Statin News and Research

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Statins are drugs used to lower cholesterol. Your body needs some cholesterol to work properly. But if you have too much in your blood, it can stick to the walls of your arteries, narrowing or even blocking them.

Omthera initiates ECLIPSE study for treatment of high triglycerides

Omthera Pharmaceuticals, Inc., a privately-held emerging specialty pharmaceuticals company, today announced the initiation of a randomized, open-label, four-way cross-over pharmacokinetics study to evaluate the bioavailability of Epanova, Omthera's lead compound for the treatment of very high triglycerides, in comparison to Lovaza, the leading prescription Omega-3.

9 Nov 2010

Positive results from Ardea's RDEA594 combination study with febuxostat or allopurinol for gout

Ardea Biosciences, Inc. announced positive results from two clinical studies of RDEA594 in combination with currently marketed drugs for the treatment of gout patients, febuxostat (Uloric®) and allopurinol.

8 Nov 2010

Statin drugs do not benefit pediatric lupus patients

Lupus puts children at higher risk for coronary artery disease when they become adults, but routinely using statins doesn't provide enough benefit to warrant their regular use in children and adolescents, according to the largest study of pediatric lupus patients to date.

8 Nov 2010

Research Roundup: Basing insurance on results, not cost; Americans skeptical of public health efforts; seniors' comprehensive care

Copayment Reductions Generate Greater Medication Adherence In Targeted Patients. As health care costs have increased, some patients have sought to save money by cutting down on their medications.

8 Nov 2010

Eliminating copayments for high-value prescription drugs improves employees' adherence to treatment regimens

An initiative by the U. S. technology company Pitney Bowes to make medications of proven value less expensive for their employees succeeded in stabilizing employees' adherence to their treatment regimens, according to a Commonwealth Fund-supported study published in this month's Health Affairs.

3 Nov 2010

Essentialis, FDA enter agreement on SPA for DCCR Phase 3 efficacy study in patients with high triglycerides

Essentialis, Inc. announced today that the company has reached agreement with the U.S. Food and Drug Administration (FDA) on a Special Protocol Assessment (SPA) for a Phase 3 efficacy study required for product registration for its product candidate, Diazoxide Choline Controlled Release Tablet (DCCR), for the treatment of patients with very high triglycerides.

25 Oct 2010

New guidelines feature various key updates for stroke or TIA survivors

Treating metabolic syndrome and undergoing carotid angioplasty may prevent recurrent stroke or transient ischemic attack, according to revised American Heart Association/American Stroke Association guidelines.

22 Oct 2010

Abbott third quarter worldwide sales increase 11.8% to $8.7 billion

Abbott today announced financial results for the third quarter ended Sept. 30, 2010.

20 Oct 2010

Preoperative statin therapy prior to coronary bypass surgery improves survival rate

Findings from a study presented at this year's American Society of Anesthesiologists Annual Meeting reveal that patients who undergo preoperative statin therapy prior to coronary bypass surgery have a better survival rate.

20 Oct 2010

ACG 75th Scientific Meeting to review advances in gastrointestinal research, treatment of digestive diseases

Many of the world's preeminent gastroenterologists will gather for the American College of Gastroenterology's (ACG) 75th Annual Scientific Meeting at the Henry B. Gonzalez Convention Center in San Antonio, Texas starting Monday October 18, 2010, to review the latest scientific advances in gastrointestinal research, treatment of digestive diseases and clinical practice management.

19 Oct 2010

Long-term use of statins reduces colorectal cancer risk

A systematic review of the medical literature supports the hypothesis that statins, cholesterol-lowering drugs used to prevent cardiac problems, are associated with reduced risk of colon and rectal cancers.

19 Oct 2010

Statins reduce risk of colon and rectal cancers: Study

A systematic review of the medical literature supports the hypothesis that statins, cholesterol‐lowering drugs used to prevent cardiac problems, are associated with reduced risk of colon and rectal cancers. A comprehensive analysis by investigators at the University of Michigan at Ann Arbor, included 22 scientific studies with more than 2.5 million combined participants.

