Hematology News and Research

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Hematology, also spelled haematology, is the branch of biology (physiology), pathology, clinical laboratory, internal medicine, and pediatrics that is concerned with the study of blood, the blood-forming organs, and blood diseases. Hematology includes the study of etiology, diagnosis, treatment, prognosis, and prevention of blood diseases.

A new cell-based gene therapy approach to better treat patients with hemophilia A

In a new study from the Wake Forest Institute for Regenerative Medicine researchers have developed an optimized cellular platform for delivering Factor 8 to better treat patients with hemophilia A.

28 Jul 2020

Study shows how aging causes lung regeneration to go awry

Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have identified the process by which stem cells in the airways of the lungs switch between two distinct phases -- creating more of themselves and producing mature airway cells -- to regenerate lung tissue after an injury.

28 Jul 2020

Study could lead to treatments that prevent deadly metastasis

Tiny finger-like projections called filopodia drive invasive behavior in a rare subset of lung cancer cells, researchers at Winship Cancer Institute of Emory University have found.

28 Jul 2020

Researchers identify anticoagulation agent that suppresses SARS-CoV-2 replication in vitro

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can cause acute respiratory distress syndrome, hypercoagulability, hypertension, and multiorgan dysfunction.

27 Jul 2020

Researcher receives Outstanding Investigator Award for groundbreaking microvascular and circulation research

Sarah Yuan, MD, PhD, professor and chair of the Department of Molecular Pharmacology and Physiology at the USF Health Morsani College of Medicine, has received a highly competitive National Heart, Lung, and Blood Institute (NHLBI) Outstanding Investigator Award to continue breaking new ground in microvascular and circulation research.

25 Jul 2020

Spinal cord injuries in mice cause acquired bone marrow failure syndrome

Research conducted at The Ohio State University Wexner Medical Center and The Ohio State University College of Medicine found that spinal cord injuries in mice cause an acquired bone marrow failure syndrome that may contribute to chronic immune dysfunction.

24 Jul 2020

Neo-self antibody could be a major cause of recurrent pregnancy loss

A research group centered around Kobe University Graduate School of Medicine's Professor YAMADA Hideto and Associate Professor TANIMURA Kenji (Department of Obstetrics and Gynecology), and Professor ARASE Hisashi et al. of Osaka University's Research Institute for Microbial Diseases (RIMD) have revealed for the first time in the world the high frequency of a novel autoantibody in women suffering from recurrent pregnancy loss.

23 Jul 2020

Research could lead to more efficient cellular immunotherapies for advanced cancers

Adoptive cell transfer immunotherapy is one of the most promising new treatments for people with hard-to-treat cancers.

23 Jul 2020

GlobalData: Hematology tests can be a prognostic marker to predict severity of COVID-19 patients

With the rapid increase in the number of COVID-19 cases across India, identifying the critically ill COVID-19 patients in the early stage of infection can help in assessing the risk stratification and clinical management.

21 Jul 2020

A comprehensive review of COVID-19's effect on organ systems outside the lungs

In the early days of the COVID-19 pandemic, the disease was characterized by many as a flu-like respiratory infection mainly affecting the lungs.

20 Jul 2020

Immunotherapy does not worsen complications for patients with both COVID-19 and cancer

Preliminary data from researchers at the University of Cincinnati Cancer Center show that immunotherapy doesn't necessarily worsen complications for patients with both COVID-19 and cancer.

20 Jul 2020

Josep Carreras Institute's spin-off aims to develop new immuno-oncological therapeutic tools

The Josep Carreras Leukaemia Research Institute, a public centre pertaining to the Generalitat de Catalunya's (Government of Catalonia) CERCA network, has created the OneChain Immunotherapeutics spin-off, the aim of which is to develop new immuno-oncological therapeutic tools with various preclinical candidates, based on CAR-T technology for different tumors, such as cortical T-cell acute lymphoblastic leukemia (coT-ALL), a rare subtype of leukemia that mainly affects children, and which has a poor prognosis.

