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Genetic influence on immune system appears to be higher than previously thought

Nearly three quarters of immune traits are influenced by genes, new research from King's College London reveals.

5 Jan 2017

Study provides new insights into molecular subtypes of esophageal cancer

A comprehensive analysis of 559 esophageal and gastric cancer samples, collected from patients around the world, suggests the two main types of esophageal cancer differ markedly in their molecular characteristics and should be considered separate diseases.

5 Jan 2017

Researchers develop first sensor that can identify IBD and distinguish between two subtypes

Researchers have developed the first sensor capable of objectively identifying inflammatory bowel disease (IBD) and distinguishing between its two subtypes.

4 Jan 2017

BUSM professor receives Ellison Foundation grant to explore new Parkinson's disease target

Richard Myers, PhD, professor of neurology at Boston University School of Medicine, was recently awarded $100,000 from the Ellison Foundation for research to further study a Parkinson's disease (PD) target.

4 Jan 2017

Researchers develop first non-human primate X-SCID models using genome editing techniques

Researchers affiliated with the Kawasaki INnovation Gateway at SKYFRONT, have successfully generated the first ever non-human primate X-SCID models by using two genome editing techniques. The findings were published in Cell Stem Cell, July 2016.

3 Jan 2017

Genes influencing social communication skills linked to genes underlying psychiatric disorders

The researchers studied the genetic overlap between the risk of having these psychiatric disorders and measures of social communicative competence - the ability to socially engage with other people successfully - during middle childhood to adolescence.

3 Jan 2017

UM SOM study identifies key Zika proteins as likely suspects for damage

Until it burst onto the scene earlier this year, Zika was an obscure, little-known virus. As a result, scientists know little about how it works.

3 Jan 2017

Certain human gut bacteria may make new diets less effective

Your microbiota may not be on your side as you try improving your diet this New Year's. In a study published December 29 in Cell Host & Microbe, researchers explore why mice that switch from an unrestricted American diet to a healthy, calorie-restricted, plant-based diet don't have an immediate response to their new program.

30 Dec 2016

Fred Hutch’s new Evergreen Fund to promote commercialization of research into lifesaving therapies

Fred Hutchinson Cancer Research Center announced its first-ever grants from its newly established Evergreen Fund to spur researchers' efforts to advance bold ideas toward creating or partnering with a commercial entity.

28 Dec 2016

New research points to lncRNA's key role in helping control cellular processes

Scientific research over the past decade has concentrated almost exclusively on the 2 percent of the genome's protein coding regions, virtually ignoring the other 98 percent, a vast universe of non-coding genetic material previously dismissed as nothing more than 'junk.'

27 Dec 2016

Genomic sequencing reveals new insights into major shigellosis outbreaks in California

In a study that could have significant impact on how disease outbreaks are managed, researchers at UC Davis and the California Department of Public Health have sequenced and analyzed genomes from Shigella sonnei (S. sonnei) bacteria associated with major shigellosis outbreaks in California in 2014 and 2015.

23 Dec 2016

Linking human genome sequences to EHR information could influence clinical medicine, says expert

The value of intersecting the sequencing of individuals' exomes or full genomes to find rare genetic variants -- on a large scale -- with their detailed electronic health record information has "myriad benefits, including the illumination of basic human biology, the early identification of preventable and treatable illnesses, and the identification and validation of new therapeutic targets," wrote Daniel J. Rader, MD, chair of the Department of Genetics, in the Perelman School of Medicine at the University of Pennsylvania, in Science this week, with Scott M. Damrauer, MD, an assistant professor of Surgery at Penn and the Veterans Affairs Medical Center in Philadelphia.

23 Dec 2016

UC researchers uncover obesity-related protein's role in leukemia development

Cancer researchers at the University of Cincinnati College of Medicine have found an obesity-associated protein's role in leukemia development and drug response which could lead to more effective therapies for the illness.

22 Dec 2016

Scientists discover OGDHL and NRD1 genes linked to progressive loss of neurological function

An international team of scientists has discovered that the gene, OGDHL, a key protein required for normal function of the mitochondria -- the energy-producing factory of the cell -- and its chaperone, nardilysin (NRD1) are linked to progressive loss of neurological function in humans.

22 Dec 2016

Scientists identify gene variants causing unrecognized developmental disorder

An international team of scientists has identified variants of the gene EBF3 causing a developmental disorder with features in common with autism.

22 Dec 2016

New computational tool can predict personal cancer driver genes to optimize treatment

Columbia University Medical Center researchers have created a computational tool that can rapidly predict which genes are implicated in an individual's cancer and recommend treatments.

22 Dec 2016

High BMI leads to epigenetic changes, study shows

The extra pounds you gain during the holidays will not only show up on your hips but will also affect your DNA.

22 Dec 2016

TSRI scientists identify microbial natural products as abundant sources of potent anticancer drugs

Scientists from the Florida campus of The Scripps Research Institute have developed an efficient process to rapidly discover new “enediyne natural products” from soil microbes that could be further developed into extremely potent anticancer drugs.

22 Dec 2016

Mount Sinai researchers laying groundwork to find effective treatment for Zika virus

Researchers at the Icahn School of Medicine at Mount Sinai are working on the basic science that lays the groundwork to finding a way to treat and prevent the Zika virus, a global health risk.

22 Dec 2016

Researchers find accumulation of tumor suppressor in liver after food withdrawal

Tumor suppressors stop healthy cells from becoming cancerous. Researchers from Charité - Universitätsmedizin Berlin, the Medical University of Graz and the German Institute of Human Nutrition in Potsdam-Rehbruecke have found that p53, one of the most important tumor suppressors, accumulates in liver after food withdrawal.

21 Dec 2016

Genome News and Research

Genetic influence on immune system appears to be higher than previously thought

Study provides new insights into molecular subtypes of esophageal cancer

Researchers develop first sensor that can identify IBD and distinguish between two subtypes

BUSM professor receives Ellison Foundation grant to explore new Parkinson's disease target

Researchers develop first non-human primate X-SCID models using genome editing techniques

Genes influencing social communication skills linked to genes underlying psychiatric disorders

UM SOM study identifies key Zika proteins as likely suspects for damage

Certain human gut bacteria may make new diets less effective

Fred Hutch’s new Evergreen Fund to promote commercialization of research into lifesaving therapies

New research points to lncRNA's key role in helping control cellular processes

Genomic sequencing reveals new insights into major shigellosis outbreaks in California

Linking human genome sequences to EHR information could influence clinical medicine, says expert

UC researchers uncover obesity-related protein's role in leukemia development

Scientists discover OGDHL and NRD1 genes linked to progressive loss of neurological function

Scientists identify gene variants causing unrecognized developmental disorder

New computational tool can predict personal cancer driver genes to optimize treatment

High BMI leads to epigenetic changes, study shows

TSRI scientists identify microbial natural products as abundant sources of potent anticancer drugs

Mount Sinai researchers laying groundwork to find effective treatment for Zika virus

Researchers find accumulation of tumor suppressor in liver after food withdrawal

The art of CRISPR: The power and promise of gene editing eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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