18 Oct 2010

Researchers investigate statin drugs to treat lung disease

Researchers at Queen's University Belfast are investigating a potential new treatment for lung disease that could save many lives each year. The research team is studying how statins, drugs which are commonly used to treat high cholesterol, can be used to treat lung disease.

13 Oct 2010

Smoking ban contributes to fewer heart attack deaths: Study

A new study finds that the number of deadly heart attacks in Massachusetts fell by more than 7 percent after the state outlawed smoking in workplaces, a possible sign that the ban contributed to better health as fewer people found themselves around smoke.

8 Oct 2010

Study finds no association between gene variant and risk of coronary disease

A genetic marker touted as a predictor of coronary artery disease is no such thing, according to a study led by researchers at the Stanford University School of Medicine.

7 Oct 2010

Study finds broader statin use as a cost-effective way to prevent heart attack and stroke

A new analysis suggests that broader statin use among adult patients may be a cost-effective way to prevent heart attack and stroke. The Stanford University School of Medicine study also found that using a popular test - a screening for high sensitivity C-reactive protein, or CRP - to identify patients who may benefit from statin therapy would be cost-effective, but only under certain scenarios.

29 Sep 2010

CRP levels vary between ethnically-diverse populations: Study

C-reactive protein (CRP) levels vary between ethnically-diverse populations, and are only partly due to known differences in heart risk among these groups.A single risk level of CRP at 2 mg/L may over or under estimate the need for statin medication in different ethnic groups, especially if other risk factors are not considered.

29 Sep 2010

Researchers investigate performance levels of resident and staff physicians

Research on the quality of US resident physician performance levels has often been limited by lack of a comparison group or strict focus on specific diseases and geographical areas. In order to gain insight on differences in quality of care provided by resident physicians versus staff physicians, Boston Medical Center and Palo Alto Medical Foundation researchers investigated performance of physicians in 33,900 hospital-based outpatient visits throughout the US.

22 Sep 2010

Celera receives patent on KIF6 gene variant

Celera Corporation today announced that the United States Patent and Trademark Office has issued United States Patent 7,799,530 relating to methods of determining heart attack risk by detecting the KIF6 gene variant and reduction of such increased risk by statin therapy.

21 Sep 2010

Crestor suppressed human cancer cells transplanted to mice

A drug commonly prescribed for people with high cholesterol may also be effective in treating prostate cancer, according to new research by Dr. Xiao-Yan Wen at St. Michael's Hospital.

20 Sep 2010

Statin News and Research

Further Reading

Omthera initiates ECLIPSE study for treatment of high triglycerides

Positive results from Ardea's RDEA594 combination study with febuxostat or allopurinol for gout

Statin drugs do not benefit pediatric lupus patients

Research Roundup: Basing insurance on results, not cost; Americans skeptical of public health efforts; seniors' comprehensive care

Eliminating copayments for high-value prescription drugs improves employees' adherence to treatment regimens

Essentialis, FDA enter agreement on SPA for DCCR Phase 3 efficacy study in patients with high triglycerides

New guidelines feature various key updates for stroke or TIA survivors

Abbott third quarter worldwide sales increase 11.8% to $8.7 billion

Preoperative statin therapy prior to coronary bypass surgery improves survival rate

ACG 75th Scientific Meeting to review advances in gastrointestinal research, treatment of digestive diseases

Long-term use of statins reduces colorectal cancer risk

Statins reduce risk of colon and rectal cancers: Study

Researchers investigate statin drugs to treat lung disease

Smoking ban contributes to fewer heart attack deaths: Study

Study finds no association between gene variant and risk of coronary disease

Study finds broader statin use as a cost-effective way to prevent heart attack and stroke

CRP levels vary between ethnically-diverse populations: Study

Researchers investigate performance levels of resident and staff physicians

Celera receives patent on KIF6 gene variant

Crestor suppressed human cancer cells transplanted to mice

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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