Neuroscience News and Research

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Phase 2 RESONATE-17 study: IMBRUVICA (ibrutinib) improves survival in CLL patients with del 17p

Results from the Phase 2 RESONATE-17 (PCYC-1117) study show IMBRUVICA (ibrutinib) was associated with an 82.6 percent investigator-assessed overall response rate (ORR; the primary endpoint) and a 79 percent progression-free survival (PFS) rate at 12 months in people living with relapsed/refractory chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) who have a genetic mutation known as deletion 17p (del 17p).

9 Dec 2014

Study shows link between cardiac abnormalities, sudden unexpected death in epilepsy

Groundbreaking findings describing the link between cardiac abnormalities and sudden unexpected death in epilepsy (SUDEP) will be presented at the American Epilepsy Society's Annual Meeting in December.

7 Dec 2014

Scientists devise powerful algorithm to improve effectiveness of research technology harnessing RNAi

Scientists at Cold Spring Harbor Laboratory have devised a powerful algorithm that improves the effectiveness of an important research technology harnessing RNA interference, or RNAi.

7 Dec 2014

BUSM's Carmela Abraham receives 2014 Massachusetts Neuroscience Consortium Award

Carmela Abraham, PhD, professor of biochemistry and pharmacology at Boston University School of Medicine, was one of six recipients of this year's Massachusetts Neuroscience Consortium Award out of nearly 60 applicants. The grant was awarded to her for her work on multiple sclerosis and the role of the life extension protein Klotho in the limited repair of white matter in the disease.

7 Dec 2014

Researchers identify important neural mechanism responsible for certain chronic pain disorders

Pain typically has a clear cause-but not always. When a person touches something hot or bumps into a sharp object, it's no surprise that it hurts. But for people with certain chronic pain disorders, including fibromyalgia and phantom limb pain, a gentle caress can result in agony.

6 Dec 2014

University of Utah professor develops MORE intervention program for chronic pain patients

How can people who are dependent on prescription opioids reduce their cravings? Learn to enjoy other aspects of their lives.

6 Dec 2014

University of Miami researcher reveals association between 'salience processing' and brain disorders

How does the brain determine what matters? According to a new scientific article, a brain structure called the insula is essential for selecting things out of the environment that are "salient" for an individual, and dysfunction of this system is linked to brain disorders such as autism, psychosis and dementia.

5 Dec 2014

Abstinence-induced changes in the brain could help predict relapse in smokers

Quitting smoking sets off a series of changes in the brain that Penn Medicine researchers say may better identify smokers who will start smoking again—a prediction that goes above and beyond today's clinical or behavioral tools for assessing relapse risk.

5 Dec 2014

Hormone leptin increases blood pressure that occurs with weight gain

Leptin, a hormone that regulates the amount of fat stored in the body, also drives the increase in blood pressure that occurs with weight gain, according to researchers from Monash University and the University of Cambridge.

5 Dec 2014

TSRI scientists identify 'mechanoreceptor' protein that mediates sense of touch in mammals

A team led by biologists at The Scripps Research Institute has solved a long-standing mystery in neuroscience by identifying the "mechanoreceptor" protein that mediates the sense of touch in mammals.

5 Dec 2014

People with first-episode psychosis may benefit from medication treatment changes, study finds

Many patients with first-episode psychosis receive medications that do not comply with recommended guidelines for first-episode treatment, researchers have found. Current guidelines emphasize low doses of antipsychotic drugs and strategies for minimizing the side effects that might contribute to patients stopping their medication.

5 Dec 2014

New drug offers hope for victims of spinal cord injury

Scientist in the U.S have developed a drug that could help paralysed victims of spinal cord injury regain their ability to move.

4 Dec 2014

SPSP 2015 to feature symposia on social and personality psychology

The 16th Annual Convention of the Society for Personality and Social Psychology (SPSP) will bring together 3,500 scientists to share their latest research in 84 symposia and 2,256 posters.

