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New hybrid molecule uses Trojan horse approach to treat obesity

A team led by metabolism researcher Prof Timo D. Müller at Helmholtz Munich has developed a new approach for treating obesity and type 2 diabetes: a hybrid molecule uses the well-known GLP-1/GIP signalling pathway as a "door opener" and delivers an additional metabolic modulator specifically into the target cells.

29 Apr 2026

Eating creates temporary metabolic state that boosts T cell function

Diets and healthy eating habits hold promise for preventing and treating diseases, but far less is known about acute effects to the immune system shortly after a meal.

29 Apr 2026

New map reveals B cell clusters linked to faster diabetic kidney disease

A detailed new map of the human kidney revealed a previously unrecognized form of diabetic kidney disease (DKD) marked by clusters of immune cells-specifically B cells-that are linked to faster disease progression.

29 Apr 2026

Technique will turbocharge new medicines to combat antimicrobial resistance

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29 Apr 2026

Scientists redesign CAR-T cells to fight more than cancer

This review examines how CAR-T cell therapy is expanding beyond blood cancers into solid tumors, autoimmune diseases, chronic viral infections, and next-generation immune-cell platforms. It highlights promising engineering advances, including universal CAR-T cells, in vivo delivery, CAR-NK cells, and safety switches, while emphasizing unresolved challenges in durability, safety, scalability, and global access.

29 Apr 2026

Continuous flow porphyrin synthesis reveals new insights through real-time UV-Vis monitoring

New research from Professor Anna Slater and colleagues at the University of Liverpool demonstrates how continuous flow chemistry, combined with inline UV-Vis spectroscopy, can transform both the understanding and execution of porphyrin synthesis leading to improved yields in both quality and quantity.

From Asynt 29 Apr 2026

Study suggests a U-shaped link between cholesterol levels and mortality among Chinese adults

A new commentary published in Engineering highlights key findings from a large multinational cohort study that re-evaluates cholesterol management for cardiovascular and chronic disease prevention, suggesting a U-shaped association between cholesterol levels and mortality among Chinese adults that challenges the conventional "lower is better" approach.

28 Apr 2026

UIC researchers develop anti-cancer therapy inspired by bacteria in tumors

Researchers at the University of Illinois Chicago have developed an anti-cancer therapy inspired by bacteria found in cancer tumors.

28 Apr 2026

WHO report shows measurable progress in reducing global hepatitis infections

Global efforts to combat viral hepatitis are delivering measurable progress in reducing infections and deaths, but the disease remains a major global health challenge, according to a new World Health Organization (WHO) report released today at the World Hepatitis Summit.

28 Apr 2026

Experimental drug ZED1227 protects the whole body from gluten damage

An experimental drug may in future provide a new form of protection for people with celiac disease.

28 Apr 2026

Experts establish new clinical trial endpoints for oligometastatic cancer

An international group of experts led by the Comprehensive Cancer Centre (CCC) at MedUni Vienna and University Hospital Vienna has established endpoints for clinical trials in patients with cancer and isolated metastases.

28 Apr 2026

Engineered gut bacteria successfully treat metabolic drivers of liver disease

When the liver fails, toxins - such as ammonia - that should be filtered from the blood build up and reach the brain.

28 Apr 2026

New imaging method maps DNA replication forks with single-cell resolution

Researchers at The University of Texas MD Anderson Cancer Center have developed a new imaging method, known as RF-SIRF, that quantitatively detects and maps reversed DNA replication forks with single-cell resolution

28 Apr 2026

UBC researchers develop new way to target previously undruggable proteins

Researchers at the University of British Columbia and BC Cancer have developed a new way to target proteins long considered "undruggable," opening the door to new treatments for prostate cancer and other serious diseases.

28 Apr 2026

AI tool estimates biological age from photos to predict cancer outcomes

The Mass General Brigham research team behind FaceAge, an artificial intelligence (AI) tool that can estimate a person's biological age from a single photo, is reporting in a new study that estimating biological age from multiple photos taken over time can provide even more information about how well a person with cancer will do with treatment.

28 Apr 2026

Virginia Tech team identifies proteins that can reverse lung scarring

A Virginia Tech team has identified a promising new therapeutic strategy for idiopathic pulmonary fibrosis (IPF), showing that blocking two proteins can halt and even reverse lung scarring in pre-clinical models.

28 Apr 2026

New insights into predicting myeloma drug response

Although patients with the same cancer diagnosis may respond very differently to treatment, clinicians still have limited tools at their disposal to predict who is most likely to benefit or suffer from a particular myeloma therapy.

28 Apr 2026

New intervention improves coping and well-being in young cancer patients

A cancer diagnosis can upend any life. For young adults already navigating a step into independence, it can be especially distressing.

28 Apr 2026

Ablation can lead to better outcomes for patients with advanced atrial fibrillation

A minimally invasive heart procedure may be a better first-line treatment than medication for people living with advanced forms of atrial fibrillation, according to a major international clinical trial led by researchers at the University of British Columbia.

27 Apr 2026

New cord blood approach boosts survival in blood disease patients

A new way of using umbilical cord blood for treating blood diseases could make the treatment more accessible to patients who need a stem cell transplant.

27 Apr 2026