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UVA Cancer Center receives $250,000 to develop innovative new approach to treating leukemia

Children's Cancer Research Fund has awarded $250,000 to an innovative new approach to treating leukemia – blood cancer – being developed at UVA Cancer Center.

18 May 2023

Researchers find that SARS-CoV-2 directly infects hepatocytes that cause hyperglycemia

Researchers investigate whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused hyperglycemia.

18 May 2023

UK’s first Centre for Phage Research highlights Actiphage in the KTN UK Phage Innovation Showcase

Tuberculosis is caused by a bacterium that has evolved to evade the body’s immune system; now, its natural enemy, a phage, is being used to detect the infection at an early stage.

18 May 2023

OncoAssure announces results of clinical study on novel prostate cancer test

OncoAssure today announced that results of its clinical study validating OncoAssure Prostate, a novel test for prostate cancer management, have been published in European Urology Focus, a peer-reviewed and open access journal.

17 May 2023

How the gut microbiome supports iron uptake by intestinal regulatory T-cells

Research paper discusses the relationship between iron deficiencies and immune tolerance in patients with inflammatory bowel disease. The study shows that high cellular iron levels fostered by pentanoate, a short-chain fatty acid produced by intestinal microbiota, are necessary for the homeostasis of regulatory T cells in the intestine, and iron deficiencies in Treg can result in lethal autoimmune disease.

17 May 2023

Novel computational platform can expand the pool of cancer immunotherapy targets

Researchers at Children's Hospital of Philadelphia (CHOP) and the University of California, Los Angeles (UCLA) have developed a computational platform capable of discovering tumor antigens derived from alternative RNA splicing, expanding the pool of cancer immunotherapy targets.

17 May 2023

Researchers identify a major stem cell variant in lungs of patients with idiopathic pulmonary fibrosis

A pair of internationally renowned stem cell cloning experts at the University of Houston is reporting their findings of variant cells in the lungs of patients with Idiopathic Pulmonary Fibrosis (IPF) which likely represent key targets in any future therapy for the condition.

17 May 2023

Democratizing RNA sequencing: A breakthrough in cost and efficiency

CSEM has supported the Lausanne-based start-up Alithea Genomics in developing a technology capable of processing hundreds of ribonucleic acid (RNA) samples in a single tube, which translates to a significant reduction in reagents and manual effort in the overall workflow.

From CSEM 17 May 2023

Novel antibodies target human receptors to neutralize SARS-CoV-2 variants and future sarbecoviruses

Researchers generated six human monoclonal antibodies that prevented infection.

17 May 2023

Reviving a forgotten antibiotic: Old drug shows new promise against superbugs

Research discusses the activity spectrum of nourseothricin and its components, S-F and S-D, against drug-resistant, gram-negative pathogens. S-F showed promising activity against NDM-1-expressing Klebsiella pneumoniae Nevada strain with minimal toxicity, and it probes the A-decoding site potentially accounting for its miscoding activity.

17 May 2023

Study establishes a mechanistic link between obesity and oral cancer immune escape

A team from the University of Michigan Rogel Cancer Center and School of Dentistry, led by Yu Leo Lei, D.D.S., Ph.D., have identified a mechanism in mice for how obesity affects some oral cancers' ability to escape from the immune system.

16 May 2023

Glycosylation enzyme plays a crucial role in brain development, study shows

The MGAT5 glycosylation enzyme plays a crucial role in brain development, according to a study by University of California, Irvine researchers, a discovery that may contribute to new therapeutic purposes for neural stem cells.

16 May 2023

Researchers may have identified a molecular cause for memory changes in early childhood

How do our brains become capable of creating specific memories? In one of the first preclinical studies to examine memory development in youth, a research team at The Hospital for Sick Children (SickKids) may have identified a molecular cause for memory changes in early childhood.

16 May 2023

Long-ignored antibiotic could help fight against multi-drug resistant bacteria

"The end of modern medicine as we know it." That's how the then-director general of the World Health Organization characterized the creeping problem of antimicrobial resistance in 2012.

16 May 2023

"Smart" sutures can detect inflammation and release drugs

Inspired by sutures developed thousands of years ago, MIT engineers have designed "smart" sutures that can not only hold tissue in place, but also detect inflammation and release drugs.

16 May 2023

Machine learning reveals sex-specific Alzheimer's risk genes

Research explores sex-specific gene associations in Alzheimer's disease using a machine-learning approach. It reveals immune response pathways in both sexes and stress-response pathways in males, highlighting potential biomarkers and therapeutic targets for personalized treatments.

16 May 2023

B Cell News and Research

UVA Cancer Center receives $250,000 to develop innovative new approach to treating leukemia

Researchers find that SARS-CoV-2 directly infects hepatocytes that cause hyperglycemia

UK’s first Centre for Phage Research highlights Actiphage in the KTN UK Phage Innovation Showcase

OncoAssure announces results of clinical study on novel prostate cancer test

How the gut microbiome supports iron uptake by intestinal regulatory T-cells

Novel computational platform can expand the pool of cancer immunotherapy targets

Researchers identify a major stem cell variant in lungs of patients with idiopathic pulmonary fibrosis

Democratizing RNA sequencing: A breakthrough in cost and efficiency

Novel antibodies target human receptors to neutralize SARS-CoV-2 variants and future sarbecoviruses

Reviving a forgotten antibiotic: Old drug shows new promise against superbugs

Study establishes a mechanistic link between obesity and oral cancer immune escape

Glycosylation enzyme plays a crucial role in brain development, study shows

Researchers may have identified a molecular cause for memory changes in early childhood

Long-ignored antibiotic could help fight against multi-drug resistant bacteria

"Smart" sutures can detect inflammation and release drugs

Machine learning reveals sex-specific Alzheimer's risk genes

Mast cells play a crucial role in the development of chronic myeloid leukemia

Molecular mechanism behind a DNA repair pathway revealed

Researchers discover key epigenetic alteration associated with clinical course of liver cancer

New process for automated and highly accurate reporting of NGS-based clonality testing

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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