Mitochondria News and Research

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Scientists gain atomic-level insight into behavior of a protein that promotes cancer growth

The neutron reflexometry method has given scientists an atomic-level insight into the behavior of Bcl-2, a protein that promotes cancerous cell growth. The new study was carried out by Umeå chemists in collaboration with the research facilities ESS and ISIS and is published in Nature Communications Biology.

28 Apr 2021

Researchers identify potential therapeutic target to prevent neurodegeneration after a stroke

Researchers with the Peter O'Donnell Jr. Brain Institute at UT Southwestern have identified a new protein implicated in cell death that provides a potential therapeutic target that could prevent or delay the progress of neurodegenerative diseases following a stroke.

27 Apr 2021

CU Cancer Center researchers receive PRCRP grant to investigate metastasis

Two members of the University of Colorado Cancer Center have received prestigious Idea Awards from the U.S. Department of Defense's Peer Reviewed Cancer Research Program.

27 Apr 2021

Survivors and non-survivors of critical illness show differences in cell adaptation to adverse conditions

Creating the best conditions for cells to make energy and survive critical illness is a challenge little understood in modern medicine.

26 Apr 2021

Researchers discover molecule that provides dual protection against vascular inflammation

A multidisciplinary team of researchers from Duke-NUS Medical School and the Agency for Science, Technology and Research (A*STAR) in Singapore discovered a new mitochondrial peptide called MOCCI that plays an important role in regulating inflammation of blood vessel and immunity.

22 Apr 2021

Researchers identify the cause of severe canine juvenile epilepsy

In a study conducted at the University of Helsinki, researchers found a cause for severe epilepsy resulting in death in Parson Russell Terrier puppies at a few months of age. A change in the PITRM1 gene can lead to a dysfunction of mitochondria, the cellular energy pumps.

21 Apr 2021

Researchers reveal a potential therapeutic strategy against T-cell acute lymphoblastic leukemia

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive type of leukemia in which too many T-cell lymphoblasts, or immature white blood cells, are found in the bone marrow and blood.

20 Apr 2021

Japanese–European scientists detect novel genetic mitochondrial disorder

The list of known genetic mitochondrial disorders is ever-growing, and ongoing research continues to identify new disorders in this category.

15 Apr 2021

Biology of single-celled organisms reveals potential treatment target for COPD

In a series of experiments that began with amoebas -- single-celled organisms that extend podlike appendages to move around -- Johns Hopkins Medicine scientists say they have identified a genetic pathway that could be activated to help sweep out mucus from the lungs of people with chronic obstructive pulmonary disease a widespread lung ailment.

13 Apr 2021

Gene therapy may offer a new approach to preserving vision in people with retinitis pigmentosa

A gene therapy protects eye cells in mice with a rare disorder that causes vision loss, especially when used in combination with other gene therapies, shows a study published today in eLife.

13 Apr 2021

Researchers receive $500,000 grant to test novel approach for restoring damaged muscles after injury

Researchers from the University of Tennessee Health Science Center have received a $500,000 grant over three years from the Department of Defense to test a novel strategy using mitochondria transplantation therapy for restoration of neuromuscular structure and function after injury.

12 Apr 2021

Obesity reduces mitochondrial gene expression in fat tissue, finds study

A twin study recently completed at the University of Helsinki indicates that the machinery responsible for energy handling in fat tissue is working poorly in obesity.

9 Apr 2021

Study shows Urolithin A as a potent enhancer of muscle function in mice with muscular dystrophy

Progression of Duchenne Muscle Dystrophy (DMD) can be delayed in mice by supplementing their diets with Urolithin A, according to new results reported today.

9 Apr 2021

Mitochondrial DNA mutations can reduce death risk in people with bowel cancer

Mutations in the DNA of the cell's energy 'factories' increases the chances of survival for people with bowel cancer, according to a study published today (Thursday) in Nature Metabolism.

9 Apr 2021

Parkinson's disease, type 2 diabetes, and cancer share the same pathway, shows study

When cells are stressed, chemical alarms go off, setting in motion a flurry of activity that protects the cell's most important players. During the rush, a protein called Parkin hurries to protect the mitochondria, the power stations that generate energy for the cell.

8 Apr 2021

Urolithin A shows promise to slow progression of Duchenne Muscle Dystrophy

Progression of Duchenne Muscle Dystrophy (DMD) can be delayed in mice by supplementing their diets with Urolithin A, according to new results reported today.

7 Apr 2021

Gut microbiome communicates with horse’s cells to enhance their athletic performance

A horse’s gut microbiome communicates with its host by sending chemical signals to its cells, which has the effect of helping the horse to extend its energy output, finds a new study published in Frontiers in Molecular Biosciences.

7 Apr 2021

$10.8 million grant from NIH helps establish Arkansas Integrative Metabolic Research Center

A $10.8 million grant from the National Institutes of Health will enable an interdisciplinary team of researchers at the University of Arkansas and University of Arkansas for Medical Sciences to address the role of cell and tissue metabolism in rare and common diseases such as cancer, diabetes, obesity and mitochondrial disorders.

6 Apr 2021

Researchers reveal novel therapeutic target in the treatment of certain cancers

Mount Sinai Researchers Find "Removal of AKAP11 Protein by Autophagy as a key to Fuel Mitochondrial Metabolism and Tumor Cell Growth through activating protein kinase A (PKA) (Patent pending)"

1 Apr 2021

Soft X-ray microscopy shows how viral pathogens penetrate human cells

How do viral pathogens succeed in penetrating human cells? Which cellular mechanisms do they use to multiply efficiently and, in doing so, how do they change the structure of their host cell? These questions are the focus of a pan-European research project called "Compact Cell-Imaging Device" (CoCID), in which Heidelberg scientists are playing a major role.

31 Mar 2021

Mitochondria News and Research

Scientists gain atomic-level insight into behavior of a protein that promotes cancer growth

Researchers identify potential therapeutic target to prevent neurodegeneration after a stroke

CU Cancer Center researchers receive PRCRP grant to investigate metastasis

Survivors and non-survivors of critical illness show differences in cell adaptation to adverse conditions

Researchers discover molecule that provides dual protection against vascular inflammation

Researchers identify the cause of severe canine juvenile epilepsy

Researchers reveal a potential therapeutic strategy against T-cell acute lymphoblastic leukemia

Japanese–European scientists detect novel genetic mitochondrial disorder

Biology of single-celled organisms reveals potential treatment target for COPD

Gene therapy may offer a new approach to preserving vision in people with retinitis pigmentosa

Researchers receive $500,000 grant to test novel approach for restoring damaged muscles after injury

Obesity reduces mitochondrial gene expression in fat tissue, finds study

Study shows Urolithin A as a potent enhancer of muscle function in mice with muscular dystrophy

Mitochondrial DNA mutations can reduce death risk in people with bowel cancer

Parkinson's disease, type 2 diabetes, and cancer share the same pathway, shows study

Urolithin A shows promise to slow progression of Duchenne Muscle Dystrophy

Gut microbiome communicates with horse’s cells to enhance their athletic performance

$10.8 million grant from NIH helps establish Arkansas Integrative Metabolic Research Center

Researchers reveal novel therapeutic target in the treatment of certain cancers

Soft X-ray microscopy shows how viral pathogens penetrate human cells

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