Cortisol is a hormone made by the adrenal cortex (the outer layer of the adrenal gland). It helps the body use glucose (a sugar), protein, and fats. Cortisol made in the laboratory is called hydrocortisone. It is used to treat many conditions, including inflammation, allergies, and some cancers. Cortisol is a type of glucocorticoid hormone.
New Phase III data found that investigational linagliptin therapy resulted in significant reductions in blood sugar as measured by hemoglobin A1c (HbA1c) when compared to placebo, both when added to sulfonylurea (SU) in inadequately controlled type 2 diabetes (T2D) patients, and when administered as monotherapy in T2D patients for whom metformin is inappropriate.
Novartis Pharmaceuticals Corporation announced today that the results of a Phase III study of SOM230 (pasireotide) showed a reduction in cortisol levels in patients with Cushing's disease, a condition in which a benign (non-cancerous) pituitary tumor causes the adrenal glands to produce excess cortisol and can be fatal. Results will be presented at the 14th Congress of the European Neuroendocrine Association (ENEA).
According to a new study, women prefer calm men to stressed ones. Researchers at the University of Abertay Dundee in Scotland found that women were more attracted to calm, collected men with lower levels of the stress hormone cortisol coursing through their systems, than men who are chronically stressed. The study was published in the Proceedings of the Royal Society B journal. The researchers also found that there was no clear association between attractiveness and high levels of testosterone as was thought before.
Heart patients with the "distressed" (Type D) personality profile may face a higher risk of future cardiovascular problems, according to a summary article published in the American Heart Association journal Circulation: Cardiovascular Quality and Outcomes.
High levels of the stress hormone cortisol strongly predict cardiovascular death among both persons with and without pre-existing cardiovascular disease according to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).
Researchers in Cedars-Sinai's Department of Psychiatry and Behavioral Neurosciences have reported people who undergo massage experience measureable changes in their body's immune and endocrine response.
People who sleep less than six hours a night may be three times more likely to develop a condition which leads to diabetes and heart disease, according to researchers at the University of Warwick.
People who sleep less than six hours a night may be three times more likely to develop a condition which leads to diabetes and heart disease, according to researchers at the University of Warwick.
Today, The Endocrine Society released a new clinical practice guideline on the diagnosis and treatment of congenital adrenal hyperplasia (CAH). The guideline features a series of evidence-based clinical recommendations developed by an expert task force.
Researchers at The University of Western Ontario have provided the first direct evidence using a biological marker, to show chronic stress plays an important role in heart attacks.
If your body releases cortisol with fixed regularity then you can cope with stress better, says NWO-funded researcher Angela Sarabdjitsingh. She investigated the rhythm of corticosterone production in rats. This rat hormone is comparable to the human stress hormone cortisol. Rats deal considerably less well with stress if the pattern of corticosterone release changes. An irregular release pattern is a characteristic of chronic stress and stress-related diseases. It might therefore be possible to treat these by restoring the rhythm.
All humans are synchronised to the rhythmic light-dark changes that occur on a daily basis. Rhythms in physiological and biochemical processes and behavioural patterns persist in the absence of all external 24-hour signals from the physical environment, with a period that is close to 24 hours
Being married has often been associated with improving people's health, but a new study suggests that having that long-term bond also alters hormones in a way that reduces stress.
People suffering from diabetes-related foot ulcers show different rates of healing according to the way they cope and their psychological state of mind, according to new research by a health psychologist at The University of Nottingham.
A remote Canadian island is being used to simulate isolated space flight conditions for a NASA-funded medical research study that could produce important information to assist astronauts in potential long duration flights to Mars or an asteroid.
MDMA (-3,4-methylenedioxymethamphetamine, also known as Ecstasy), may one day offer hope for individuals with posttraumatic stress disorder (PTSD), even people for whom other treatments have failed. Clinical trial results out today in the Journal of Psychopharmacology, published by SAGE, suggests that MDMA can be administered to subjects with PTSD without evidence of harm and could offer sufferers a vital window with reduced fear responses where psychotherapy can take effect.
Rebuilding schools after Hurricane Katrina and providing supportive environments and relationships have helped many children reduce their levels of overall trauma from the hurricane that devastated the Gulf Coast in August 2005, according to a new study. A second study found that girls had distinct stress reactions from boys in the aftermath of the storm.
Now, in the first such study in living humans, researchers at UCLA suggest a cause, and it's not psychological, but physical: atrophy of a specific region of the hippocampus, a critical part of the brain involved in mood and memory, among other functions.
Marianne Kraugerud's doctoral research has led to the discovery that individual variants of the environmental pollutants PCB and PFC can affect several of the body's hormone systems in a more complex way than previously supposed. Humans and animals are constantly exposed to these toxins through the food they eat and the air they breathe. Kraugerud concludes that the impact of these pollutants should be taken into account when carrying out risk appraisals of PCB and PFC.
New research shows that a unique strain of laboratory mice characterized at Penn State University has behavioral, hormonal, and neurochemical characteristics that are similar to those of human patients with drug-resistant forms of depression.
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