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Beyond COVID-19: the potential future applications of mRNA vaccines

Researchers described the production, mechanisms, and potential applications of mRNA vaccines.

6 Jul 2022

Evaluation of antinucleocapsid antibody seropositivity following SARS-CoV-2 infection in vaccinated individuals

A new study assessed both placebo and vaccine recipients in the mRNA-1273 (Moderna) phase 3 clinical trial who were infected with SARS-CoV-2 during the blinded, placebo-controlled trial phase.

6 Jul 2022

Study finds flaviviruses can manipulate host skin microbiota to produce a scent that attracts mosquitoes

Researchers assessed the impact of mosquito-transmitted flaviviruses on host skin microbiota.

6 Jul 2022

New model reveals cancer-driving mutations

In this interview, News-Medical speaks to Maxwell Sherman, an MIT graduate student and one of the lead authors of a study that used a new method to investigate cancer genomes.

6 Jul 2022

"Selfish chromosomes" explain why most human embryos die very early on, study suggests

New research by a scientist at the Milner Center for Evolution at the University of Bath suggests that "selfish chromosomes" explain why most human embryos die very early on. The study, published in PLoS, Biology, explaining why fish embryos are fine but sadly humans' embryos often don't survive, has implications for the treatment of infertility.

6 Jul 2022

New atomic-level models of spike protein play a key role in COVID-19 infection and immunity

When the coronavirus causing COVID-19 infects human cells, the cell's protein-processing machinery makes modifications to the spike protein that render it more flexible and mobile, which could increase its ability to infect other cells and to evade antibodies, a new study from the University of Illinois Urbana-Champaign found.

6 Jul 2022

Bone marrow transplants may be an effective treatment for ALS, research suggests

Along with the central nervous system, the immune system may play a fundamental role in Amyotrophic Lateral Sclerosis (ALS), suggesting that bone marrow transplants may be an effective novel treatment for the neurodegenerative disease.

6 Jul 2022

Paxlovid resistance associated with SARS-CoV-2 3CLpro mutations

In a recent study published in the bioRxiv* preprint server, researchers at the Medical University of Innsbruck assessed the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 3CLpro mutations responsible for Paxlovid resistance. The 3-chymotrypsin-like protease (3CLPro), or main protease (Mpro), is the main protease found in coronaviruses.

6 Jul 2022

Healthy, cancer, and immunosuppressed patients all benefit from COVID boosters

In a recent study posted to the medRxiv* pre-print server, researchers developed a mechanistic mathematical model to predict the course of vaccine-induced immunity in healthy and immunosuppressed patients for the long term, exceeding the time frames for which clinical data is currently available.

5 Jul 2022

Novel inhalable COVID-19 vaccine

A recent study published in the Nature Biomedical Engineering journal illustrated a novel inhalable SARS-CoV-2 vaccine candidate centered on exosomes (Exos) coupled with recombinant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor-binding domain (RBD).

5 Jul 2022

Scientists uncover HIV’s sweet spot

HIV researchers have long been trying to identify the specific cells that the virus prefers to infect and hide in. They know that HIV favors a special type of immune cells called memory CD4 T cells.

5 Jul 2022

Immune response triggered by COVID-19 damages the brain's blood vessels to cause neurological complications

A study from the National Institutes of Health describes the immune response triggered by COVID-19 infection that damages the brain's blood vessels and may lead to short- and long-term neurological symptoms.

5 Jul 2022

Researchers explore how diet and feeding patterns affect intestinal microbes

An estimated 500 to 1,000 bacterial species reside in each person's gut, perhaps numbering 100,000 trillion microorganisms.

5 Jul 2022

Research uses big data to find cancerous mutations in cells

Artificial intelligence and machine learning are among the latest tools being used by cancer researchers to aid in detection and treatment of the disease.

5 Jul 2022

Study opens up a new avenue for the development of selective drug therapies

Researchers at the Department of Energy's Oak Ridge National Laboratory have definitively linked the function of a specific domain of proteins important in plant-microbe biology to a cancer trigger in humans, knowledge that had eluded scientists for decades.

5 Jul 2022

Synthetic molecule Pep19 helps regulate and balance key metabolic functions, study shows

A study conducted at the University of São Paulo in Brazil shows that the synthetic molecule Pep19 acts on the endocannabinoid system, which helps regulate and balance key metabolic functions, such as appetite, fat breakdown (lipolysis), and energy release.

5 Jul 2022

Protein C News and Research

Beyond COVID-19: the potential future applications of mRNA vaccines

Evaluation of antinucleocapsid antibody seropositivity following SARS-CoV-2 infection in vaccinated individuals

Study finds flaviviruses can manipulate host skin microbiota to produce a scent that attracts mosquitoes

New model reveals cancer-driving mutations

"Selfish chromosomes" explain why most human embryos die very early on, study suggests

New atomic-level models of spike protein play a key role in COVID-19 infection and immunity

Bone marrow transplants may be an effective treatment for ALS, research suggests

Paxlovid resistance associated with SARS-CoV-2 3CLpro mutations

Healthy, cancer, and immunosuppressed patients all benefit from COVID boosters

Novel inhalable COVID-19 vaccine

Scientists uncover HIV’s sweet spot

Immune response triggered by COVID-19 damages the brain's blood vessels to cause neurological complications

Researchers explore how diet and feeding patterns affect intestinal microbes

Research uses big data to find cancerous mutations in cells

Study opens up a new avenue for the development of selective drug therapies

Synthetic molecule Pep19 helps regulate and balance key metabolic functions, study shows

Study identifies a molecule that boosts fat burning

Novel oral nano-in-micro system provides efficient curcumin delivery to alleviate ulcerative colitis

Human gingival epithelial cells become damaged by cannabis smoke condensate

Next-generation SARS-CoV-2 nucleocapsid-based vaccines may provide optimal protection against infection

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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