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Key mechanism that increases drug tolerance among microbial communities revealed

Research from the Francis Crick Institute has revealed a key mechanism which increases tolerance to drugs amongst microbial communities.

22 Mar 2022

Immunocompromised patients worry vaccine exemptions put them in peril

Charlie O'Neill received part of her husband's liver in a 2013 living donor transplant and has been taking drugs that suppress her immune system ever since to prevent her body from attacking the organ.

22 Mar 2022

Posaconazole found to be effective as a small molecule fusion inhibitor against SARS-CoV-2 variants

Researchers evaluated the importance of the Ex3Lx6L motif in SARS-CoV-2 entry into host cells mediated by the spike protein syncytium formation and membrane fusion.

22 Mar 2022

Closed Loop Medicine announces completion of precision medicine clinical trial for patients with high blood pressure

Closed Loop Medicine Ltd announced today that the last patient has completed participation in a clinical trial investigating the Company’s integrated precision care product solution for patients with hypertension.

22 Mar 2022

Association between seropositivity and comorbidities after COVID-19 vaccination

In a recent study posted to the medRxiv* preprint server, researchers demonstrated that comorbidities attenuated the chance of seropositivity following coronavirus disease 2019 (COVID-19) vaccination.

22 Mar 2022

Is COVID-19 on the verge of ending?

Researchers explore the changes arising in SARS-CoV-2 over time.

21 Mar 2022

Antimalarial drugs are also effective at treating a pulmonary disease, study finds

A research team at Colorado State University has discovered that drugs used to treat malaria are also effective at treating a pulmonary disease similar to tuberculosis.

21 Mar 2022

Researchers win NIH grant to treat human brain cancer with a drug previously used on canines

The National Institutes of Health is awarding a $3.8 million grant to John Rossmeisl, the Dr. and Mrs. Dorsey Taylor Mahin Professor of Neurology and Neurosurgery at the Virginia-Maryland College of Veterinary Medicine, and Waldemar Debinski, cancer biology professor at the Wake Forest School of Medicine.

21 Mar 2022

Using CRISPR/Cas to develop biosafety materials

Researchers discuss the use of the highly efficient CRISPR/Cas technologies to identify viral genome sequences for biosafety purposes.

21 Mar 2022

Researchers offer a clear picture of how the 9-1-1 clamp is recruited to sites of DNA damage

DNA is often likened to a blueprint. The particular sequence of As, Cs, Gs, and Ts in DNA provides information for building an organism.

21 Mar 2022

Oral drug that reverses immune aging effectively prevents death in COVID-19 mouse model

The immune system deteriorates with age, making COVID-19 particularly deadly in older people - but to date, no clinically available medication addresses this key risk factor.

21 Mar 2022

New insight into genetic mechanisms that control appetite and energy metabolism early in life

Have you ever wondered why it is so different how quickly and how much small babies put on weight during the first years of life? Now researchers at the University of Bergen in Norway have found that this is largely controlled by our genes.

21 Mar 2022

Researchers find effective nutritional strategies to prevent acute kidney injury

A research team led by Professor Dr Roman-Ulrich Müller has established that four out of six different nutritional strategies prevent acute kidney injury in the mouse model.

21 Mar 2022

Mount Sinai Health System launches new Alopecia Areata Center of Excellence

In an unparalleled effort to deliver outstanding comprehensive care and to employ revolutionary approaches to novel therapeutics around the skin condition alopecia areata, the Mount Sinai Health System has launched the Alopecia Areata Center of Excellence.

21 Mar 2022

TTUHSC secures $1.87 million grant to investigate the impact of vitamin A depletion on Alzheimer’s disease

Ongoing research suggests that an accumulation of toxic reactive oxygen species (ROS) in the area of the brain known as the hippocampal dentate gyrus may begin early on in patients with Alzheimer's disease.

21 Mar 2022

Study explores novel antiviral activity of PAD inhibitors against human beta-coronaviruses HCoV-OC43 and SARS-CoV-2

In a new study, researchers aimed to determine if peptidyl-arginine deiminases inhibitors may be used as a novel class of host-targeting antivirals against human coronaviruses.

21 Mar 2022

Study explores decline in tuberculosis cases during COVID-19 pandemic in the United States

Researchers analyzed a pharmacy dataset to evaluate the 20% decrease in tuberculosis cases reported in 2020 by the US National Tuberculosis Surveillance System.

21 Mar 2022

Pfizer CEO pushes yearly shots for covid. Not so fast, experts say.

When Pfizer CEO Albert Bourla said March 13 that all Americans would need a second booster shot, it struck many covid experts as a self-serving remark without scientific merit. It also set off spasms of doubt over the country's objectives in its fight against the coronavirus.

21 Mar 2022

Study unveils several natural marine products as potential agents against SARS-CoV-2

A recent study, published in the Journal of Natural Products of the American Chemical Society and American Society of Pharmacognosy, highlighted three natural marine products as potent inhibitors of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – without any apparent toxic effects for human lung cells.

21 Mar 2022

HRR mutational status associated with survival outcomes in recurrent platinum-sensitive ovarian cancer

Results of a biomarker analysis of the NRG Oncology NRG-GY004 trial were presented at a Seminal Session during the Society for Gynecologic Oncology's (SGO) Annual Meeting on Women's Cancer in March 2022.

19 Mar 2022

Drugs News and Research

Key mechanism that increases drug tolerance among microbial communities revealed

Immunocompromised patients worry vaccine exemptions put them in peril

Posaconazole found to be effective as a small molecule fusion inhibitor against SARS-CoV-2 variants

Closed Loop Medicine announces completion of precision medicine clinical trial for patients with high blood pressure

Association between seropositivity and comorbidities after COVID-19 vaccination

Is COVID-19 on the verge of ending?

Antimalarial drugs are also effective at treating a pulmonary disease, study finds

Researchers win NIH grant to treat human brain cancer with a drug previously used on canines

Using CRISPR/Cas to develop biosafety materials

Researchers offer a clear picture of how the 9-1-1 clamp is recruited to sites of DNA damage

Oral drug that reverses immune aging effectively prevents death in COVID-19 mouse model

New insight into genetic mechanisms that control appetite and energy metabolism early in life

Researchers find effective nutritional strategies to prevent acute kidney injury

Mount Sinai Health System launches new Alopecia Areata Center of Excellence

TTUHSC secures $1.87 million grant to investigate the impact of vitamin A depletion on Alzheimer’s disease

Study explores novel antiviral activity of PAD inhibitors against human beta-coronaviruses HCoV-OC43 and SARS-CoV-2

Study explores decline in tuberculosis cases during COVID-19 pandemic in the United States

Pfizer CEO pushes yearly shots for covid. Not so fast, experts say.

Study unveils several natural marine products as potential agents against SARS-CoV-2

HRR mutational status associated with survival outcomes in recurrent platinum-sensitive ovarian cancer

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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