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New compound with antibacterial activity shows promising results within one hour in laboratory trials

Resistance to antibiotics is a problem that alarms the medical and scientific community. Bacteria resistant to three different classes of antibiotics, known as multi-drug resistant (MDR) bacteria, are far from rare.

15 May 2023

Study shows two distinct types of cerebellar neurons differentially regulate motor and social behaviors

The cerebellum, a major part of the hindbrain in all vertebrates, is important for motor coordination, language acquisition, and regulating social and emotional behaviors.

15 May 2023

Study reveals how serotonin affects animal behavior at the whole-brain scale

Because serotonin is one of the primary chemicals the brain uses to influence mood and behavior, it is also the most common target of psychiatric drugs.

15 May 2023

Phase 1 clinical trial of CAR-NKT cell therapy shows promising results in neuroblastoma patients

Researchers at Baylor College of Medicine/Texas Children's Cancer Center and collaborating institutions report interim results from a first-in-human phase 1 clinical trial evaluating the safety, antitumor activity and immunological characteristics of a genetically engineered natural killer T (NKT) cell immunotherapy for neuroblastoma, a childhood tumor that most commonly arises in the adrenal gland.

15 May 2023

Newly identified genetic variant provides protection from Alzheimer's disease

A single patient can spark new research questions and provide answers about a disease. And when a new case is identified, investigators can make connections between them that can lead to even more powerful and persuasive ideas about cause and treatment.

15 May 2023

Combination approach is safe, improves survival outcomes in a subset of glioblastoma patients

Intratumoral delivery of an engineered oncolytic virus (DNX-2401) targeting glioblastoma (GBM) cells combined with subsequent immunotherapy was safe and improved survival outcomes in a subset of patients with recurrent GBM, according to results from a multi-institutional Phase I/II clinical trial co-led by researchers at The University of Texas MD Anderson Cancer Center and the University of Toronto.

15 May 2023

Study offers new insights into how toxic proteins spread in the brains of people with Alzheimer's disease

Fresh insights into the spread of damaging proteins that build up in the brains of people with Alzheimer's disease could hold the key to stopping the condition progressing, a study says.

15 May 2023

Metabolically healthy and unhealthy 'forms' of obesity linked with increased risk of obesity-related cancers

New research to be presented at this coming week's European Congress on Obesity in Dublin, Ireland (17-20 May) and published in the Journal of the National Cancer Institute shows that both the metabolically healthy and unhealthy 'forms' of obesity are associated with an increased risk of various obesity-related cancers, with the relationship stronger in metabolically unhealthy obesity.

15 May 2023

Study sheds light on the importance of a subset of microglial cells in cognition and memory

A new study sheds light on the importance of microglia, the immune cells of the brain, in cognition and memory.

15 May 2023

Exploiting platelets for antitumor drug delivery and immune modulation of tumor microenvironment

Announcing a new publication for Acta Materia Medica journal. Platelets are blood components traditionally believed to have fundamental roles in vascular hemostasis and thrombosis.

15 May 2023

Brain cancer cells communicate with astrocytes to enhance tumor growth by energy transfer

Malignant brain tumors belong to a group of cancers with bleak prognosis. These tumors are resistant to treatment and considered incurable.

15 May 2023

Humanized mouse model for rare genetic disease developed for the first time

Mice with a defected human gene responsible for a rare genetic disease, called congenital adrenal hyperplasia, have been developed for the first time.

15 May 2023

Nanoparticles take aim at COVID-19 with lysosome-targeted delivery

Researchers discuss the use of endo-lysosome-targeted nanoparticles for delivering antiviral therapy to treat coronavirus infections.

15 May 2023

SARS-CoV-2 variants show altered glycan processing

Researchers examine spike-protein trimers from SARS-CoV-2 variants to compare the N (asparagine)-glycan landscape.

15 May 2023

Deep generative models to generate hypothetical SARS-CoV-2 spike sequences

Scientists explore the use of deep generative models in producing complete instances of as-yet undiscovered SARS-CoV2 Spike protein sequences. The resulting models substantially outperform a state-of-the-art generative model for protein sequences finetuned on SARS-CoV2 data.

14 May 2023

Swiss researchers identify plastic-degrading microbial strains in the Alps and Arctic region

Finding, cultivating, and bioengineering organisms that can digest plastic not only aids in the removal of pollution, but is now also big business.

13 May 2023

Drug combination can prolong survival and improve quality of life in patients with advanced lung cancer

A recent clinical trial showed that the drug combination of cemiplimab plus platinum chemotherapy can prolong survival in patients with advanced lung cancer when compared with placebo plus platinum chemotherapy. Now an analysis published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society, indicates that cemiplimab plus platinum chemotherapy also affects quality of life compared to chemotherapy alone.

13 May 2023

B Cell News and Research

New compound with antibacterial activity shows promising results within one hour in laboratory trials

Study shows two distinct types of cerebellar neurons differentially regulate motor and social behaviors

Study reveals how serotonin affects animal behavior at the whole-brain scale

Phase 1 clinical trial of CAR-NKT cell therapy shows promising results in neuroblastoma patients

Newly identified genetic variant provides protection from Alzheimer's disease

Combination approach is safe, improves survival outcomes in a subset of glioblastoma patients

Study offers new insights into how toxic proteins spread in the brains of people with Alzheimer's disease

Metabolically healthy and unhealthy 'forms' of obesity linked with increased risk of obesity-related cancers

Study sheds light on the importance of a subset of microglial cells in cognition and memory

Exploiting platelets for antitumor drug delivery and immune modulation of tumor microenvironment

Brain cancer cells communicate with astrocytes to enhance tumor growth by energy transfer

Humanized mouse model for rare genetic disease developed for the first time

Nanoparticles take aim at COVID-19 with lysosome-targeted delivery

SARS-CoV-2 variants show altered glycan processing

Deep generative models to generate hypothetical SARS-CoV-2 spike sequences

Swiss researchers identify plastic-degrading microbial strains in the Alps and Arctic region

Drug combination can prolong survival and improve quality of life in patients with advanced lung cancer

Newly identified biomarker may predict NSCLC patients' treatment response to chemoimmunotherapy

Patient-derived head and neck cancer organoids could aid the discovery of novel therapies

Using an intracellular toolkit to map organelle bio-geography in stem cells

Using single B cell screening to boost antibody discovery eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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