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Nanomedicine-based strategy enhances anti-PD1 therapy to eradicate PTEN-negative GBM

A nanomedicine-based strategy for chemo-immunotherapy (CIT) of glioblastoma (GBM), which has the worst prognosis among brain tumors, was successfully developed.

7 Aug 2020

Custom smartwatch tracks drug levels inside the body in real time

Engineers at the UCLA Samueli School of Engineering and their colleagues at Stanford School of Medicine have demonstrated that drug levels inside the body can be tracked in real time using a custom smartwatch that analyzes the chemicals found in sweat.

7 Aug 2020

How misinformation undermines Australia's COVID-19 response

The current global climate of misinformation and myths about the origin, cure of, and measures required to deal with the COVID-19 pandemic has mired public acceptance of and compliance with governmental interventions and personal precautions.

7 Aug 2020

Researchers use patient-specific tumor organoid to optimize chemotherapy for appendix, colon tumors

A patient-specific tumor organoid model is being used to identify the most effective chemotherapy protocol to treat appendix and colon tumors, a personalized medicine approach that is showing promise.

7 Aug 2020

Study: Drinking honeysuckle decoction accelerates the negative conversion of COVID-19 patients

In a new study in Cell Discovery, Chen-Yu Zhang's group at Nanjing University and two other groups from Wuhan Institute of Virology and the Second Hospital of Nanjing present a novel finding that absorbed miRNA MIR2911 in honeysuckle decoction (HD) can directly target SARS-CoV-2 genes and inhibit viral replication. Drinking of HD accelerate the negative conversion of COVID-19 patients.

7 Aug 2020

Electric multicookers could be used for sanitization of N95 respirator masks

Owners of electric multicookers may be able to add another use to its list of functions, a new study suggests: sanitization of N95 respirator masks.

6 Aug 2020

Will smoking cannabis harm your heart?, yes says AMA

The American Heart Association (AHA), in their statement, has said that smoking cannabis (marijuana) could be harmful to the heart. This new stand on smoking weed was published this week in the journal Circulation. The announcement is released as an article titled, “Medical Marijuana, Recreational Cannabis, and Cardiovascular Health: A Scientific Statement From the American Heart Association.”

6 Aug 2020

New alpha-radioimmunotherapy for multiple myeloma shows promise in preclinical study

A new alpha-radioimmunotherapy, 212Pb-anti-CD38, has proven effective in preventing tumor growth and increasing survival in multiple myeloma tumor-bearing mice, according to new research published in the July issue of the Journal of Nuclear Medicine. Given the long half-life, central production and worldwide distribution of 212Pb-anti-CD38, researchers have determined that the α-radioimmunotherapy is not only effective but also clinically feasible as a multiple myeloma treatment.

6 Aug 2020

Non-hormonal therapy found to be effective for menopause-associated symptoms

A non-hormonal therapy to treat hot flashes and other symptoms associated with menopause was found to be effective in a recent clinical trial, according to a published study by a team of researchers including faculty from the University of Colorado School of Medicine.

6 Aug 2020

America’s obesity epidemic threatens effectiveness of any COVID vaccine

For a world crippled by the coronavirus, salvation hinges on a vaccine.

6 Aug 2020

Synthetic peptide can make multidrug-resistant bacteria sensitive to antibiotics

Scientists at Nanyang Technological University, Singapore (NTU Singapore) have developed a synthetic peptide that can make multidrug-resistant bacteria sensitive to antibiotics again when used together with traditional antibiotics, offering hope for the prospect of a combination treatment strategy to tackle certain antibiotic-tolerant infections.

6 Aug 2020

Cytiva licenses advanced machine learning technology from Allen Institute

Cytiva and the Allen Institute have entered into a license agreement to integrate the Allen Institute's machine learning technology with Cytiva's microscopy and image analysis systems to advance the development of cell imaging innovations.

From Cytiva Life Sciences 6 Aug 2020

Researchers shed new light on epigenetic changes associated with ADNP syndrome

A study led by the Seaver Autism Center for Research and Treatment at Mount Sinai found that two different blood epigenetic signatures associated with ADNP syndrome (also known as Helsmoortel-Van Der Aa syndrome) have only a modest correlation with clinical manifestations of the syndrome. The study results were published online August 5 in the American Journal of Human Genetics.

6 Aug 2020

Scientists create new mouse model of permanent neonatal diabetes

Diabetes seldom occurs in newborns--a condition known as neonatal diabetes. But when it does, it's mostly due to a mutation in a single gene such as the KCNJ11 or insulin (INS).

6 Aug 2020

Face masks protect from COVID-19 and other respiratory illnesses

Now a new study published on the preprint server medRxiv in August 2020, therefore, presents the results of a meta-analysis that takes account of the lack of compliance with mask-wearing in RCTs, as well as the lag between the event and the measurable effects.

6 Aug 2020

HDAC6 inhibitors increase efficacy of immunotherapy in triple-negative breast cancer

Genetic modifier HDAC6 was found to control tumor growth and halt metastasis in triple-negative breast cancer in vivo, according to a new study published in the top-tier journal Cancer Research by investigators at the George Washington University (GW) Cancer Center.

6 Aug 2020

New medical imaging resource center at UChicago will help tackle COVID-19 pandemic

A new center hosted at the University of Chicago -- co-led by the largest medical imaging professional organizations in the country -- will help tackle the ongoing COVID-19 pandemic by curating a massive database of medical images to help better understand and treat the disease.

5 Aug 2020

Efficacy News and Research

Nanomedicine-based strategy enhances anti-PD1 therapy to eradicate PTEN-negative GBM

Custom smartwatch tracks drug levels inside the body in real time

How misinformation undermines Australia's COVID-19 response

Researchers use patient-specific tumor organoid to optimize chemotherapy for appendix, colon tumors

Study: Drinking honeysuckle decoction accelerates the negative conversion of COVID-19 patients

Electric multicookers could be used for sanitization of N95 respirator masks

Will smoking cannabis harm your heart?, yes says AMA

New alpha-radioimmunotherapy for multiple myeloma shows promise in preclinical study

Non-hormonal therapy found to be effective for menopause-associated symptoms

America’s obesity epidemic threatens effectiveness of any COVID vaccine

Synthetic peptide can make multidrug-resistant bacteria sensitive to antibiotics

Cytiva licenses advanced machine learning technology from Allen Institute

Researchers shed new light on epigenetic changes associated with ADNP syndrome

Scientists create new mouse model of permanent neonatal diabetes

Face masks protect from COVID-19 and other respiratory illnesses

HDAC6 inhibitors increase efficacy of immunotherapy in triple-negative breast cancer

New medical imaging resource center at UChicago will help tackle COVID-19 pandemic

NIH-Moderna investigational vaccine protects mice from infection with SARS-CoV-2

New serological test for COVID-19 helps determine herd immunity, vaccine efficacy

Bisphosphonates may be safe and beneficial for osteoarthritis patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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