Microarray News and Research

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FDA go ahead for first of kind genetic lab test

The U.S. Food and Drug Administration (FDA) has approved the marketing of the first laboratory test system that will allow physicians to consider unique genetic information from patients in selecting medications and doses of medications for a wide variety of common conditions such as cardiac disease, psychiatric disease, and cancer.

27 Dec 2004

New cancer detection technology from Rubicon Genomics

Rubicon Genomics has invented a more effective technology for the diagnosis and prognosis of cancer compared to what hospitals and reference laboratories use today. MethylPlex™ is the most sensitive method in use to detect the patterns of abnormal DNA methylation arising in the serum and urine of patients during tumor formation and progression.

14 Dec 2004

New technology will advance our understanding of role of complex sugar chains decorating the surface of cells in the body

An international consortium of scientists lead by Dr. James Paulson of The Scripps Research Institute has created a technology that will advance our understanding of the role of complex sugar chains (glycans or carbohydrates) that decorate the surface of cells in the body.

8 Dec 2004

New and revealing portrait of Yersinia pestis emerges

Yersinia pestis, the causative agent of the “Black Death” or “Bubonic” plague, has been a scourge of human civilization. One of the most virulent bacterial pathogens known, killing nearly 90% of those infected, Y. pestis was responsible for three historic pandemics that shattered whole societies.

4 Dec 2004

Discovery of a new cancer gene, which, when damaged, may promote prostate cancer

Together with an international research team, researchers from VTT Technical Research Centre of Finland have developed an effective method for the screening and identification of genes that under normal conditions suppress cancer growth.

24 Nov 2004

New genetic test has proven useful as a prognostic tool for ovarian cancer

The identification of a gene expression profile using microarray technology may help clinicians better determine the prognosis of patients with advanced stage ovarian cancer and may eventually help provide targeted therapies for this hard-to-treat disease, according to a study led by investigators at Beth Israel Deaconess Medical Center (BIDMC).

18 Nov 2004

Research aims to understand how genetic information translates into biological activity

The National Institute of Standards and Technology (NIST) has launched a new $6.25 million, five-year program to explore and address challenges in measurement, validation and quality control for the rapidly growing field of gene expression profiling.

11 Nov 2004

Nanogen announces clinical diagnostic to simultaneously detect multiple respiratory viruses

Nanogen announced today that it is developing new analyte specific reagents (ASRs) for clinical reference laboratories to develop and validate a single test to detect six of the most common respiratory viruses.

10 Nov 2004

Micro-array technology is revolutionising current drug development

Gene expression micro-array technology is benefiting all phases of the discovery, development and subsequent use of new cancer therapeutics

29 Oct 2004

New radiotherapy regime benefits young women with breast cancer

Women under 35 years of age with breast cancer can have an almost 20% lower risk of their disease recurring if they are treated using a new radiotherapy regime.

26 Oct 2004

Study could lead to new, more effective treatments for urinary tract infections

Anyone who thinks scientists lead a glamorous, exciting life should talk to Jennifer Snyder, a graduate student at the University of Maryland’s School of Medicine.

25 Oct 2004

New study offers rare glimpse of how the smallpox virus attacks its victims

Results of a new study in monkeys offer scientists a rare glimpse of how, on a molecular level, the smallpox virus attacks its victims. The findings shed light on how the virus caused mass death and suffering, and will help point the way to new diagnostics, vaccines and drugs that would be needed in the event of a smallpox bioterror incident.

12 Oct 2004

Researchers have found a starting point to establishing the genetic basis for sinus disease

In a three-year analysis of more than 10,500 genes, one-third of the human genome, researchers at Johns Hopkins have found a starting point to establishing the genetic basis for sinus disease and the growth of nasal polyps, illnesses not well understood despite their prevalence.

8 Oct 2004

University of Florida researchers reveal secret lives of genes during spinal injury

The body attempts to heal a damaged spinal cord in much the same way it repairs skin after simple cuts and scrapes, an insight that may lead to new treatments for the thousands of people paralyzed each year because of spinal cord injuries, say scientists at the University of Florida Health Science Center.

5 Oct 2004

Artificial neural networks and DNA microarrays to successfully predict clinical outcomes of neuroblastoma patients

Researchers at the National Cancer Institute (NCI), have used artificial neural networks (ANNs) and DNA microarrays to successfully predict the clinical outcome of patients diagnosed with neuroblastoma (NB).

4 Oct 2004

Two types of thyroid cancer can be readily identified by differences in only a few genes

Two types of thyroid cancer that are closely related and sometimes difficult to distinguish can be readily identified by differences in only a few genes, new research shows.

29 Sep 2004

Clusters of genes within human aortas appear to predict risk for atherosclerosis

Duke University Medical Center researchers have identified specific clusters of genes within human aortas that appear to predict with great specificity which patients may be at highest risk for developing atherosclerosis, as well as the severity of the disease.

28 Sep 2004

Hair growing stem cells may one day provide treatments for human hair conditions

Researchers at the Howard Hughes Medical Institute at The Rockefeller University have isolated stem cells from the skin of a mouse, and showed, for the first time, that an individual stem cell can renew itself in the laboratory and then be used in grafts to produce skin, hair and oil glands.

5 Sep 2004

Researchers have identified multiple changes in the gene-expression patterns of cells involved with tumor progression in liver cancer patients

Virginia Commonwealth University researchers have identified multiple changes in the gene-expression patterns of cells involved with tumor progression in liver cancer patients and in those with cirrhosis, which may help scientists predict a person’s risk of developing primary liver cancer.

25 Aug 2004

Scientists lead fight against blood cancers

The Leukaemia Research Fund has awarded £140,000 to three teams working within the Nuffield Department of Clinical Laboratory Sciences to find and improve treatments for leukaemia and related blood cancers.

7 Aug 2004