Inflammation News and Research

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Researchers discover a new way to limit inflammation from adjuvants in vaccines

Adjuvants are a key ingredient of many modern vaccines, working to unleash an immune response that helps protect the body from disease. Many scientists believe that adjuvants are they key to developing new kinds of vaccines for hard-to-vaccinate viruses, like HIV.

9 Sep 2020

Common diabetes drug controls aspects of inflammation in mice

The diabetes drug metformin--derived from a lilac plant that's been used medicinally for more than a thousand years--has been prescribed to hundreds of millions of people worldwide as the frontline treatment for type 2 diabetes.

9 Sep 2020

Scientists shed new light on gene regulatory pathways activated by stress hormone

Scientists have long known that chronic stress experienced early in life, or even chronic prenatal exposure to maternal stress hormones in the womb, can shorten lifespan and contribute to age-related chronic diseases like arthritis, asthma, cancer, cardiovascular disease, diabetes and even mental illness later in life -- long after the source of stress has been removed.

9 Sep 2020

Host gene editing main driving force of SARS-CoV-2 mutations

A new study published on the aRxiv preprint server in September 2020 shows that the host immune response, mediated by two RNA editors, causes the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to adapt and change strain characteristics.

9 Sep 2020

Scientists explain why men are at higher risk from COVID-19

Published in the journal PLOS Biology, the study aimed to provide a better understanding of the mechanisms that drive the varying responses of the infected individuals among different patient demographics, including sex and age.

9 Sep 2020

Researchers discuss the role of chemical senses in disease and social interactions in humans, animals

Across 5 days in August (3rd-7th), scientists from around the world gathered virtually to present and discuss new information on the role of the chemical senses in disease, nutrition, and social interactions in humans and animals.

9 Sep 2020

COVID-19 in pregnancy doubles odds of preterm delivery

The COVID-19 pandemic is continuing to cause huge social, economic, and health-related costs throughout the world, especially in Spain. Clinicians are still coming to terms with the range of health conditions wrought by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A new study published on the preprint server medRxiv* in September 2020 shows that this infection results in fetal and maternal complications.

9 Sep 2020

Memory B cells indicate durable immunity in COVID-19

Now a new study by researchers at SUNY Upstate Medical University and published recently on the preprint server medRxiv in September 2020 shows that memory B cells are upregulated in convalescent COVID-19 patients, correlating with a better immune response and shorter symptom duration.

8 Sep 2020

Microglia-targeting nanotherapeutics for treatment of neurodegenerative disorders

Inspired by the need for new and better therapies for neurodegenerative diseases, such as Parkinson's disease and Alzheimer's disease, Rutgers University researchers are exploring the link between uncontrolled inflammation within the brain and the brain's immune cells, known as microglia.

8 Sep 2020

Scientists discover tissue reparative role for a rare immune cell type in the gut

Scientists from King's College London have discovered an unexpected tissue reparative role for a rare immune cell type in the gut that could tip toward fibrosis or cancer if dysregulated.

8 Sep 2020

Ghrelin may help protect the elderly population from muscle loss

The hormone, ghrelin, may help protect the elderly population from muscle loss, according to a study being presented at e-ECE 2020. The study found that administering a particular form of ghrelin to older mice helped to restore muscle mass and strength.

8 Sep 2020

Study addresses the role of macrophage activation syndrome in COVID-19

Scientists review macrophage activation syndrome — a feature of the cytokine storm that kills patients with severe cases of COVID-19, as well as possible treatments.

8 Sep 2020

Study links brain astrocyte dysfunction to Parkinson’s disease pathology

A new study using induced pluripotent stem cell technology links astrocyte dysfunction to Parkinson’s disease pathology.

8 Sep 2020

Limited gut inflammation in COVID-19

A new study by researchers at the Icahn School of Medicine at Mount Sinai and published on the preprint server medRxiv in September 2020 shows that gut infection with this virus produces primarily mucosal immunity but also a limited inflammatory response.

8 Sep 2020

Consortium compiles recommendations for measuring HIV reservoir size in cure-directed studies

Spearheaded by scientists at The Wistar Institute, top worldwide HIV researchers from the BEAT-HIV Martin Delaney Collaboratory to Cure HIV-1 Infection by Combination Immunotherapy compiled the first comprehensive set of recommendations on how to best measure the size of persistent HIV reservoirs during cure-directed clinical studies.

7 Sep 2020

A potential new way of treating Alzheimer’s Disease

In this interview, Dr. Brad. L. Heckman speaks to News-Medical about a new pathway that could potentially treat Alzheimers disease.

7 Sep 2020

D-dimer - A sensitive novel biomarker of COVID-19 mortality

Now, a new study published on the preprint server medRxiv* reports the use of D-dimer in predicting the risk of mortality in COVID-19.

7 Sep 2020

Rehabilitation speeds coronavirus recovery

Now, a team of researchers at the University Clinic in Innsbruck in Austria has found that the long-term lung and heart damage in coronavirus disease (COVID-19) patients who recovered tend to improve over time.

7 Sep 2020

Study: Patients with thyroid inflammation may be at greater risk of developing anxiety

Patients with autoimmune inflammation of their thyroid may be at greater risk of developing anxiety, according to a study being presented at e-ECE 2020.

7 Sep 2020

MIS-C linked to COVID-19 damages children's hearts

Multisystem inflammatory syndrome in children (MIS-C), believed to be linked to COVID-19, damages the heart to such an extent that some children will need lifelong monitoring and interventions, said the senior author of a medical literature review published Sept. 4 in EClinicalMedicine, a journal of The Lancet.

5 Sep 2020