Kidney News and Research

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Can one drug do it all? Reviewing the expanding clinical universe of GLP-1 agonists

Landmark trials have shown that GLP-1 receptor agonists, originally developed for diabetes and weight loss, also provide significant benefits for cardiovascular, kidney, liver, joint, and sleep-related diseases. These effects extend beyond weight loss, suggesting anti-inflammatory mechanisms with broad potential for managing chronic diseases.

22 Jul 2025

Mapping metformin’s kidney effects through spatial multi-omics

Metformin is a widely used first-line therapy for type 2 diabetes, and studies increasingly point to its protective effects on the kidney.

22 Jul 2025

New imaging technique reveals how cells organize glucose processing

In a scientific first, researchers from Vanderbilt University and the University of California, San Diego, have generated a high-resolution metabolic "map" of how cells orchestrate glucose processing, revealing a hidden world where organelles and molecular complexes collaborate when responding to a rush of nutrients.

22 Jul 2025

Mount Sinai researcher uncovers how the brain and body interact in aging and depression

In a comprehensive Genomic Press interview published in Brain Medicine today, Dr. Hamilton Se-Hwee Oh reveals groundbreaking insights into the complex dialogue between our brains and bodies that fundamentally shapes aging, depression, and neurodegenerative disease.

22 Jul 2025

Amid PFAS fallout, a Maine doctor navigates medical risks with her patients

When Lawrence and Penny Higgins of Fairfield, Maine, first learned in 2020 that high levels of toxic chemicals called PFAS taint their home's well water, they wondered how their health might suffer.

22 Jul 2025

Uranium isotope in urine identified as early warning sign of kidney damage

A new study by researchers at Columbia University Mailman School of Public Health identified that uranium's isotopic composition can be used as a biomarker to noninvasively measure accumulation of uranium in the kidneys.

22 Jul 2025

Muscle-derived vesicles heal damaged cells and reverse disease in new study

Researchers discovered that mitochondria-rich extracellular vesicles (Ti-mitoEVs) from skeletal muscle can deliver healthy mitochondria to damaged cells, restoring energy and promoting tissue repair in mice. The approach reversed acute muscle injury and chronic kidney disease, offering a promising new regenerative therapy.

21 Jul 2025

Hypertensive disorders in pregnancy linked to lower breastfeeding rates

Hypertensive disorders in pregnancy (HDP) - like chronic or gestational hypertension, preeclampsia, and eclampsia - are among the leading causes of maternal and infant death in the United States.

18 Jul 2025

Heart-healthy habits can improve overall physical and psychological well-being

A new study from Emory University reveals that maintaining optimal cardiovascular health can significantly improve overall physical and psychological well-being.

18 Jul 2025

Microbial therapy uses modified bacteria to target oxalate in the gut

Engineered gut bacteria designed to treat kidney stones successfully colonized the gut microbiome and reduced oxalate levels in animal models and early clinical trials in humans, researchers report.

18 Jul 2025

Study identifies SDR42E1's role in vitamin D pathway

Vitamin D is not only an essential nutrient, but also the precursor of the hormone calcitriol, indispensable for health: it regulates the uptake of phosphate and calcium necessary for bones by the intestines, as well as cell growth and the proper function of muscles, nerve cells, and the immune system.

18 Jul 2025

Polyglycine aggregates disrupt tRNA splicing and drive neurodegeneration

Neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease, are devastating and incurable diseases.

17 Jul 2025

Uncovering a protective RNA molecule in kidney stress and disease

Cells contain helper molecules called transfer RNAs (tRNAs), which carry building blocks (amino acids) to make proteins.

17 Jul 2025

Study reveals how aging alters liver function and structure

The aging liver undergoes dramatic changes in its functional organization and other key attributes, which may underpin its increasing susceptibility to disease, according to a study led by investigators at Weill Cornell Medicine.

17 Jul 2025

Maybe it’s not just aging. Maybe it’s anemia.

Gary Sergott felt weary all the time. "I'd get tired, short of breath, a sort of malaise," he said. He was cold even on warm days and looked pale with dark circles under his eyes.

17 Jul 2025

New genetic marker improves kidney transplant match predictions

Researchers at the University of Pittsburgh have identified a new way of predicting whether a kidney donor and recipient are a good match for transplantation.

17 Jul 2025

Heart healthy habits boost overall body health and longevity

People who had more heart-healthy habits and factors, as assessed by the American Heart Association's Life's Simple 7 metrics for ideal cardiovascular health, had more positive benefits for whole body health, according to a review of research published today in the Journal of the American Heart Association, an open-access, peer-reviewed journal of the American Heart Association.

16 Jul 2025

Research unravels the immune secrets of a cured pediatric rhabdoid tumor

Although relatively rare, many childhood cancers remain life-threatening and lack effective personalized treatments. Rhabdoid tumors are among these fatal cancers and can develop in various tissues and organs.

16 Jul 2025

Childhood heart health predicts lifelong well-being, study finds

Optimal heart health from birth through adolescence, as measured by a combination of metrics, leads to long-lasting cardiovascular and overall physical, cognitive and mental health, according to the systematic review published in the Journal of the American Heart Association.

16 Jul 2025

AI tool predicts tumor aggressiveness using protein markers

As cancer cases have increased worldwide, the disease has become more complex, presenting challenges to scientific advances in diagnosis and treatment.

15 Jul 2025