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Lupus Research Institute announces this year's Novel Research Grants

As the Lupus Research Institute celebrates its 15th anniversary, the engine of innovation moves forward at accelerated speed with the announcement of this year's Novel Research Grants bringing new talent from a wide diversity of specialties. Each project lives up to the strictest definition of novel – wholly original, never-been-done-before.

19 Feb 2015

Researchers show importance of DNA damage in fine tuning of innate immune system

For the first time scientists from Umeå University show the importance of DNA damage in fine tuning of our innate immune system and hence the ability to mount the optimal inflammatory response to infections and other biological dangers.

18 Feb 2015

From the scent of geranium to cough medicine; A self-assembling catalyst helps to construct complex biological scaffolds

With great elegance nature builds up complex structures from simple building blocks. A central class of compounds are terpenes. More than 8000 terpenes and about 30,000 of the related terpenoids are currently known. They are the key substances for many biological and pharmaceutical functions.

18 Feb 2015

High-fat diet may reduce heart attack damage by 50%

It's well known that over the long run, a high-fat diet increases the risk of heart attack and stroke.

18 Feb 2015

Researchers identify molecule that can block progression of Alzheimer's disease

A molecule that can block the progress of Alzheimer's disease at a crucial stage in its development has been identified by researchers in a new study, raising the prospect that more such molecules may now be found.

18 Feb 2015

Trinity scientists reveal new marvel molecule that can block key process in inflammatory diseases

Scientists at Trinity College Dublin have uncovered a marvel molecule that blocks a key driver of inflammatory diseases. The finding could meet a major unmet clinical need by inspiring new non-invasive treatments for arthritis, multiple sclerosis and Muckle-Wells syndrome, among a myriad of other inflammatory diseases.

18 Feb 2015

Applying NMR to biological problems: an interview with Professor Arthur Palmer

Our current focus is on areas in protein folding, molecular recognition by proteins and also enzyme catalysis. NMR spin relaxation is one of the very powerful techniques in NMR for studying conformational dynamics in proteins or chemical kinetic processes.

From Bruker BioSpin Group 17 Feb 2015

TNF signaling molecule triggers Crohn's disease, ulcerative colitis

Cells lining the intestinal tract form a critical barrier, protecting our bodies from the billions of bacteria living in the gut. Breaches in this barrier are driven largely by a single signaling molecule called tumor necrosis factor (TNF), elevated amounts of which are associated with inflammatory bowel diseases like Crohn's disease and ulcerative colitis.

17 Feb 2015

Researchers identify molecule that plays key role in aggressive thyroid cancer, other cancers

Cancer researchers at Mayo Clinic's campus in Jacksonville, Florida, have identified a molecule they say is important to survival of anaplastic thyroid carcinoma (ATC) — a lethal tumor with no effective therapies.

17 Feb 2015

USPTO issues Notice of Allowance to Can-Fite BioPharma for psoriasis patent

Can-Fite BioPharma Ltd., a biotechnology company with a pipeline of proprietary small molecule drugs that are being developed to treat inflammatory diseases, cancer and sexual dysfunction, announced today that it has received a Notice of Allowance from the U.S. Patent and Trademark Office for CF101 in the treatment of psoriasis.

17 Feb 2015

Short-term, high-fat diet may reduce heart attack damage, shows study

It's well known that over the long run, a high-fat diet increases the risk of heart attack and stroke.

17 Feb 2015

New study finds promising target for future therapies to treat breast and ovarian cancer patients

The Food and Drug Administration's recent approval of the drug olaparib for ovarian cancer patients with inherited mutations in the genes BRCA1 or BRCA2 came as welcome news to the thousands of women now eligible to receive it. A new study by Dana-Farber Cancer Institute scientists indicates that the pool of patients who can benefit from the drug is potentially much wider - and offers a ready means of identifying them.