4 Dec 2014

New chemical compound shows promise in restoring function lost to spinal cord injury

Case Western Reserve scientists have developed a new chemical compound that shows extraordinary promise in restoring function lost to spinal cord injury. The compound, which the researchers dubbed intracellular sigma peptide (ISP), allowed paralyzed muscles to activate in more than 80 percent of the animals tested.

4 Dec 2014

UAB research suggests potential therapeutic target for patients with frontotemporal dementia

Drugs that boost the function of a specific type of neurotransmitter receptor may provide benefit to patients with the second most common type of dementia, according to research by scientists at the University of Alabama at Birmingham published today in the Journal of Neuroscience.

4 Dec 2014

Researchers identify biochemical mechanism that could lead to 'chemo brain'

UNC School of Medicine researchers have found for the first time a biochemical mechanism that could be a cause of "chemo brain" - the neurological side effects such as memory loss, confusion, difficulty thinking, and trouble concentrating that many cancer patients experience while on chemotherapy to treat tumors in other parts of the body.

4 Dec 2014

UC Berkeley scientists reveal how humans have excelled at 'relational reasoning'

When it comes to getting out of a tricky situation, we humans have an evolutionary edge over other primates. Take, as a dramatic example, the Apollo 13 voyage in which engineers, against all odds, improvised a chemical filter on a lunar module to prevent carbon dioxide buildup from killing the crew.

4 Dec 2014

Tobacco smoke toxin could increase pain in people with spinal cord injury

A neurotoxin called acrolein found in tobacco smoke that is thought to increase pain in people with spinal cord injury has now been shown to accumulate in mice exposed to the equivalent of 12 cigarettes daily over a short time period.

4 Dec 2014

Researchers use MRI techniques to study consequences of anorexia nervosa on brain structure

Researchers from the Translational Developmental Neuroscience Lab led by Professor Stefan Ehrlich at the Department of Child and Adolescent Psychiatry and Psychotherapy of the University Hospital Carl Gustav Carus at the TU Dresden (Faculty of Medicine) used state-of-the-art magnetic resonance imaging (MRI) techniques to investigate the consequences of anorexia nervosa on brain structure.

3 Dec 2014

Oxford University Press plans to launch new open access journal in partnership with ASSC

Oxford University Press is delighted to announce that it is to launch a brand new Open Access journal, Neuroscience of Consciousness, in partnership with the Association for the Scientific Study of Consciousness.

3 Dec 2014

Neuroscience News and Research

Phase 2 RESONATE-17 study: IMBRUVICA (ibrutinib) improves survival in CLL patients with del 17p

Study shows link between cardiac abnormalities, sudden unexpected death in epilepsy

Scientists devise powerful algorithm to improve effectiveness of research technology harnessing RNAi

BUSM's Carmela Abraham receives 2014 Massachusetts Neuroscience Consortium Award

Researchers identify important neural mechanism responsible for certain chronic pain disorders

University of Utah professor develops MORE intervention program for chronic pain patients

University of Miami researcher reveals association between 'salience processing' and brain disorders

Abstinence-induced changes in the brain could help predict relapse in smokers

Hormone leptin increases blood pressure that occurs with weight gain

TSRI scientists identify 'mechanoreceptor' protein that mediates sense of touch in mammals

People with first-episode psychosis may benefit from medication treatment changes, study finds

New drug offers hope for victims of spinal cord injury

SPSP 2015 to feature symposia on social and personality psychology

New chemical compound shows promise in restoring function lost to spinal cord injury

UAB research suggests potential therapeutic target for patients with frontotemporal dementia

Researchers identify biochemical mechanism that could lead to 'chemo brain'

UC Berkeley scientists reveal how humans have excelled at 'relational reasoning'

Tobacco smoke toxin could increase pain in people with spinal cord injury

Researchers use MRI techniques to study consequences of anorexia nervosa on brain structure

Oxford University Press plans to launch new open access journal in partnership with ASSC

Neuroscience - Third Edition eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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