B Cell News and Research

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Obesity strikes below the belt: Study reveals link between obesity and male infertility

The influence of obesity on male fertility is still under debate. In the present investigation, researchers scrutinized semen samples from both obese individuals and those of normal weight. The aim was to explore the relationship between obesity, the length of sperm telomeres, levels of mRNA associated with autophagy, and diverse semen characteristics.

29 May 2023

Energy drinks may stunt muscle repair, new study suggests

Energy drinks impede muscle regeneration and reduce physical performance. This study provided evidence of an inhibitory effect on myogenic differentiation and highlighted potential concerns for athletes and fitness enthusiasts.

29 May 2023

Artificial intelligence in sperm selection for assisted reproduction

Researchers summarize available evidence on the application of artificial intelligence and machine learning in sperm selection.

29 May 2023

Regulatory T cells lacking SRC-3 gene mediate long-lasting tumor eradication

Researchers at Baylor College of Medicine have discovered a crucial regulator of the anti-cancer immune response that could change the game in the fight against cancer.

29 May 2023

Study maps immune responses produced by COVID-19 vaccination in First Nations population

Published in Nature Immunology and Nature Briefing, the research is the first of its kind to decisively map immune responses produced by a COVID-19 vaccination in any First Nations populations.

29 May 2023

New pan-cancer T cell atlas provides a deeper understanding of complex tumor microenvironment

A new study led by researchers at The University of Texas MD Anderson Cancer Center, published today in Nature Medicine, provides a deeper understanding of the vast diversity of T cell states as well as their relationships and roles within the complex tumor microenvironment, bringing a fresh perspective to understanding immunotherapy efficacy in cancer.

29 May 2023

Novel assay for identifying individuals with synucleinopathies using serum samples

Synucleinopathies are a group of neurodegenerative diseases caused by the abnormal accumulation α-synuclein, a protein normally found in the brain and neurons. Incorrect folding of α-synuclein leads to formation of 'seeds', which attract more α-synuclein proteins to form larger clumps.

29 May 2023

Gene expression signature associated with rapid progression of type 1 diabetes

Researchers from Turku Bioscience Centre and InFLAMES Flagship at the University of Turku in Finland, have identified a gene expression signature that can predict the progression of type 1 diabetes.

29 May 2023

Novel treatment targets against natural killer/T-cell lymphoma identified

A team of researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore has discovered that a transcription factor, TOX2, was aberrantly increased in patients with Natural killer/T-cell lymphoma (NKTL).

29 May 2023

Passing on Polycystic Ovary Syndrome: Health risks for Male offspring of Women with PCOS

In this interview, we spoke to two researchers from the Karolinska Institutet about their latest work that investigated how PCOS can affect the health of future generations of men.

29 May 2023

Modest reduction in beta-amyloidogenic processing of APP may be a viable strategy to prevent Alzheimer's disease

A new study conducted by researchers at the University of Eastern Finland discovered that the APP A673T genetic variant, which protects against Alzheimer’s disease, alters levels of several proteins and peptides linked to amyloid-beta metabolism in human biofluids and cell culture models, including amyloid beta itself.

26 May 2023

2023 PCRF grant recipients announced for exploring new, safer treatments for pediatric cancers

The Pediatric Cancer Research Foundation, a nonproﬁt focused on transforming pediatric cancer care by accelerating research breakthroughs, today announced the 19 recipients of its 2023 research grants.

26 May 2023

New understanding of chemotherapeutic resistance in recurring ovarian cancer

A new editorial paper was published in Oncoscience (Volume 10) on May 11, 2023, entitled, "UPR-induced ovarian cancer cell fusion: a mechanism favoring drug resistance?"

26 May 2023

Study identifies a novel druggable signaling molecule involved in obesity and diabetes

More than 40% of Americans are considered obese, and the trend continues to grow. The treatments or preventive options for obesity and obesity-associated diseases are limited.

26 May 2023

Penn State researchers create first protein-based nano-computing agent

The first protein-based nano-computing agent that functions as a circuit has been created by Penn State researchers.

26 May 2023

Research could help develop better treatments for swallowing disorders

Sensory cells in the vagus nerve can detect and locate food in the esophagus. Their signals help transport the food onward to the stomach. Signal failure leads to swallowing disorders, say a team led by Carmen Birchmeier at the Max Delbrück Center.

26 May 2023

Phase 3 studies for rectal, brain, and kidney cancers to be presented by Dana-Farber researchers at ASCO 2023

Several phase 3 studies conducted by researchers from Dana-Farber Cancer Institute show promising results for patients with rectal, brain, and kidney cancers. The results of these studies, along with dozens of others led by Dana-Farber researchers, will be presented at the 2023 Annual Meeting of the American Society of Clinical Oncology (ASCO) in Chicago.

26 May 2023

B Cell News and Research

Obesity strikes below the belt: Study reveals link between obesity and male infertility

Energy drinks may stunt muscle repair, new study suggests

Artificial intelligence in sperm selection for assisted reproduction

Regulatory T cells lacking SRC-3 gene mediate long-lasting tumor eradication

Study maps immune responses produced by COVID-19 vaccination in First Nations population

New pan-cancer T cell atlas provides a deeper understanding of complex tumor microenvironment

Novel assay for identifying individuals with synucleinopathies using serum samples

Gene expression signature associated with rapid progression of type 1 diabetes

Novel treatment targets against natural killer/T-cell lymphoma identified

Passing on Polycystic Ovary Syndrome: Health risks for Male offspring of Women with PCOS

Modest reduction in beta-amyloidogenic processing of APP may be a viable strategy to prevent Alzheimer's disease

2023 PCRF grant recipients announced for exploring new, safer treatments for pediatric cancers

New understanding of chemotherapeutic resistance in recurring ovarian cancer

Study identifies a novel druggable signaling molecule involved in obesity and diabetes

Penn State researchers create first protein-based nano-computing agent

Research could help develop better treatments for swallowing disorders

Phase 3 studies for rectal, brain, and kidney cancers to be presented by Dana-Farber researchers at ASCO 2023

Hydrogen sulfide can be used to support photothermal therapy for cancer

Study highlights two strategies used by Salmonella to escape the human body's defenses

Defective proteins involved in ER-phagy can cause neurodegenerative diseases

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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