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Twenty-five million Americans suffer from ulcers. An ulcer is a sore or hole in the lining of the stomach or duodenum (the first part of the small intestine). People of any age can get an ulcer and women are affected just as often as men.

Helicobacter pylori (H. pylori) is a bacterium that lives on the lining of the stomach. Although we used to think that spicy food, acid, and stress were the major causes of ulcers, we now know that nine out of ten ulcers are caused by H. pylori. Medicines that reduce stomach acid may make you feel better, but your ulcer may come back. Here's the good news: Since most ulcers are caused by this bacterial infection, they can be cured with the right antibiotics.

Ibuprofen and naproxen combined with aspirin increase risk of gastrointestinal complications

Patients who combine the common over-the counter pain medications ibuprofen and naproxen with aspirin have a risk of gastrointestinal complications including ulcers, perforations and bleeding that is two to three times greater than patients who take these medications but do not combine them with aspirin.

1 Nov 2005

Regular use of ibuprofen may increase gastrointestinal bleeding

People who take high doses of ibuprofen on a regular basis are three times more likely to experience gastrointestinal (GI) bleeding than those who do not take painkillers.

1 Nov 2005

Possible links between biting aquatic insects, water quality and Buruli ulcer transmission

A tropical skin disease nicknamed "the sore that heals in vain" wreaks both physical and social mayhem - mostly on children - yet its transmission is a mystery, one an Michigan State University (MSU) researcher and his recent research associate hope to solve.

12 Oct 2005

Mayo Clinic researchers find earliest sign of nerve change due to diabetes

Mayo Clinic researchers have found that subtle change in nerve conduction is the first reliable sign of nerve complications from diabetes and that this change can be measured long before other symptoms or signs of nerve damage develop.

3 Oct 2005

Researchers set out to determine the effectiveness of endomorphin 1, with a painkilling capacity equal to or greater than morphine

Nearly one third of the world's adult population suffers with the pain of arthritis. While NSAIDs and COX-2 inhibitors offer the promise of relief, these drugs also bring the risk of adverse effects, from stomach ulcers to heart attack.

3 Oct 2005

100 year old technology to fight MRSA

A technique that has been around for more than one hundred years is being used in new research as a way of killing methicillin-resistant Staphylococcus aureus (MRSA) using light. The research to be reported today at the British Pharmaceutical Conference in Manchester, is being undertaken by researchers from Queen's University Belfast.

28 Sep 2005

Salicylate an active metabolite of aspirin - weakens lipid membranes

It's well known that high doses of aspirin can cause ulcers and temporary deafness, but the biochemical mechanism responsible for these phenomena has never been deciphered.

19 Sep 2005

Cost-cutting strategy employed by HMOs for 15 years is simply not working

With rising concern over the cost of the new Medicare prescription drug benefit program – going into effect January, 2006 and estimated to cost $593 billion over the next decade – a new UCSF study reveals that a key cost-cutting strategy employed by HMOs for 15 years is simply not working.

19 Sep 2005

Human tissue grown from stem cells, available for transplant in the next four years

A team of researchers from the University of Liverpool in the UK have embarked on an ambitious project which could see human tissue grown from stem cells, available for transplant in the next four years.

5 Sep 2005

Dental problems caused by radiation, chemotherapy should be treated before a child undergoes immunosuppression as part of bone marrow transplantation therapy

Many children who undergo bone marrow transplantation (BMT) as part of cancer treatment already have dental abnormalities that leave them vulnerable to potentially life-threatening bacterial infections, according to investigators at St. Jude Children's Research Hospital. A report on this study appears in the prepublication online edition of Bone Marrow Transplantation.

29 Aug 2005

The role of antigenic drive and tumor-infiltrating accessory cells in the pathogenesis of Helicobacter-induced MALT lymphoma

Research led by Dr. Anne Mueller at Stanford University School of Medicine demonstrates that successful eradication of Helicobacter may not prevent future aggressive gastric lymphoma since resting B cells are left behind.

25 Aug 2005

How some antibiotics kill bacteria

Researchers have uncovered how members of one family of antibiotics kill bacteria that make people sick.

11 Aug 2005

Australian lambskin pressure care products granted FDA approval in the U.S.

Export opportunities into the lucrative American market have been thrown wide open for a unique South Australian range of medical lambskin products.

11 Aug 2005

First evaluation of California's much-watched ratios law

There has been much controversy regarding implementation of legislation to regulate hospital nurse-patient staffing ratios and its impact on patient safety and quality outcomes.

9 Aug 2005

Loyola researchers hope that zoledronic acid will be effective and safe for patients with inflammatory bowel diseases (IBD)

Researchers at the Osteoporosis and Metabolic Bone Disease Center and the Division of Gastroenterology at Loyola University Health System are studying a once-yearly, 15-minute infusion of an intravenous (IV) medication in patients with osteopenia (low bone mass) and inflammatory bowel diseases (IBD) that, if proven effective, may be considered the standard of treatment.

26 Jul 2005

New way to fight antibiotic-resistant Staphylococcus infections

Researchers at the University of California, San Diego School of Medicine and Children’s Hospital and Health Center, San Diego have discovered that "Staph" bacteria use a protective golden armor to ward off the immune system, a finding with the potential to lead to new treatments for serious infections now increasingly resistant to standard antibiotics.

19 Jul 2005

Ulcer News and Research

Ibuprofen and naproxen combined with aspirin increase risk of gastrointestinal complications

Regular use of ibuprofen may increase gastrointestinal bleeding

Possible links between biting aquatic insects, water quality and Buruli ulcer transmission

Mayo Clinic researchers find earliest sign of nerve change due to diabetes

Researchers set out to determine the effectiveness of endomorphin 1, with a painkilling capacity equal to or greater than morphine

100 year old technology to fight MRSA

Salicylate an active metabolite of aspirin - weakens lipid membranes

Cost-cutting strategy employed by HMOs for 15 years is simply not working

Human tissue grown from stem cells, available for transplant in the next four years

Dental problems caused by radiation, chemotherapy should be treated before a child undergoes immunosuppression as part of bone marrow transplantation therapy

The role of antigenic drive and tumor-infiltrating accessory cells in the pathogenesis of Helicobacter-induced MALT lymphoma

How some antibiotics kill bacteria

Australian lambskin pressure care products granted FDA approval in the U.S.

First evaluation of California's much-watched ratios law

Loyola researchers hope that zoledronic acid will be effective and safe for patients with inflammatory bowel diseases (IBD)

New way to fight antibiotic-resistant Staphylococcus infections

Australian product promotes healing in venous stasis ulcers

Giving oxygen may do more harm than good

Study sheds new light on the molecular mechanisms underlying the development of chronic wounds

New antibiotic approved by FDA will fight bacterial infections in hospitals

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