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Whole genome study identifies genetic architecture for diagnosis of polycystic ovary syndrome

In the largest genetic analysis of polycystic ovary syndrome (PCOS) performed to date, an international consortium, including researchers at the Icahn School of Medicine at Mount Sinai, conducted a whole genome association study to identify common genetic architecture for different diagnostic criteria used to define the syndrome.

24 Dec 2018

Implementation of HRRP program associated with increased mortality after discharge

The Hospital Readmissions Reduction Program (HRRP) was created under the Affordable Care Act and hospitals face financial penalties for higher-than-expected 30-day readmission rates for patients with heart failure, heart attack and pneumonia.

24 Dec 2018

Researchers identify hundreds of new genes linked to blindness in lab mice

Hundreds of new genes linked to blindness and other vision disorders have been identified in a screen of mouse strains. Many of these genes are likely important in human vision and the results could help identify new causes of hereditary blindness in patients.

24 Dec 2018

CWRU researcher receives nearly $1 million to study drug resistance mechanisms in prostate cancer

Sanjay Gupta, PhD, of Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center will receive $962,000 over three years to investigate drug resistance mechanisms in prostate cancer.

24 Dec 2018

Study reveals how Hepatitis C infection varies by state and region

Hepatitis C virus infection is a major cause of illness and death in the United States and injection drug use is likely fueling many new cases.

24 Dec 2018

Glial cell maturation is severely impaired in patients with Huntington's disease

The neurological disorder Huntington's disease causes behavioral and motor changes, which among other things are a result of dysfunctional maturation or formation of glial cells, the brain's support cells, researchers from the University of Copenhagen demonstrate in a new study based on mice trials.

24 Dec 2018

Risk of heart attack and stroke is high in the months before cancer diagnosis, shows study

Older adults with cancer are more likely to have had a heart attack or stroke in the months prior to their cancer diagnosis compared with similar adults who do not have cancer during the same period, according to a report published online today in Blood. Lung and colon cancers, as well as advanced-staged cancers, appear to be most strongly associated with an elevated risk of heart attack and stroke caused by blood clots in the arteries.

24 Dec 2018

Research identifies factors that help dementia patients and their carers to live well

New research has identified the factors that enable people with dementia and their carers to live as well as possible.

24 Dec 2018

Soyasapogenol B: A new drug delivery technology for therapeutics

Multi-Walled Carbon Nanotubes (MWCNTs) are characterized by walls formed by a one atom thick sheet of carbon.

24 Dec 2018

Study reveals how molecular mechanisms regulate lysosomal exocytosis by phagocytes

Lysosomes are filled with more than 50 different hydrolytic enzymes, which are capable of digesting most cellular components.

23 Dec 2018

Statins reduce the formation of brown adipose tissue

A certain proportion of the adult population has not only white adipose (or fatty) tissue, but also the brown kind. This brown adipose tissue helps to convert sugar and fat into heat. People with brown adipose tissue are better at regulating their body temperature in the winter, and are less likely to suffer from excess weight or diabetes.

21 Dec 2018

Finding ways to reduce head impacts in youth football

The high head impact and concussion rates in football are of increasing concern, especially for younger players.

21 Dec 2018

New treatment for adults with rare, life-threatening blood disease receives FDA approval

The U.S. Food and Drug Administration today approved Ultomiris (ravulizumab) injection for the treatment of adult patients with paroxysmal nocturnal hemoglobinuria (PNH), a rare and life-threatening blood disease.

21 Dec 2018

Refund on the way to latest ‘Bill of the Month’ patient

Sarah Witter had to pay for a second surgery to repair her broken leg after a metal plate installed during the first surgery broke. On Friday, she got a more welcome break — a $6,358.26 refund from the hospital and her insurer.

21 Dec 2018

Study shows high rates of antibiotic overuse in patients undergoing common urological procedures

A new study suggests that antibiotics are being overused in up to 60 percent of patients undergoing common urological procedures.

21 Dec 2018

Hospital readmission reduction program associated with increase in post-discharge mortality

A policy designed to reduce hospital readmissions through financial penalties was associated with a significant increase in post-discharge mortality for patients with heart failure and pneumonia, according to a large-scale study by researchers in Beth Israel Deaconess Medical Center's Smith Center for Outcomes Research in Cardiology.

21 Dec 2018

Research News and Research

Whole genome study identifies genetic architecture for diagnosis of polycystic ovary syndrome

Implementation of HRRP program associated with increased mortality after discharge

Researchers identify hundreds of new genes linked to blindness in lab mice

CWRU researcher receives nearly $1 million to study drug resistance mechanisms in prostate cancer

Study reveals how Hepatitis C infection varies by state and region

Glial cell maturation is severely impaired in patients with Huntington's disease

Risk of heart attack and stroke is high in the months before cancer diagnosis, shows study

Research identifies factors that help dementia patients and their carers to live well

Soyasapogenol B: A new drug delivery technology for therapeutics

Study reveals how molecular mechanisms regulate lysosomal exocytosis by phagocytes

Statins reduce the formation of brown adipose tissue

Finding ways to reduce head impacts in youth football

New treatment for adults with rare, life-threatening blood disease receives FDA approval

Refund on the way to latest ‘Bill of the Month’ patient

Study shows high rates of antibiotic overuse in patients undergoing common urological procedures

Hospital readmission reduction program associated with increase in post-discharge mortality

Study examines opioid prescribing rates for pediatric patients in EDs

Study explores causes for rising rate of hospitalizations among homeless individuals

FDA approves new treatment for rare disease of the bone marrow and blood

Massachusetts stroke patient receives ‘outrageous’ $474,725 medical flight bill

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