Molecule News and Research

RSS

Eli Lilly, AstraZeneca begin AZD3293 Phase II/III study for treatment of early Alzheimer's disease

Eli Lilly and Company and AstraZeneca today announced enrollment of the first patient into AMARANTH, a Phase II/III study of an oral beta secretase cleaving enzyme (BACE) inhibitor currently in development as a potential treatment for Alzheimer's disease.

1 Dec 2014

CCR5 receptor plays key role in driving prostate cancer metastases

Although prostate cancer can be successfully treated in many men, when the disease metastasizes to the bone, it is eventually lethal. In a study published online December 1st in the journal Cancer Research, researchers show that the receptor CCR5 best known for its role in HIV therapy, may also be involved in driving the spread of prostate cancer to the bone.

1 Dec 2014

Researchers identify key molecule that drives excess protein production in Fragile X patients' brain

People affected by a common inherited form of autism could be helped by a drug that is being tested as a treatment for cancer.

27 Nov 2014

HIV drugs could be harnessed to treat leading cause of blindness

An established class of drugs, traditionally used to control HIV/AIDS infections, could soon be harnessed to treat the leading cause of blindness and visual impairment in the UK, for which currently there exists no cure.

27 Nov 2014

Researchers find unusual role of lactate in metabolism of alveolar soft part sarcoma

Researchers from Huntsman Cancer Institute at the University of Utah discovered the unusual role of lactate in the metabolism of alveolar soft part sarcoma (ASPS), a rare, aggressive cancer that primarily affects adolescents and young adults. The study also confirmed that a fusion gene is the cancer-causing agent in this disease.

27 Nov 2014

SLU researcher discovers way to block pain pathway

In research published in the medical journal Brain, Saint Louis University researcher Daniela Salvemini, Ph.D. and colleagues within SLU, the National Institutes of Health and other academic institutions have discovered a way to block a pain pathway in animal models of chronic neuropathic pain including pain caused by chemotherapeutic agents and bone cancer pain suggesting a promising new approach to pain relief.

27 Nov 2014

Antibiotic for infections comes from good bacteria found in turkeys

While the turkey you eat on Thursday will bring your stomach happiness and could probably kick-start an afternoon nap, it may also save your life one day.

26 Nov 2014

MACROD2 gene may explain why some breast cancers are resistant to tamoxifen

After mining the genetic records of thousands of breast cancer patients, researchers from the Johns Hopkins Kimmel Cancer Center have identified a gene whose presence may explain why some breast cancers are resistant to tamoxifen, a widely used hormone treatment generally used after surgery, radiation and other chemotherapy.

25 Nov 2014

Study: Selenium compounds appear to have beneficial effect on cancer

The immune system is designed to remove things not normally found in the body. Cells undergoing change, e.g. precursors of cancer cells, are therefore normally recognised and removed by the immune system. Unfortunately, the different cancer cells contain mechanisms that block the immune system's ability to recognise them, allowing them to freely continue cancer development.

25 Nov 2014

New approach to fighting breast, thyroid cancers

A team of researchers from the University of Alberta has discovered a new approach to fighting breast and thyroid cancers by targeting an enzyme they say is the culprit for the "vicious cycle" of tumour growth, spread and resistance to treatment.

24 Nov 2014

IBM, ASU scientists develop prototype DNA reader

A team of scientists from Arizona State University's Biodesign Institute and IBM's T.J. Watson Research Center have developed a prototype DNA reader that could make whole genome profiling an everyday practice in medicine.

24 Nov 2014

Researchers take major step in fight against sleeping sickness

Researchers from Aarhus University have taken an important step in the fight against sleeping sickness, a disease that is a major problem in parts of Africa. According to the World Health Organization, the disease threatens approximately 60 million people and the treatment options are poor.

24 Nov 2014

Researchers identify way to improve memory by manipulating molecule linked to Alzheimer's

In a new study conducted by the Sagol Department of Neurobiology at the University of Haifa and published recently in the Journal of Neuroscience, researchers report that they've found a way to improve memory by manipulating a specific molecule that is known to function poorly in old age and is closely linked to Alzheimer's disease.

23 Nov 2014

Researchers discover new method to deliver drugs into aggressive tumors

A multi-disciplinary team of Yale Cancer Center researchers has discovered a promising new method for delivering drugs into aggressive tumors by exploiting a unique feature of tumors themselves.

21 Nov 2014

Researchers identify genetic signatures in melanoma tumors that predict response to immunotherapy

A team led by Ludwig and Memorial Sloan Kettering (MSK) researchers has published a landmark study on the genetic basis of response to a powerful cancer therapy known as immune checkpoint blockade.

21 Nov 2014

Researchers uncover 'monstrous' hidden nature of molecule involved in prostate cancer

Researchers who have uncovered the 'monstrous' hidden nature of a molecule involved in prostate cancer say the findings could herald a new form of personalised medicine for patients, with doctors able to use the same molecular target for diagnosis and treatment.

20 Nov 2014

Special receptor signalling mediates astrocytic hyperactivity in Alzheimer's disease mouse model

It has long been known that astrocytes change their shapes as a consequence of Alzheimer's. Cells located near the "plaques", as the protein deposits typical for this disease are called, grow in size and form additional extensions.

20 Nov 2014

New nanoparticles can simultaneously perform MRI and fluorescent imaging in living animals

MIT chemists have developed new nanoparticles that can simultaneously perform magnetic resonance imaging (MRI) and fluorescent imaging in living animals. Such particles could help scientists to track specific molecules produced in the body, monitor a tumor's environment, or determine whether drugs have successfully reached their targets.

19 Nov 2014

Scientists find cells responsible for memory problems after sleep loss

Sleep is a critical period for memory consolidation, and most people don't get enough. Research has shown that even brief periods of sleep deprivation can lead to deficits in memory formation.

18 Nov 2014

Scientists identify how ADAR1 gene mutation can lead to diseases

Scientists have discovered how a gene mutation can lead to diseases that occur when the immune system attacks the body by mistake.

18 Nov 2014

Molecule News and Research

Eli Lilly, AstraZeneca begin AZD3293 Phase II/III study for treatment of early Alzheimer's disease

CCR5 receptor plays key role in driving prostate cancer metastases

Researchers identify key molecule that drives excess protein production in Fragile X patients' brain

HIV drugs could be harnessed to treat leading cause of blindness

Researchers find unusual role of lactate in metabolism of alveolar soft part sarcoma

SLU researcher discovers way to block pain pathway

Antibiotic for infections comes from good bacteria found in turkeys

MACROD2 gene may explain why some breast cancers are resistant to tamoxifen

Study: Selenium compounds appear to have beneficial effect on cancer

New approach to fighting breast, thyroid cancers

IBM, ASU scientists develop prototype DNA reader

Researchers take major step in fight against sleeping sickness

Researchers identify way to improve memory by manipulating molecule linked to Alzheimer's

Researchers discover new method to deliver drugs into aggressive tumors

Researchers identify genetic signatures in melanoma tumors that predict response to immunotherapy

Researchers uncover 'monstrous' hidden nature of molecule involved in prostate cancer

Special receptor signalling mediates astrocytic hyperactivity in Alzheimer's disease mouse model

New nanoparticles can simultaneously perform MRI and fluorescent imaging in living animals

Scientists find cells responsible for memory problems after sleep loss

Scientists identify how ADAR1 gene mutation can lead to diseases

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News