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New study helps better understand how type 2 diabetes progresses as a disease

Researchers at Joslin Diabetes Center, an affiliate of Harvard Medical School, have unlocked the key to clearly identifying diseased beta cells in type 2 diabetes.

1 Oct 2019

Researchers identify new genetic signals for regulation of infant growth

Researchers at the University of Bergen in Norway have identified new genetic signals for the regulation of how infants grow. This may be a crucial step in the fight against growth-related diseases.

1 Oct 2019

Heart failure medication often prescribed in lower dosages than recommended

Important medication for the treatment of heart failure are often prescribed in lower dosages than recommended by international guidelines.

1 Oct 2019

Analyses of two clinical trials predict response to asthma drug by COPD patients

Chronic obstructive pulmonary disease, or COPD, is the third leading cause of death in the U.S., according to the American Lung Association.

30 Sep 2019

Carnegie biologists discover possible therapeutic target for slow healing of aged muscles

An age-related decline in recovery from muscle injury can be traced to a protein that suppresses the special ability of muscle stem cells to build new muscles, according to work from a team of current and former Carnegie biologists led by Chen-Ming Fan and published in Nature Metabolism.

30 Sep 2019

Triplet therapy could benefit patients with BRAF-mutant metastatic colorectal cancer

Results presented today at the ESMO Congress 2019, Barcelona 27 September - 01 October, during the second Proffered Paper Session on Gastrointestinal tumors (colorectal) by VHIO's Director, Josep Tabernero, show that the triplet combination of the BRAF inhibitor, encorafenib, MEK inhibitor, binimetinib, and EGFR inhibitor, cetuximab, not only significantly improves overall survival but also increases objective response rates compared with standard of care in patients with BRAF V600E-mutant metastatic colorectal cancer.

30 Sep 2019

New trial shows improved survival for patients with advanced colorectal BRAF-mutant cancer

A clinical trial has shown that using a combination of three drugs that target a BRAF gene mutation in patients with mCRC effectively boosts overall survival.

30 Sep 2019

Stem cells derived from patients could lead to new treatments for congenital muscular dystrophies

Researchers at Queen Mary University of London and University College London have shown that using stem cells derived from patients could help find new treatments for a group of congenital muscular dystrophies.

30 Sep 2019

New screening test detects 20 types of cancer

Researchers from the Dana-Farber Cancer Institute have developed a new blood test that would accurately determine the presence of several types of cancers. The results of their multi-centre clinical trial to prove the effectiveness of their test was presented by the researchers at the European Society for Medical Oncology (ESMO) 2019 Congress in Barcelona, Spain, on the 28th of September 2019.

30 Sep 2019

Adding targeted therapy drug to standard treatment benefits aggressive breast cancer patients

A study led by UCLA researchers found that adding ribociclib, a targeted therapy drug, to standard hormone therapy has been shown to significantly improve overall survival in postmenopausal women with advanced hormone-receptor positive/HER2- breast cancer, one of the most common forms of the disease.

29 Sep 2019

New blood test shows ability to accurately detect numerous types of cancer

A new blood test in development has shown ability to screen for numerous types of cancer with a high degree of accuracy, a trial of the test shows.

28 Sep 2019

Lipid produced in response to cold helps reduce blood sugar

Researchers based in Brazil, the United States and Germany have discovered that 12-HEPE, a lipid produced in response to cold by brown adipose tissue in the human body, helps reduce blood sugar. The results of their experiments with mice pave the way for new treatments for diabetes.

27 Sep 2019

Rice chemist explores how extra amino acid could be used to make life-saving substances

There are 20 amino acids in the standard genetic code. A Rice University professor wants to know what one can do with 21.

27 Sep 2019

Lifelong choline supplementation holds potential to prevent Alzheimer's disease

In a new study, Biodesign researchers reveal that a lifelong dietary regimen of choline holds the potential to prevent Alzheimer's disease.

27 Sep 2019

Study may help scientists to learn more about the causes of chronic pain

Researchers from North Carolina State University have found that inflammation increases neuronal activity, gene expression and sensory nerve (neurite) outgrowth in neurons involved in thermal - but not physical- sensations in mice.

27 Sep 2019

Cancer Research Institute declares 2019 recipients of top scientific and philanthropic awards

The Cancer Research Institute (CRI), a nonprofit organization dedicated to advancing the discovery and development of powerful immunotherapies for all forms of cancer, has announced the 2019 recipients of its highest scientific and philanthropic awards.

27 Sep 2019

FDA warns about Ranitidine containing known carcinogen NDMA

The United States Food and Drug Administration have issued a warning regarding some substances present in a brand of Ranitidine that could be carcinogenic. In their first warning issued on the 13th of this month, the FDA warns that one of the brands of Ranitidine, Zantac is said to contain a nitrosamine impurity called N-nitrosodimethylamine (NDMA) at low levels. NDMA is a known carcinogen, the report reads based on lab data and is also found in the environment, food and water the report adds.

26 Sep 2019

Receptor News and Research

New study helps better understand how type 2 diabetes progresses as a disease

Researchers identify new genetic signals for regulation of infant growth

Heart failure medication often prescribed in lower dosages than recommended

Analyses of two clinical trials predict response to asthma drug by COPD patients

Carnegie biologists discover possible therapeutic target for slow healing of aged muscles

Triplet therapy could benefit patients with BRAF-mutant metastatic colorectal cancer

New trial shows improved survival for patients with advanced colorectal BRAF-mutant cancer

Stem cells derived from patients could lead to new treatments for congenital muscular dystrophies

New screening test detects 20 types of cancer

Adding targeted therapy drug to standard treatment benefits aggressive breast cancer patients

New blood test shows ability to accurately detect numerous types of cancer

Lipid produced in response to cold helps reduce blood sugar

Rice chemist explores how extra amino acid could be used to make life-saving substances

Lifelong choline supplementation holds potential to prevent Alzheimer's disease

Study may help scientists to learn more about the causes of chronic pain

Cancer Research Institute declares 2019 recipients of top scientific and philanthropic awards

FDA warns about Ranitidine containing known carcinogen NDMA

Children's of Alabama using cold sore virus to fight pediatric brain cancer

Clinical trial to evaluate efficacy and safety of new treatment for giant cell arteritis

Johns Hopkins researchers identify new way to lower blood pressure in obese patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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