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Protection against SARS-CoV-2 Omicron variant by hetero-bivalent nanobodies

A new study investigated the broad-spectrum protection provided by hetero-bivalent nanobodies against SARS-CoV-2 variants of concern, such as Omicron.

14 Mar 2022

Researchers develop a system of synthetic biosensors to assess the response of cancer therapy

Immune checkpoint blockade (ICB) inhibitors have transformed the treatment of cancer and have become the frontline therapy for a broad range of malignancies. It's because they work better than the previous standard of care.

11 Mar 2022

Tumor cells’ 'ferroaddiction' can be exploited to deliver powerful anticancer drugs

Researchers at the University of California, San Francisco, have discovered that cells carrying the most common mutation found in human cancer accumulate large amounts of ferrous iron and that this "ferroaddiction" can be exploited to specifically deliver powerful anticancer drugs without harming normal, healthy cells.

11 Mar 2022

Modifying red blood cells to create a promising new vehicle for vaccine delivery

Physicists, chemists and immunologists at McMaster University have teamed up to modify red blood cells to transport viral agents which can safely trigger the immune system to protect the body against SARS-CoV-2, creating a promising new vehicle for vaccine delivery.

11 Mar 2022

Salk professors receive $3 million Endeavor Award to support lung cancer research

Professors Reuben Shaw, Susan Kaech, Christian Metallo and Alan Saghatelian have received a 2022 Mark Foundation for Cancer Research Endeavor Award to support their research exploring the metabolic changes that help lung cancers develop.

11 Mar 2022

Canadian scientist discusses about how society could better prepare for future pandemics

Aled Edwards is of two minds about medicine's response to COVID-19. On one hand, he notes, we had life-saving vaccines and therapies less than a year after the discovery of SARS-CoV-2. On the other, more than six million, and possibly as many as 18 million people have died, and global access to advances that can prevent and treat severe disease remains highly inequitable.

11 Mar 2022

Lower, more frequent doses of nanomedicines may provide additional benefits for cancer patients

Tiny structures called nanoparticles can be used to carry substances to certain parts of the body - for example, to deliver a chemotherapy drug to a tumor.

11 Mar 2022

In silico screening and testing of FDA approved drugs inhibiting SARS-CoV-2 spike protein cleavage

Researchers screened 5,000 Food and Drug Association-approved drugs to identify repurposed drugs targeting SARS-CoV-2 spike protein cleavage at both S1/S2 boundary and S2’.

11 Mar 2022

Meta-analysis finds intensified anticoagulation had no effect on short term mortality among hospitalized COVID-19 patients

A recent systematic review and meta-analysis evaluated the safety and efficacy of intensified anticoagulation therapy in COVID-19 patients.

11 Mar 2022

Study shows SARS-CoV-2 infection induces global alterations of the host endomembrane system

Researchers observed that Golgi fragmentation induced by SARS-CoV-2 facilitates viral trafficking.

11 Mar 2022

Aminoglycoside antibiotic geneticin shows selective antiviral effect against SARS-CoV-2

Researchers elucidated antiviral activities of aminoglycoside geneticin against seven SARS-CoV-2 variants using different cell lines and respiratory tissues.

11 Mar 2022

Researchers solve the structure of large signaling protein involved in emergence of blood cancers

Researchers led by Christopher Garcia of the Ludwig Center at Stanford University have solved the long-sought structure of a large signaling protein involved in responses to infection, inflammation, the generation of immune cells and when dysregulated by mutation - the emergence of blood cancers known as myeloproliferative neoplasms.

11 Mar 2022

New study analyzes COVID-19 outcomes in patients with cancer

If a cancer patient tests positive for COVID-19, are they more likely to become hospitalized from the disease?

10 Mar 2022

Pioneering kidney disease research at Leicester receives a major boost on World Kidney Day

Pioneering research by the University of Leicester into chronic kidney disease has received a major boost on World Kidney Day (10th March 2022) following a generous £1million donation from long-term supporter and kidney health advocate Jimmy Mayer.

10 Mar 2022

Youth with intentional BZD overdoses more likely to have recent doctor-written prescription

A high number of teens and young adults with an overdose involving a benzodiazepine (BZD), like Xanax, or psychostimulant, like Adderall – medications commonly used to treat mental health issues like attention deficit hyperactivity disorder and anxiety disorders – have a recent medical prescription for a BZD or stimulant, according to Rutgers researchers who say physicians need to weigh the risks and benefits of these medications more closely.

10 Mar 2022

Drugs News and Research

Protection against SARS-CoV-2 Omicron variant by hetero-bivalent nanobodies

Researchers develop a system of synthetic biosensors to assess the response of cancer therapy

Tumor cells’ 'ferroaddiction' can be exploited to deliver powerful anticancer drugs

Modifying red blood cells to create a promising new vehicle for vaccine delivery

Salk professors receive $3 million Endeavor Award to support lung cancer research

Canadian scientist discusses about how society could better prepare for future pandemics

Lower, more frequent doses of nanomedicines may provide additional benefits for cancer patients

In silico screening and testing of FDA approved drugs inhibiting SARS-CoV-2 spike protein cleavage

Meta-analysis finds intensified anticoagulation had no effect on short term mortality among hospitalized COVID-19 patients

Study shows SARS-CoV-2 infection induces global alterations of the host endomembrane system

Aminoglycoside antibiotic geneticin shows selective antiviral effect against SARS-CoV-2

Researchers solve the structure of large signaling protein involved in emergence of blood cancers

New study analyzes COVID-19 outcomes in patients with cancer

Pioneering kidney disease research at Leicester receives a major boost on World Kidney Day

Youth with intentional BZD overdoses more likely to have recent doctor-written prescription

KHN’s ‘What the Health?’: Congress shelves covid funding for now

Study examines the safety, efficacy of old 'forgotten' antibiotic for treating resistant bacterial infections

Scientists identify a molecular regulator involved in resistance to breast cancer treatment

'Post-apoptotic pro-metastatic cells' appear to be potential metastasis prevention targets

WVU researchers use machine learning and GIS to predict where COVID-19 testing will be most crucial

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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