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Study could lead to new strategies for slowing the growth of glioblastoma

Researchers are hopeful that new strategies could emerge for slowing the growth and recurrence of the most common primary brain cancer in adults, glioblastoma, based on the results of a study published today in Cancer Research.

10 Jul 2019

Researchers pinpoint treatment target for rare liver cancer in adolescents, young adults

New findings show how a genetically aberrant, fused protein promotes a rare form of liver cancer in adolescents and young adults. The researchers also saw that a certain mix of drugs could target the fused protein and the enzymes that it recruits.

10 Jul 2019

Special blood test may predict relapse risk for breast cancer patients

A special blood test may one day predict if a newly diagnosed breast cancer patient will likely relapse years later, a City of Hope study suggests.

9 Jul 2019

Engineered stem cells offer new treatment for metastatic bone cancer

Engineered stem cells could help treat metastatic cancers in bone without killing normal surrounding bone.

9 Jul 2019

New class of cancer-killing agents shows promise in destroying cancer stem cells

Scientists at The University of Toledo investigating improvements to a commonly used chemotherapy drug have discovered an entirely new class of cancer-killing agents that show promise in eradicating cancer stem cells.

9 Jul 2019

Novel anticancer agents show promise to control tumor growth in nearly every cancer type

A gene called MYC has become one of the hottest targets for cancer researchers around the world. MYC is known to drive tumor growth in nearly all cancer types - but successfully targeting the gene has proven to be a challenge.

9 Jul 2019

Thioredoxin antioxidant could soon be used to improve cancer treatment

Researchers from Medical University of South Carolina (MUSC) have discovered the use of thioredoxin – a naturally occurring antioxidant to modulate T cells of the immune system. This may be a big step towards improving currently used immune therapies such as adoptive T-cell therapy (ACT) and hematopoietic stem cell transplantation (HSCT).

8 Jul 2019

New drug combination found to be effective against uveal melanoma in preclinical studies

Uveal melanoma is a very aggressive type of melanoma that affects the eye. It is a rare disorder, affecting an estimated 2,500 people in the United States each year.

8 Jul 2019

Could hormone therapy for prostate cancer increase the risk of Alzheimer’s disease?

Men who take hormone-blocking therapy (ADT) for prostate cancer may be at an increased risk of developing dementia and Alzheimer’s disease.

8 Jul 2019

Scientists discover rare autoimmune disease triggered by testicular cancer

A new autoimmune disease has been discovered that is triggered by testicular cancer. The condition is rare, but cases are growing.

8 Jul 2019

Common cold virus strain could be a breakthrough in bladder cancer treatment

Scientists in the UK have found a new way to treat bladder cancer, using a strain of one of the viruses that cause the common cold. The virus is called Coxsackie virus CVA21, and it was found to be oncolytic, or tumor-destroying.

8 Jul 2019

Researchers discover novel cancer-promoting molecular mechanism

A novel cancer-promoting molecular mechanism has been discovered by Pierluigi Scalia, M.D., Ph.D., with his co-workers at the Sbarro Institute for Cancer Research and Molecular Medicine, Division of Biology, Temple University, the Department of Medical Biotechnologies at University of Siena, Italy and the Italian non-profit research organization ISOPROG, in collaboration with the Center of Biocomputational Sciences, part of the College of Science and Technology in Philadelphia.

8 Jul 2019

New drug combinations and dosing schedules improve outlook in advanced colon cancer

Advanced colon cancer often spreads widely and may not respond to standard chemotherapy. In such a case, a novel combination of drugs and flexible dosing may help achieve a better outlook, as demonstrated by several new studies.

8 Jul 2019

Sports playbook can help generate more accurate prognoses for cancer patients

In this season of global soccer competitions and hotly contested political primaries, bookies and pundits are scouring every evolving scrap of information and sifting through mountains of data in an effort to predict the outcome of the next game or election.

4 Jul 2019

Using NMR to Study Protein Structure, Dynamics and Mechanisms

Fábio Almeida describes how NMR can be used to elucidate protein structure and how this data can be applied to human disease.

From Bruker BioSpin Group 4 Jul 2019

Study reports role of cancer gene in tumor microenvironment

The tumor microenvironment is a mix of fluids, immune cells and blood vessels which envelops the tumors. Interactions between tumor cells and the TME determine the progression and fate of tumors.

4 Jul 2019

Researchers use artificial intelligence to predict molecular classification of colorectal cancer

Treating physicians need information about the molecular subtype of the tumor if they are to provide targeted therapy for colorectal carcinoma.

4 Jul 2019

HER2-positive breast cancer may be treated with imprinted nanospheres

A particularly aggressive, metastasizing form of cancer, HER2-positive breast cancer, may be treated with nanoscopic particles “imprinted” with specific binding sites for the receptor molecule HER2.

4 Jul 2019

Findings suggest new ways to help the immune system fight pancreatic cancer

Findings published today in the journal Science Translational Medicine suggest that a type of white blood cell called tumor associated macrophages that have been deceived by pancreatic cancer cells into not attacking them can be "re-programmed" by a specially designed molecule that activates a protein found on their surfaces.

4 Jul 2019

Researcher finds possible strategy for killing cancer cells in children

In Belgium, there are 70,000 new adult cases of cancer every year, compared to 350 in children. Owing to lack of interest from pharmaceutical groups, treatments for pediatric cancers are developing much less rapidly than those for adults.

4 Jul 2019