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Analysis of antioxidants, stress markers in the blood could lead to new diagnostic tool for breast cancer

A new study that analyzes levels of antioxidants and stress markers in the blood could lead to a new diagnostic tool for breast cancer. The research will be presented this week in Philadelphia at the American Physiological Society's annual meeting at Experimental Biology 2022.

2 Apr 2022

Study explores molecular mechanisms underlying SARS-CoV-2 infection of macrophages and the induction of pro-inflammatory cytokines

Researchers examined the role of sialic acid-binding immunoglobulin-type lectins-1, a myeloid cell-specific receptor, in facilitating SARS-CoV-2 infection of ACE2-deficient macrophages and its effect on pro-inflammatory cytokine expression.

1 Apr 2022

Study determines the molecular signatures of monocytes and regulatory T cells in the circulating blood of COVID-19 patients

Researchers examined the unique clusters of monocytes and regulatory T cells in the circulating blood from convalescent COVID-19 patients over a prolonged period after recovery, using scRNA sequencing.

31 Mar 2022

Messenger ribonucleic acid boosters shown to be effective against Omicron infections in mice

Researchers evaluated the protection conferred by booster doses of the preclinical version of the Moderna mRNA-1273 vaccine and a SARS-CoV-2 Omicron variant-matched vaccine against Omicron infections in mice.

31 Mar 2022

Study sheds light on biomechanistic reasons why allergic asthma correlates with milder forms of COVID-19

An exciting study recently published in the PNAS underscores the role of a well-established cytokine IL-13 in protecting our cells against SARS-CoV-2.

31 Mar 2022

Role of SARS-CoV-2 S1 subunit in severe COVID-19

A new study aimed to determine whether portions of the SARS-CoV-2 spike protein are capable of activating innate immune cells like Gal-3.

30 Mar 2022

Researchers discover potential link between inflammation and structure of specific brain regions

A potential link between inflammation and the structure of specific regions of the brain has been identified by researchers at the University of Birmingham.

30 Mar 2022

Preclinical investigation of intranasal adjuvanted COVID-19 vaccine

A new study reported systemic and mucosal immunity against SARS-CoV-2 via intranasal delivery of a vaccine containing recombinant SARS-CoV-2 antigens, nucleocapsid, and spike subunit.

30 Mar 2022

Results of Phase 3 Nanocovax SARS-CoV-2 vaccine trial suggest robust effectiveness

A new study presented the findings of the Phase 3 trial of the Nanocovax coronavirus disease 2019 (COVID-19) vaccine.

29 Mar 2022

Durability and functionality of the humoral and T-cell response to SARS-CoV-2 and its variants in recovered patients

A recent study investigated the potency and functionality of T-cell and humoral responses against the SARS-CoV-2 wild-type strain and its variants.

28 Mar 2022

Tuberculosis infection protects mice against COVID-19

To study if prior Mtb infection affects the response to CoV2 infection, K18-hACE2 (ACE2) and C57BL/6 (B6) mice were infected with Mtb, and post thirty days, were exposed to CoV2.

27 Mar 2022

Study evaluates efficacy of sarilumab in severe/critical COVID-19 patients

Researchers discuss the results of a clinical trial to assess the efficacy and safety of IV sarilumab for the treatment of hospitalized COVID-19 patients.

27 Mar 2022

Study explores macrophage susceptibility to SARS-CoV-2 virions

A new study investigated the susceptibility of macrophages to SARS-CoV-2 virions.

25 Mar 2022

Researchers investigate Galectin-9 as a new treatment target for COVID-19

Researchers discuss alternate therapeutic targets for treating COVID-19 and the effects of Gal-9 on SARS-CoV-2 infection and the immune response.

23 Mar 2022

Monoclonal antibodies found to prevent lung inflammation in SARS-CoV-2-Omicron-infected mice

Researchers investigated how monoclonal antibodies, S309 and AZD7442, reduced lung infection in mice infected with the SARS-CoV-2 new variant of concern Omicron's BA.1, BA.1.1, and BA.2 sublineages.

23 Mar 2022

The effect of SARS-CoV-2 on the expression of CD48 in the lungs and in the peripheral blood of COVID-19 patients

Researchers performed an in situ analysis to evaluate the correlation between CD48 expression and COVID-19.

22 Mar 2022

IU researchers exploring new ways to treat seasonal or intermittent asthma

Researchers from Indiana University School of Medicine Department of Microbiology and Immunology are studying new ways to treat seasonal or intermittent asthma.

21 Mar 2022

Glycogen synthase kinase-3 inhibitors found to attenuate COVID-19-associated cytokine storm

In a new study, researchers investigated whether the SARS-CoV-2 spike protein and its S2 subunit induced the expression of C–X–C motif chemokine 10, a subset of cytokine.

21 Mar 2022

Biological timeline of COVID-19 immune recovery described in new research

In a recent study published on the bioRxiv* preprint server, a group of researchers from the University of California, San Francisco, looked at intra-patient immunological changes over time to see if there were any changes in immune responses associated with successful COVID-19 resolution.

21 Mar 2022

Substantial alteration in gut microbiome observed in children with with MIS-C and COVID

A team of scientists from Turkey has recently evaluated the diversity and composition of gut microbiota in children diagnosed with multisystem inflammatory syndrome (MIS-C) and acute coronavirus disease 2019 (COVID-19). They have observed significant alteration in the gut microbiota composition in children with MIS-C. These changes are associated with autoimmunity, metabolic dysfunction, and obesity.

21 Mar 2022

Interleukin 3 News and Research

Analysis of antioxidants, stress markers in the blood could lead to new diagnostic tool for breast cancer

Study explores molecular mechanisms underlying SARS-CoV-2 infection of macrophages and the induction of pro-inflammatory cytokines

Study determines the molecular signatures of monocytes and regulatory T cells in the circulating blood of COVID-19 patients

Messenger ribonucleic acid boosters shown to be effective against Omicron infections in mice

Study sheds light on biomechanistic reasons why allergic asthma correlates with milder forms of COVID-19

Role of SARS-CoV-2 S1 subunit in severe COVID-19

Researchers discover potential link between inflammation and structure of specific brain regions

Preclinical investigation of intranasal adjuvanted COVID-19 vaccine

Results of Phase 3 Nanocovax SARS-CoV-2 vaccine trial suggest robust effectiveness

Durability and functionality of the humoral and T-cell response to SARS-CoV-2 and its variants in recovered patients

Tuberculosis infection protects mice against COVID-19

Study evaluates efficacy of sarilumab in severe/critical COVID-19 patients

Study explores macrophage susceptibility to SARS-CoV-2 virions

Researchers investigate Galectin-9 as a new treatment target for COVID-19

Monoclonal antibodies found to prevent lung inflammation in SARS-CoV-2-Omicron-infected mice

The effect of SARS-CoV-2 on the expression of CD48 in the lungs and in the peripheral blood of COVID-19 patients

IU researchers exploring new ways to treat seasonal or intermittent asthma

Glycogen synthase kinase-3 inhibitors found to attenuate COVID-19-associated cytokine storm

Biological timeline of COVID-19 immune recovery described in new research

Substantial alteration in gut microbiome observed in children with with MIS-C and COVID

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