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FDA approves first drug to treat children and adults with spinal muscular atrophy

The U.S. Food and Drug Administration today approved Spinraza (nusinersen), the first drug approved to treat children and adults with spinal muscular atrophy (SMA), a rare and often fatal genetic disease affecting muscle strength and movement.

23 Dec 2016

UCLA-led research finds promising results for more personalized head and neck cancer treatment

Researchers have found that people with advanced head and neck squamous cell carcinoma and the KRAS-variant inherited genetic mutation have significantly improved survival when given a short course of the drug cetuximab in combination with standard chemotherapy and radiation.

23 Dec 2016

New Philips HealWell lighting system supports sleep, improves patient experience in healthcare facilities

Philips Lighting, a global leader in lighting, today announced its third generation Philips HealWell lighting system that is specifically developed to support sleep and improve patients’ and staff’s experience, comfort and satisfaction in healthcare facilities.

23 Dec 2016

New computational tool can predict personal cancer driver genes to optimize treatment

Columbia University Medical Center researchers have created a computational tool that can rapidly predict which genes are implicated in an individual's cancer and recommend treatments.

22 Dec 2016

Generative AAE can be radically new way to discover drugs on demand

Scientists at the Pharmaceutical Artificial Intelligence group of Insilico Medicine, Inc, today announced the publication of a seminal paper demonstrating the application of generative adversarial autoencoders (AAEs) to generating new molecular fingerprints on demand.

22 Dec 2016

Heart attack risk for people with HIV nearly 50% higher than predicted

Current methods to predict the risk of heart attack and stroke vastly underestimate the risk in individuals with HIV, which is nearly double that of the general population, reports a new Northwestern Medicine study.

21 Dec 2016

Researchers engineer promising live-attenuated RSV vaccine candidate

Crafting a vaccine against RSV (respiratory syncytial virus) has been a minefield for 50 years, but scientists believe they have found the right balance.

21 Dec 2016

Clinical study tests adult stem cell therapy for infants with congenital HLHS

In a first-in-children randomized clinical study, medical researchers at the University of Maryland School of Medicine and the Interdisciplinary Stem Cell Institute at the University of Miami Miller School of Medicine have begun testing to see whether adult stem cells derived from bone marrow benefit children with the congenital heart defect hypoplastic left heart syndrome (HLHS).

21 Dec 2016

First large-scale clinical study of long-acting injectable HIV drug begins

The first large-scale clinical trial of a long-acting injectable drug for HIV prevention began today.

21 Dec 2016

Breast cancer patient finds new hope with potentially revolutionary treatment

City of Hope patient Susan Young has had a remarkable response to a potentially revolutionary new treatment, a combination of the p53 cancer vaccine and a drug that blocks a specific cancer-aiding protein.

21 Dec 2016

Early physical activity following concussion linked to lower risk of PPCS

Among children and adolescents who experienced a concussion, physical activity within 7 days of injury compared with no physical activity was associated with reduced risk of persistent postconcussive symptoms at 28 days, according to a study appearing in the December 20 issue of JAMA.

20 Dec 2016

Regular use of common mouthwash can help curb spread of gonorrhoea infections

A commercial brand of mouthwash that is readily available from supermarkets and pharmacies can help curb the growth of the bacteria responsible for gonorrhoea, reveals preliminary research published online in the journal Sexually Transmitted Infections.

20 Dec 2016

Bionic pancreas system manages blood sugar levels in patients with type 1 diabetes living at home

The bionic pancreas system developed by Boston University investigators proved better than either conventional or sensor-augmented insulin pump therapy at managing blood sugar levels in patients with type 1 diabetes living at home, with no restrictions, over 11 days.

20 Dec 2016

How can we tackle antimicrobial resistance?

Antimicrobial resistance happens when bugs, like bacteria, fungi or viruses, change, or evolve, when they’re exposed to drugs, like antibiotics, antifungals, or antivirals. Bugs that develop antimicrobial resistance are sometimes referred to as ‘superbugs’.

20 Dec 2016

Low-carbohydrate diet may help reverse inherited intellectual disability linked to Kabuki syndrome

Experimenting on mice with a genetic change similar to that found in people with a rare inherited disease called Kabuki syndrome, Johns Hopkins scientists report that a very low-carbohydrate diet can "open up" DNA and improve mental function.

20 Dec 2016

Regular NSAID use linked to increased risk of endometrial cancer mortality

Regular use of over-the-counter non-steroidal inflammatory drugs such as aspirin and ibuprofen is associated with an increased risk of dying in patients diagnosed with Type 1 endometrial cancers, according to a new population-based study led by The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

20 Dec 2016

Clinical Trial News and Research

FDA approves first drug to treat children and adults with spinal muscular atrophy

UCLA-led research finds promising results for more personalized head and neck cancer treatment

New Philips HealWell lighting system supports sleep, improves patient experience in healthcare facilities

New computational tool can predict personal cancer driver genes to optimize treatment

Generative AAE can be radically new way to discover drugs on demand

Heart attack risk for people with HIV nearly 50% higher than predicted

Researchers engineer promising live-attenuated RSV vaccine candidate

Clinical study tests adult stem cell therapy for infants with congenital HLHS

First large-scale clinical study of long-acting injectable HIV drug begins

Breast cancer patient finds new hope with potentially revolutionary treatment

Early physical activity following concussion linked to lower risk of PPCS

Regular use of common mouthwash can help curb spread of gonorrhoea infections

Bionic pancreas system manages blood sugar levels in patients with type 1 diabetes living at home

How can we tackle antimicrobial resistance?

Low-carbohydrate diet may help reverse inherited intellectual disability linked to Kabuki syndrome

Regular NSAID use linked to increased risk of endometrial cancer mortality

Landmark clinical trial to test third investigational drug for Alzheimer's disease

Combination therapy holds great promise to clear precancerous skin lesions

New clinical study for children with AML aims to kill leukemia cells and minimize cardiac damage

Researchers develop promising therapeutic antibodies against tumor-promoting MMPs

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