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Engineered virus-like particles evolve for superior gene delivery efficiency

Researchers developed a barcoded directed evolution system for engineered virus-like particles (eVLPs), creating a fifth-generation (v5) eVLP with enhanced production, transduction, and gene-editing efficiency. This system could pave the way for improved gene delivery vehicles in therapeutic applications.

17 Nov 2024

Study reveals skin tone bias in photoacoustic imaging for breast cancer detection

Breast cancer is a major health concern worldwide, and early detection is crucial for effective treatment. Traditional imaging methods, such as mammography, have limitations, especially for women with dense breast tissue.

15 Nov 2024

New drug strategy reverses resistance to immunotherapy in pancreatic cancer

A new drug strategy that regulates the tumor immune microenvironment may transform a tumor that resists immunotherapy into a susceptible one, according to a study by researchers from the Johns Hopkins Kimmel Cancer Center and Oregon Health & Science University.

14 Nov 2024

MaxCyte celebrates 25 years of innovation driving cell engineering-based therapeutics

MaxCyte, Inc., a leading, cell-engineering focused company providing enabling platform technologies to advance the discovery, development and commercialization of next-generation cell therapeutics, marks the 25th anniversary of its founding this year.

From MaxCyte, Inc. 13 Nov 2024

CAR T cell therapy breakthroughs bring new hope for treating solid tumors

Researchers advance CAR T cell therapy for solid tumors by innovating ways to overcome the unique barriers of solid tumor environments, with promising clinical results.

13 Nov 2024

Metagenomic sequencing improves detection of rare pathogens in CNS infections

New research shows that metagenomic next-generation sequencing (mNGS) over seven years increased pathogen detection in challenging CNS infections, identifying rare and unexpected microbes often missed by standard testing.

13 Nov 2024

Scientists discover new breakthrough in weight loss and diabetes treatment

Scientists at the University of Copenhagen have discovered a new weight loss drug target that reduces appetite, increases energy expenditure, and improves insulin sensitivity without causing nausea or loss of muscle mass.

13 Nov 2024

Utilizing process Raman in optimizing cultivated meat production

Learn about the usage of process raman spectroscopy in the optimization of bioreactor monitoring and then improvement of cultivated meat production.

From Thermo Fisher Scientific – Pharmaceutical and Biopharmaceutical Solutions 13 Nov 2024

Next-generation metagenomic sequencing test quickly detects any kind of pathogen

Next-generation metagenomic sequencing test developed at UCSF proves its effectiveness in quickly diagnosing almost any kind of pathogen.

12 Nov 2024

AI tool tracks infant movement to predict neurologic changes in NICU

A team of clinicians, scientists, and engineers at Mount Sinai trained a deep learning pose-recognition algorithm on video feeds of infants in the neonatal intensive care unit (NICU) to accurately track their movements and identify key neurologic metrics.

11 Nov 2024

Studies link gut dysbiosis to pancreatic cancer, offering pathways for early detection

The gut microbiome's impact on pancreatic cancer highlights potential for early screening and fecal microbiota transplantation in improving treatment efficacy.

11 Nov 2024

MD Anderson launches new institute for advancing cell therapy

The University of Texas MD Anderson Cancer Center today announced the launch of its Institute for Cell Therapy Discovery & Innovation, which will build upon longstanding MD Anderson clinical and research expertise to lead the world in developing and advancing impactful cell therapies for patients in need.

8 Nov 2024

Survey reveals alarming dental decay rates in Kentucky preschoolers

The University of Kentucky College of Dentistry's 2023 Kentucky Early Learners' Oral Health Surveillance Project survey found dental decay rates for Kentucky children ages 2 through 5 are significantly higher than the national average.

7 Nov 2024

Assessing recurrence risk with ctDNA-based MRD detection in NSCLC patients

In operable non-small cell lung cancer (NSCLC), molecular residual disease (MRD) detection via circulating tumor DNA (ctDNA) has emerged as a promising approach to identify individuals at high risk of disease recurrence and potentially guide adjuvant therapy decisions.

6 Nov 2024

Mount Sinai researchers uncover key process in memory integration

Mount Sinai researchers have discovered for the first time a neural mechanism for memory integration that stretches across both time and personal experience.

6 Nov 2024

Advances in neutropenia research could pave the way for better treatments

Neutropenia is a condition in which there are not enough neutrophils, a type of white blood cell, in the blood.

5 Nov 2024

AI-powered ECG model predicts heart disease risk with precision

A new AI-enhanced ECG model, AIRE, accurately predicts mortality and heart disease risk, providing clinicians with actionable, patient-specific insights.

5 Nov 2024

SpaceX CRS-31 supports heart health, neurodegeneration, and student science

More than 25 payloads sponsored by the International Space Station (ISSInternational Space Station) National Laboratory, including technology demonstrations, in-space manufacturing, student experiments, and multiple projects funded by the U.S. National Science Foundation (NSF), are bound for the orbiting outpost.

4 Nov 2024

Researchers achieve accurate EV analysis to detect brain disease

Brain disorders like Parkinson's (PD) or Alzheimer's Disease (AD) start to develop in patients much earlier than when their first clinical symptoms appear. Treating patients at these early stages could slow or even stop their disease, but there is currently no way to diagnose brain disorders at those pre-symptomatic stages.

3 Nov 2024

Enhanced screening protocols for Candida auris improve hospital infection control

Mount Sinai researchers have enhanced hospital screening protocols for Candida auris, an often-drug-resistant fungal pathogen the Centers for Disease Control and Prevention considers an urgent global health threat.

1 Nov 2024