20 Jul 2020

Rare inherited mutation in TP53 gene confers risk of multiple cancers

Rare inherited mutations in the body's master regulator of the DNA repair system – the TP53 gene – can leave people at a higher risk of developing multiple types of cancer over the course of their lives.

16 Jul 2020

Likelihood of SARS-CoV-2 transmission may depend on blood type of spreader and recipient

A modeling study by Dr. Peter Ellis from the University of Kent indicates that ABO incompatibility between infected patients and susceptible individuals may actually decrease the transmissibility of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by 60% or more. His detailed investigation of such "ABO-interference" can be found on the medRxiv preprint server.

15 Jul 2020

Promising new CAR T cell therapy results in exceptional patient recovery

In a clinical trial evaluating a novel immunotherapy option for cancer treatment, a child with rhabdomyosarcoma, a form of muscle cancer, that had spread to the bone marrow, showed no detectable cancer following treatment with chimeric antigen receptor (CAR) T cells that were engineered to target the HER2 protein on the surface of the cancer cells.

15 Jul 2020

Dual inhibitor therapy may be safer for CLL patients, Moffitt study shows

Chronic lymphocytic leukemia (CLL) is the most common leukemia in adults. One in four new leukemia cases are CLL.

14 Jul 2020

Clots, COVID-19 and survival

The novel coronavirus, now known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), that causes COVID-19 disease, was first reported in Wuhan, Hubei Province of China in late December 2019. Since then, it has infected a large population across the world with the current number of SARS-CoV-2 infections standing at over 13 million and COVID-19 disease having killed over 571,000 individuals.

13 Jul 2020

Researchers develop new approach to assess changes in tumor microenvironment

Research has shown that the tumor microenvironment (TME) can help cancers grow and evade the immune response. The TME has even been shown to inhibit cellular immunotherapy, a novel form of treatment in which the cells of a patient's immune system are re-engineered in the lab to attack cancer cells.

12 Jul 2020

First extensive review of COVID-19's effects on all affected organs outside the lungs

After only a few days caring for critically ill COVID-19 patients at the start of the outbreak in New York City, Aakriti Gupta, MD, realized that this was much more than a respiratory disease.

12 Jul 2020

Newly identified gene variants in Black Americans could lead to precision prostate cancer therapies

Black men in the United States are known to suffer disproportionately from prostate cancer, but few studies have investigated whether genetic differences in prostate tumors could have anything to do with these health disparities.

11 Jul 2020

Hematology News and Research

Further Reading

A new cell-based gene therapy approach to better treat patients with hemophilia A

Study shows how aging causes lung regeneration to go awry

Study could lead to treatments that prevent deadly metastasis

Researchers identify anticoagulation agent that suppresses SARS-CoV-2 replication in vitro

Researcher receives Outstanding Investigator Award for groundbreaking microvascular and circulation research

Spinal cord injuries in mice cause acquired bone marrow failure syndrome

Neo-self antibody could be a major cause of recurrent pregnancy loss

Research could lead to more efficient cellular immunotherapies for advanced cancers

GlobalData: Hematology tests can be a prognostic marker to predict severity of COVID-19 patients

A comprehensive review of COVID-19's effect on organ systems outside the lungs

Immunotherapy does not worsen complications for patients with both COVID-19 and cancer

Josep Carreras Institute's spin-off aims to develop new immuno-oncological therapeutic tools

Rare inherited mutation in TP53 gene confers risk of multiple cancers

Likelihood of SARS-CoV-2 transmission may depend on blood type of spreader and recipient

Promising new CAR T cell therapy results in exceptional patient recovery

Dual inhibitor therapy may be safer for CLL patients, Moffitt study shows

Clots, COVID-19 and survival

Researchers develop new approach to assess changes in tumor microenvironment

First extensive review of COVID-19's effects on all affected organs outside the lungs

Newly identified gene variants in Black Americans could lead to precision prostate cancer therapies

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

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