16 Feb 2015

KU Leuven researchers find aggressive form of HIV in Cuba

Engaging in unprotected sex with multiple partners increases the risk of contracting multiple strains of HIV, the virus that causes AIDS. Once inside a host, these strains can recombine into a new variant of the virus. One such recombinant variant observed in patients in Cuba appears to be much more aggressive than other known forms of HIV.

16 Feb 2015

Techimmuna may help diagnose rheumatoid arthritis

NCBJ POLATOM Radioisotope Centre has just introduced a new product to the nuclear medicine preparations market. Techimmuna will help to diagnose various cases of inflammation, in particular rheumatoid arthritis.

16 Feb 2015

Research finding could lead to new therapeutic target for treating hypertension in males

Higher levels of a "danger" molecule may be one reason males tend to become hypertensive earlier and more severely than females, scientists say.

16 Feb 2015

Researchers develop novel strategy in fight against cancer

A team of researchers led by Associate Professor Caroline Lee from the Yong Loo Lin School of Medicine at the National University of Singapore, in collaboration with Associate Professor Song Jianxing of the Department of Biological Sciences at the NUS Faculty of Science, has developed a novel strategy in the fight against cancer.

15 Feb 2015

Diabetes medication can help white blood cells fight bacterial infections

Pioglitazone, a medication approved for treatment of type 2 diabetes, can help bypass genetic defects in chronic granulomatous disease to help white blood cells fight bacterial infections, according to researchers at National Jewish Health.

12 Feb 2015

ADDF, Pfizer's CTI collaborate to advance development of new drugs for Alzheimer's disease

The Alzheimer's Drug Discovery Foundation and Pfizer's Centers for Therapeutic Innovation announced today a collaboration designed to advance the development of new small-molecule drugs for Alzheimer's disease and related dementias. As part of the first-of-its kind collaboration in Alzheimer's, the ADDF and CTI will jointly invest in translational research projects, with a focus on novel Alzheimer's drug targets.

11 Feb 2015

Virginia Tech purchases two Bruker fluorescence microscope solutions

The Vutara 350 can break the optical diffraction limit by an order of magnitude, opening up a myriad of research opportunities in single-molecule cellular processes.

From Bruker 11 Feb 2015

First human clinical study of ChromaDex's NIAGEN nicotinamide riboside meets primary endpoint

ChromaDex Corp. announced today that the initial results of the first human clinical study for the company's NIAGEN nicotinamide riboside (NR) has met its primary endpoint.

11 Feb 2015

Molecule News and Research

Lupus Research Institute announces this year's Novel Research Grants

Researchers show importance of DNA damage in fine tuning of innate immune system

From the scent of geranium to cough medicine; A self-assembling catalyst helps to construct complex biological scaffolds

High-fat diet may reduce heart attack damage by 50%

Researchers identify molecule that can block progression of Alzheimer's disease

Trinity scientists reveal new marvel molecule that can block key process in inflammatory diseases

Applying NMR to biological problems: an interview with Professor Arthur Palmer

TNF signaling molecule triggers Crohn's disease, ulcerative colitis

Researchers identify molecule that plays key role in aggressive thyroid cancer, other cancers

USPTO issues Notice of Allowance to Can-Fite BioPharma for psoriasis patent

Short-term, high-fat diet may reduce heart attack damage, shows study

New study finds promising target for future therapies to treat breast and ovarian cancer patients

KU Leuven researchers find aggressive form of HIV in Cuba

Techimmuna may help diagnose rheumatoid arthritis

Research finding could lead to new therapeutic target for treating hypertension in males

Researchers develop novel strategy in fight against cancer

Diabetes medication can help white blood cells fight bacterial infections

ADDF, Pfizer's CTI collaborate to advance development of new drugs for Alzheimer's disease

Virginia Tech purchases two Bruker fluorescence microscope solutions

First human clinical study of ChromaDex's NIAGEN nicotinamide riboside meets primary endpoint

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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