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Highly specialized T cells remain in blood 20 months after COVID-19

researchers analyze T-cell reactivity following recovery from COVID-19.

27 Jul 2022

Specific area of SARS-CoV-2 spike protein found to be a promising target for pan-coronavirus vaccine

Researchers at the Francis Crick Institute have shown that a specific area of the SARS-CoV-2 spike protein is a promising target for a pan-coronavirus vaccine that could offer some protection against new virus variants, common colds, and help prepare for future pandemics.

27 Jul 2022

Study finds specific molecular barriers to SARS-CoV-2 replication in bat cells

Bat cells have specific molecular barriers to deal with SARS-CoV-2 replication, according to a study published in Journal of Virology —publication of the American Society of Microbiology— which includes the participation of Jordi Serra-Cobo, lecturer of the Faculty of Biology and the Biodiversity Research Institute (IRBio) of the University of Barcelona and expert on ecoepidemiological studies.

27 Jul 2022

'Western style' diet high in fat and sugar can negatively affect breast milk and baby's health

A diet high in sugar and fat such as burgers, fries and fizzy drinks can negatively affect a new mother's breast milk and baby's health even before the child is conceived.

27 Jul 2022

Investigating an effective linear deoxyribonucleic acid COVID-19 vaccine option for domestic cats

In a new study, investigators studied a linear deoxyribonucleic acid (linDNA) SARS-CoV-2 vaccine option in felines.

27 Jul 2022

Increased resistance to human interferons could be a potential driver of SARS-CoV-2 evolution

Researchers compared the potency of 17 human interferons (IFNs) against multiple SARS-CoV-2 variants.

27 Jul 2022

Study shows SARS-CoV-2 impairs interferon production through NSP2-induced repression of mRNA translation

Researchers discovered a SARS-CoV-2 non-structural protein 2 (NSP2)-mediated mechanism by which it suppresses the production of interferon-beta (IFN-β) in host cells.

27 Jul 2022

Scientists receive $3.9 million NIH grant to eradicate HIV from the brain

Finding a cure for HIV has been extremely difficult, in part because the virus hides from antiretroviral treatments in one of the hardest places to reach: the brain.

27 Jul 2022

New method could lead to more efficient production of next-generation antibiotics

An international team of researchers has developed a method for altering one class of antibiotics, using microscopic organisms that produce these compounds naturally.

27 Jul 2022

Study shows the emerging Omicron sublineage BA.2.75 does not show greater immune evasion than BA.5

Researchers assessed the sensitivity of SARS-CoV-2 Omicron BA.2.75 variant to neutralizing antibodies.

27 Jul 2022

Novel compound inhibits SARS-CoV-2 replication by binding a genome target

Researchers assessed the biodistribution and safety of SBCoV202, a novel antiviral agent based on antisense technology that can specifically and effectively bind to the SARS-CoV-2 genome target to inhibit SARS-CoV-2 replication.

27 Jul 2022

Scientists explore associations between SARS-CoV-2 neutralizing antibodies and receptor-binding domain-selective proliferative memory CD4 T cells

Researchers depicted the correlations between receptor-binding domain (RBD)-selective proliferative memory CD4 T cells and neutralizing antibodies in COVID-19 vaccinees and convalescent patients.

27 Jul 2022

Temporal changes in CD4 T-lymphocyte dynamics upon immunization against SARS-CoV-2 spike protein

Researchers assessed changes in CD4 T-lymphocyte temporal dynamics by evaluating T-lymphocyte responses to SARS-CoV-2 S using Foxp3-Tocky mice and Nr4a3-Tocky mice.

27 Jul 2022

The neutralizing antibody response in mRNA vaccinated and boosted healthcare workers against major circulating SARS-CoV-2 Omicron subvariants

Researchers assessed the duration of the neutralizing antibody responses after SARS-CoV-2 mRNA booster vaccination.

27 Jul 2022

Study estimates prevalence of SARS-CoV-2 omicron breakthrough infections in South Africa

Scientists have described the prevalence of vaccine breakthrough SARS-CoV-2 infection in South Africa during the period of delta and omicron circulation.

27 Jul 2022

Nasal spray highly effective against HIV and SARS-CoV-2 in animal models

The intranasal delivery of amph-protein vaccines is a potential approach to elicit a mucosal immune response against many infectious diseases.

26 Jul 2022

Three doses of Novavax vaccine effective against Omicron subvariants

Researchers report that Novavax COVID-19 vaccine triggers robust neutralization against SARS-CoV-2 Omicron subvariants.

26 Jul 2022

CDC: Novavax's COVID-19 vaccine can be used as another primary series option for adults

Today, CDC Director Rochelle P. Walensky, M.D., M.P.H., endorsed the CDC Advisory Committee on Immunization Practices' (ACIP) recommendation that Novavax's COVID-19 vaccine be used as another primary series option for adults ages 18 years and older.

26 Jul 2022

How has vaccination shaped the global evolutionary trajectory of SARS-CoV-2?

In a new study, researchers developed a maximum likelihood model to capture severe acute respiratory syndrome coronavirus 2 evolutionary dynamics in multiple geographical regions.

26 Jul 2022

SLU and industry partners report the first effective drug to treat rare, genetic liver disease

Researchers at Saint Louis University's School of Medicine, in collaboration with Arrowhead Pharmaceuticals and Takeda Pharmaceuticals, report the first effective drug to treat a rare, genetic liver disease that formerly could only be treated with a liver transplant.

26 Jul 2022

Protein C News and Research

Highly specialized T cells remain in blood 20 months after COVID-19

Specific area of SARS-CoV-2 spike protein found to be a promising target for pan-coronavirus vaccine

Study finds specific molecular barriers to SARS-CoV-2 replication in bat cells

'Western style' diet high in fat and sugar can negatively affect breast milk and baby's health

Investigating an effective linear deoxyribonucleic acid COVID-19 vaccine option for domestic cats

Increased resistance to human interferons could be a potential driver of SARS-CoV-2 evolution

Study shows SARS-CoV-2 impairs interferon production through NSP2-induced repression of mRNA translation

Scientists receive $3.9 million NIH grant to eradicate HIV from the brain

New method could lead to more efficient production of next-generation antibiotics

Study shows the emerging Omicron sublineage BA.2.75 does not show greater immune evasion than BA.5

Novel compound inhibits SARS-CoV-2 replication by binding a genome target

Scientists explore associations between SARS-CoV-2 neutralizing antibodies and receptor-binding domain-selective proliferative memory CD4 T cells

Temporal changes in CD4 T-lymphocyte dynamics upon immunization against SARS-CoV-2 spike protein

The neutralizing antibody response in mRNA vaccinated and boosted healthcare workers against major circulating SARS-CoV-2 Omicron subvariants

Study estimates prevalence of SARS-CoV-2 omicron breakthrough infections in South Africa

Nasal spray highly effective against HIV and SARS-CoV-2 in animal models

Three doses of Novavax vaccine effective against Omicron subvariants

CDC: Novavax's COVID-19 vaccine can be used as another primary series option for adults

How has vaccination shaped the global evolutionary trajectory of SARS-CoV-2?

SLU and industry partners report the first effective drug to treat rare, genetic liver disease

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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