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Exploring SARS-CoV-2 spike evolution in relation to sensitivity to antiviral restriction factors

Researchers investigated the effects of SARS-CoV-2 spike mutations on antiviral restriction mediated by interferon-induced transmembrane proteins and guanylate binding proteins.

11 Mar 2022

LMU scientists find specific immunological signature that can prevent SARS-CoV-2 virus spread

LMU scientists have investigated how most people's immune defenses are able to curb the coronavirus so effectively that pneumonia does not occur.

10 Mar 2022

CRIPSR identifies cell-type-specific ACE2 modifiers

Researchers compile a list of candidate genes to identify the surface abundance of functional regulators of ACE2.

9 Mar 2022

Lower exosome component 2 expression protects against clinical SARS-CoV-2 infection

In a recent study posted to the bioRxiv* preprint server, researchers demonstrated that the lower expression of EXOSC2 human protein safeguards from clinical coronavirus disease 2019 (COVID-19). This protective effect was via the reduced EXOSC2 expression-associated suppression of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication.

9 Mar 2022

Whole-genome sequencing for determination of factors associated with critical COVID-19

In a recent study published in the journal Nature as an early release unedited manuscript, researchers conducted whole genomic sequencing (WGS) to ascertain factors contributing to critical coronavirus disease 2019 (COVID-19).

8 Mar 2022

A promising approach for COVID-19 prophylaxis

SARS-CoV-2 viruses can hide from recognition by the immune system. However, the antiviral immune receptor RIG-I can be stimulated, which improves protection against lethal SARS-CoV-2 infections.

8 Mar 2022

Comparative immunogenicity of reduced and standard BNT162b2 and mRNA-1273 boosters in CoronaVac vaccinees

Researchers compared the immunogenicity of the reduced and standard doses of the BNT162b2 and mRNA-1273 vaccine in adults immunized with two doses of the CoronaVac vaccine.

8 Mar 2022

World's largest genetic study reveals fresh details about severe Covid-19

The world's largest study of the genetics of critical Covid-19, involving more than 57,000 people, has revealed fresh details about some of the biological mechanisms behind the severe form of the disease.

7 Mar 2022

Study explores differentially expressed immune genes for COVID-19 patient stratification

In a new study, researchers determined the transcriptional signatures associated with the severity of COVID-19.

7 Mar 2022

Current progress in SARS-CoV-2 vaccine candidates

In a new study, researchers illustrated the current progress and obstacles in COVID-19 vaccine development.

7 Mar 2022

Combating COVID cytokine storm with targeted nucleic acid therapies

Researchers examine current nucleic acid-based treatments against COVID-19 and their methods of action.

6 Mar 2022

CD4 T-cell immunity active six months into COVID-19 convalescence

A new paper explores the presence of CD4 T-cell-mediated adaptive immunity against SARS-CoV-2 in late convalescence.

6 Mar 2022

Disruption of sleep and circadian rhythm can increase the chances of contracting a virus

A recent study explores the effect of sleep and circadian rhythm dispersion on mouse lung transcriptome after six of hours sleep deprivation.

6 Mar 2022

Third dose of COVID mRNA vaccine safe and effective in kidney transplant patients

An new study reports that a third dose of the Pfizer BNT162b2 vaccine produces high levels of anti-spike IgG antibodies in kidney transplant recipients.

6 Mar 2022

Omicron-specific mRNA vaccine generates immune responses in mice, hamsters and Macaques

Researchers develop an Omicron variant mRNA vaccine that is be more potent in generating nAbs as compared to other available vaccines.

6 Mar 2022

T-cell cytokine and fatty acid work together to trigger a type of cell death

Researchers at the University of Michigan Rogel Cancer Center found that a cytokine, a category of protein that acts as messengers in the body, and a fatty acid can work together to trigger a type of cell death previously defined by studies with synthetic molecules.

4 Mar 2022

Interferon News and Research

Exploring SARS-CoV-2 spike evolution in relation to sensitivity to antiviral restriction factors

LMU scientists find specific immunological signature that can prevent SARS-CoV-2 virus spread

CRIPSR identifies cell-type-specific ACE2 modifiers

Lower exosome component 2 expression protects against clinical SARS-CoV-2 infection

Whole-genome sequencing for determination of factors associated with critical COVID-19

A promising approach for COVID-19 prophylaxis

Comparative immunogenicity of reduced and standard BNT162b2 and mRNA-1273 boosters in CoronaVac vaccinees

World's largest genetic study reveals fresh details about severe Covid-19

Study explores differentially expressed immune genes for COVID-19 patient stratification

Current progress in SARS-CoV-2 vaccine candidates

Combating COVID cytokine storm with targeted nucleic acid therapies

CD4 T-cell immunity active six months into COVID-19 convalescence

Disruption of sleep and circadian rhythm can increase the chances of contracting a virus

Third dose of COVID mRNA vaccine safe and effective in kidney transplant patients

Omicron-specific mRNA vaccine generates immune responses in mice, hamsters and Macaques

T-cell cytokine and fatty acid work together to trigger a type of cell death

Multigranular and visualization approach precisely predicts SARS-CoV-2 outcomes

Assessing the potential of IFNa subtypes in suppressing SARS-CoV-2

Scientists find no connection between pandemic chilblains and SARS-CoV-2 infection

Adenosine receptor agonists provide therapeutic target in mouse SARS-CoV-2 infection

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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