Hormone News and Research

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A hormone is a chemical released by one or more cells that affects cells in other parts of the organism. Only a small amount of hormone is required to alter cell metabolism. It is essentially a chemical messenger that transports a signal from one cell to another.

FDA invites Amgen for ODAC meeting on XGEVA sBLA to treat castration-resistant prostate cancer

Amgen today announced the U.S. Food and Drug Administration has invited the Company to participate in a meeting of the Oncologic Drugs Advisory Committee (ODAC) on Feb. 8, 2012 to discuss the supplemental Biologics License Application (sBLA) for XGEVA (denosumab) to treat men with castration-resistant prostate cancer (CRPC) at high risk of developing bone metastases.

30 Dec 2011

Fatty food and brain damage: Study finds connection

US scientists found a sudden change to a high-fat diet triggered inflammation in a key area of rodent brains responsible for regulating body weight. The inflammation produced distinctive scarring similar to that seen in stroke patients - and that brain scarring was then observed in humans who were overweight.

28 Dec 2011

Scientists identify molecular player critical to proper working of important health proteins

Half the drugs used today target a single class of proteins - and now scientists have identified an important molecular player critical to the proper workings of those proteins critical to our health.

28 Dec 2011

Researchers analyze link between maternal-child relationship and adolescent obesity

The quality of the emotional relationship between a mother and her young child could affect the potential for that child to be obese during adolescence, a new study suggests.

26 Dec 2011

Pfizer, Karo Bio partner to develop RORgamma modulators for autoimmune diseases

Karo Bio AB has entered into a research collaboration agreement with Pfizer Inc., to discover and develop novel small molecule RORgamma modulators for the treatment of autoimmune diseases.

26 Dec 2011

Correcting anemia can preserve kidney function in many transplant recipients

Correcting anemia, a red blood cell deficiency, can preserve kidney function in many kidney transplant recipients, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology.

23 Dec 2011

Consistent evidence that HRT use associated with breast cancer

McMaster University researchers have found consistent evidence that use of hormone replacement therapy (HRT) is associated with breast cancer globally.

22 Dec 2011

Fetal heart rate monitor may improve infant's health

Despite the numerous medical advances that happen every day, the infant mortality rate in the United States is still higher than most European countries. While experts believe this is closely linked to the growing rate of pre-term births, researchers are committed to finding ways to make labor and delivery safer. Northwestern Medicine- researchers are examining a new device that may support improved newborn health at delivery through closer monitoring of infant oxygen use during labor.

22 Dec 2011

Effects of allopregnanolone in women with severe pre-menstrual syndrome

Sensitivity to allopregnanolone, a hormone that occurs naturally in the body after ovulation and during pregnancy, changes during the course of the menstrual cycle and is different in women with severe pre-menstrual syndrome (PMS) compared with women without PMS complaints. This has been shown by Erika Timby in her doctoral dissertation recently defended at Umeå University, Sweden.

22 Dec 2011

Study hopes to explain premature births and failed inductions of labour

New research hopes to explain premature births and failed inductions of labour. The study by academics at the University of Bristol suggests a new mechanism by which the level of myosin phosphorylation is regulated in the pregnant uterus.

22 Dec 2011

Truths and myths about pregnancy, obesity

Ironically, despite excessive caloric intake, many obese women are deficient in vitamins vital to a healthy pregnancy. This and other startling statistics abound when obesity and pregnancy collide. Together, they present a unique set of challenges that women and their doctors must tackle in order to achieve the best possible outcome for mom and baby.

22 Dec 2011

Mother's milk for healthy growth

A PhD project from LIFE - the Faculty of Life Sciences at the University of Copenhagen has shown that breastfed children follow a different growth pattern than non-breastfed children. Breastfeeding lowers the levels of the growth hormones IGF-I and insulin in the blood, which means that growth is slightly slower. This is believed to reduce the risk of overweight and diabetes later in life.

21 Dec 2011

Takeda receives FDA approval for EDARBYCLOR to treat hypertension

Takeda Pharmaceutical Company Limited and its wholly-owned subsidiary, Takeda Pharmaceuticals North America, Inc., announced that the U.S. Food and Drug Administration (FDA) approved EDARBYCLOR (azilsartan medoxomil and chlorthalidone) for the treatment of hypertension to lower blood pressure in adults.

21 Dec 2011

Mammography appears to detect women with low-risk breast cancer

As a woman ages, her chances of being diagnosed with a lower-risk breast tumor increase, according to a novel study led by UCSF which found that for women over 50, a substantial number of cancers detected by mammograms have good prognoses.

20 Dec 2011

DHEA hormone may help a woman's menopausal symptoms, sex life

A new study has shown that the DHEA, a hormone mostly secreted by the adrenal glands, may be able to help a woman's menopausal symptoms, as well as giving her a better sex life.

20 Dec 2011

Scientists discover missing link between body's biological clock and sugar metabolism system

Scientists have discovered a missing link between the body's biological clock and sugar metabolism system, a finding that may help avoid the serious side effects of drugs used for treating asthma, allergies and arthritis.

20 Dec 2011

Weight loss pill without major side effects coming soon

Scientists are on their way to develop a perfect diet pill. The drug, which switches off appetite using hormones that are created naturally in the stomach when it is full, could be the first to be effective in weight loss without side effects.

19 Dec 2011

Smoking in women associated with skin cancer: Study

A new study has found a link between tobacco use and skin cancer especially in women. The study found that women who had squamous cell skin cancer were more likely to have smoked than those who were free from the disease. And those who smoked at least 20 years were twice as likely to develop squamous cell skin cancer - a less aggressive form of skin cancer as melanoma.

19 Dec 2011

Many maternal deaths from pre-eclampsia in the UK linked with substandard care

An editorial published this week in the Lancet online highlights the shocking fact that many maternal deaths in the UK are associated with substandard care and are potentially preventable.

17 Dec 2011

Researchers discover miR-520 blocks cancer-promoting signaling pathway

MicroRNAs or miRNAs are tiny RNA molecules that have only about 20 nucleotides and do not code for proteins. They regulate many important processes in cells by binding to target messenger RNAs - the instructions for protein production -, thus blocking production of the respective protein. In cancer, the production of some miRNAs is often reduced or amplified. This particularly affects miRNAs that regulate the activity of cancer-promoting genes.

17 Dec 2011