animal products are better for the environment and for human health when compared with the animal products they are designed to replace, say the authors of a new study.

29 Jul 2022

NSF grant awarded to Zhang for producing muscle fiber with synthetic biology approach

Fuzhong Zhang, professor of energy, environmental and chemical engineering at the McKelvey School of Engineering, has developed a synthetic biology platform to produce muscle fibers that are strong, tough and can absorb energy in ways very similar to the real thing.

29 Jul 2022

RINVOQ® (upadacitinib) Approved by European Commission as an Oral Treatment for Adults with Active Non-Radiographic Axial Spondyloarthritis

With this approval, RINVOQ® is the first and only Janus Kinase inhibitor approved to treat patients across the spectrum of axial spondyloarthritis (nr-axSpA and ankylosing spondylitis) in the EU.

From AbbVie 29 Jul 2022

SARS-CoV-2 spike subunit 2–targeted vaccine could more effectively combat all human coronaviruses

In a new study, researchers evidenced that the S2 subunit of SARS-CoV-2 spike (S) could be an integral component of a pan-coronavirus vaccine.

29 Jul 2022

Tannins as therapeutic agents against SARS-CoV-2

Researchers reviewed tannins as therapeutic agents against SARS-CoV-2.

29 Jul 2022

Proteomics profiling of COVID-19 patients identifies dysregulated proteins and pathways

Researchers assessed the impact of SARS-CoV-2 infection and severity on coronary and Alzheimer’s disease pathways.

29 Jul 2022

Ultra-precise gene therapy technologies could edit or silence faulty genes causing fatal heart diseases

An injectable cure for inherited heart muscle conditions that can kill young people in the prime of their lives could be available within a few years, after an international team of researchers were announced as the winners of the British Heart Foundation's Big Beat Challenge.

29 Jul 2022

Modifi Bio comes up with a new technology to combat cancer cells with DNA modification

Modifi Biosciences announced today that the journal Science has published a critical study validating the company's novel oncology platform based on new classes of molecules that exploit tumor-associated DNA repair defects through direct cancer cell DNA modification.

29 Jul 2022

New glioma drug may represent a paradigm for designing therapeutics exploiting specific DNA repair

A new class of glioma drugs exploits tumors that lack the DNA repair enzyme MGMT; the drugs lead to the generation of cytotoxic DNA and selectively kill tumor cells without the risk of resistance, researchers report.

29 Jul 2022

Study uncovers the crucial roles of kinesins during the malaria parasite life cycle

Scientists at the University of Nottingham have made a major breakthrough in understanding how malaria parasites divide and transmit the disease, which could be a major step forwards in helping to prevent one of the biggest killer infections in the world.

29 Jul 2022

Study investigates the combined effects of aging and HIV-1 Tat expression in mice

A new research paper was published in Aging ("Aging (Albany NY)" by Medline/PubMed, "Aging-US" by Web of Science) Volume 14, Issue 13, entitled, "Age-related neuroendocrine, cognitive, and behavioral co-morbidities are promoted by HIV-1 Tat expression in male mice."

29 Jul 2022

New breakthrough shows antimicrobial resistance is more evolved than previously recognized

Researchers have discovered a significant and previously unknown mechanism that many bacteria use to resist antibiotics.

29 Jul 2022

Moderna COVID vaccine is more effective in older and sicker veterans over time

Researchers report the higher effectiveness of the Moderna COVID-19 vaccine as compared to the Pfizer COVID-19 vaccine.

28 Jul 2022

Researchers discover cell signaling pathway responsible for the development of esophageal cancers

Of the roughly 20,000 people in the U.S. diagnosed with esophageal cancer this year, just 4,000 are likely to still be alive in 2027.

28 Jul 2022

Study highlights impaired ketogenesis as a potential confounder of severe COVID-19

In severe Covid-19 patients, the metabolism produces insufficient amounts of certain energy-rich compounds called ketone bodies. However, these energy carriers are needed by two important cell types in the immune system in order to fight the virus effectively.

28 Jul 2022

The global mutation landscape of the SARS-CoV-2 non-structural protein 1

Researchers describe the evolution of the SARS-CoV-2 non-structural protein 1 (NSP1).

28 Jul 2022

Scientists discover a new set of chemical reactions to generate amino acids and nucleic acids

Four billion years ago, the Earth looked very different than it does today, devoid of life and covered by a vast ocean. Over the course of millions of years, in that primordial soup, life emerged. Researchers have long theorized how molecules came together to spark this transition.

28 Jul 2022

The bat-virus relationship examined

A new study examines the role of bats as reservoirs of several viruses and the factors that contribute to the emergence of these viruses.

28 Jul 2022

Protein C News and Research

New DNA repair vehicle used to fix a common genetic cause of hereditary kidney disease

Celebrating the role of aspirin as chemopreventative agent against cancer

Plant-based dietary alternatives to animal products offer a healthier and more sustainable solution

NSF grant awarded to Zhang for producing muscle fiber with synthetic biology approach

RINVOQ® (upadacitinib) Approved by European Commission as an Oral Treatment for Adults with Active Non-Radiographic Axial Spondyloarthritis

SARS-CoV-2 spike subunit 2–targeted vaccine could more effectively combat all human coronaviruses

Tannins as therapeutic agents against SARS-CoV-2

Proteomics profiling of COVID-19 patients identifies dysregulated proteins and pathways

Ultra-precise gene therapy technologies could edit or silence faulty genes causing fatal heart diseases

Modifi Bio comes up with a new technology to combat cancer cells with DNA modification

New glioma drug may represent a paradigm for designing therapeutics exploiting specific DNA repair

Study uncovers the crucial roles of kinesins during the malaria parasite life cycle

Study investigates the combined effects of aging and HIV-1 Tat expression in mice

New breakthrough shows antimicrobial resistance is more evolved than previously recognized

Moderna COVID vaccine is more effective in older and sicker veterans over time

Researchers discover cell signaling pathway responsible for the development of esophageal cancers

Study highlights impaired ketogenesis as a potential confounder of severe COVID-19

The global mutation landscape of the SARS-CoV-2 non-structural protein 1

Scientists discover a new set of chemical reactions to generate amino acids and nucleic acids

The bat-virus relationship examined

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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