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Blood test can help match cancer patients to early phase clinical trials

Scientists could help match cancer patients with no other treatment options to clinical trials with experimental medicines, by analyzing the genetic faults in a sample of their blood, according to research published in Nature Medicine today (Monday).

23 Apr 2019

Researchers identify circulating proteins associated with progression of diabetic kidney disease

In a breakthrough study published today in Nature Medicine, researchers at Joslin Diabetes Center have identified a group of 17 circulating inflammatory proteins that are consistently associated with the development and progression of diabetic kidney disease.

23 Apr 2019

Treating cancer patients with personalized, combination therapies improves outcomes

Precision oncology often relies on treating patients with a single, molecularly matched therapy that targets one mutation in their tumor.

23 Apr 2019

Study identifies possible therapeutic effects of curcumin on stomach cancer

Curcumin is widely used to impart color and flavor to food, but scientists have discovered that this yellow powder derived from the roots of the turmeric plant (Curcuma longa) can also help prevent or combat stomach cancer.

22 Apr 2019

Advance in breakthrough cancer treatment eliminates serious side effects

An advance in the breakthrough cancer treatment known as CAR T-cell therapy appears to eliminate its severe side effects, making the treatment safer and potentially available in outpatient settings, a new USC study shows.

22 Apr 2019

Researchers are developing brand-new method to cure brain tumors

Scientists from Far Eastern Federal University in cooperation with colleagues from Blokhin Russian Cancer Research Center, Switzerland, and Sweden for the first time studied proteins, which constitute WNT signaling pathway of the cancer stem cells of glioblastoma multiforme (GBM CD133+ CSCs), one of the most aggressive brain tumors.

22 Apr 2019

Hole-forming protein could help control cancer growth

Sometimes cells need to die. The process of cell death is encoded within the genome of all higher organisms to kill off cancerous cells, and as a normal part of development to shape a mass of embryonic cells into the organism it will become.

22 Apr 2019

Precision-guided anticancer nanoparticles help enhance treatment of peritoneal tumors

Research carried out at the University of Tartu Faculty of Medicine used nanoparticles for the development of new imaging and treatment methods for peritoneal cancers. Tests showed that precision-guided anticancer nanoparticles have improved efficacy and reduced side effects.

22 Apr 2019

Potential of liquid biopsy in cancer biomarker detection and prenatal testing

The promise and challenges of liquid biopsy, an emerging, noninvasive method for targeted disease diagnosis and detection of cancer biomarkers to enable improved and personalized therapy, is the focus of a new special issue of Genetic Testing and Molecular Biomarkers, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

22 Apr 2019

Deep-learning model better predicts survival outcomes for lung cancer

A deep-learning model developed using serial image scans of tumors from patients with non-small cell lung cancer (NSCLC) predicted treatment response and survival outcomes better than standard clinical parameters.

22 Apr 2019

Molecular target UNC45A is essential for cancer cell proliferation and tumor growth

Identifying a protein that plays a key role in cancer cell growth is a first step toward the development of a targeted cancer therapy. It is especially promising when this protein is dispensable for the growth of normal cells.

19 Apr 2019

Scientists deploy CRISPR gene-editing tool to engineer multiple edits

Scientists at Christiana Care Health System's Gene Editing Institute and NovellusDx, an Israeli biotechnology company, have deployed a breakthrough CRISPR gene-editing tool to successfully engineer multiple edits simultaneously to fragments of DNA extracted from a human cell, according to a new study published today in The CRISPR Journal.

19 Apr 2019

Novel system enables researchers to study bacteria within mini-tissues in a dish

Engineering bacteria to intelligently sense and respond to disease states, from infections to cancer, has become a promising focus of synthetic biology.

19 Apr 2019

Triple negative breast cancer develop resistance to chemotherapy by turning on molecular pathway

Researchers at The University of Texas MD Anderson Cancer Center have discovered that triple negative breast cancer cells can develop resistance to frontline, or neoadjuvant, chemotherapy not by acquiring permanent adaptations, but rather transiently turning on molecular pathways that protect the cells.

19 Apr 2019

Tumor News and Research

Blood test can help match cancer patients to early phase clinical trials

Researchers identify circulating proteins associated with progression of diabetic kidney disease

Treating cancer patients with personalized, combination therapies improves outcomes

Study identifies possible therapeutic effects of curcumin on stomach cancer

Advance in breakthrough cancer treatment eliminates serious side effects

Researchers are developing brand-new method to cure brain tumors

Hole-forming protein could help control cancer growth

Precision-guided anticancer nanoparticles help enhance treatment of peritoneal tumors

Potential of liquid biopsy in cancer biomarker detection and prenatal testing

Deep-learning model better predicts survival outcomes for lung cancer

Molecular target UNC45A is essential for cancer cell proliferation and tumor growth

Scientists deploy CRISPR gene-editing tool to engineer multiple edits

Novel system enables researchers to study bacteria within mini-tissues in a dish

Triple negative breast cancer develop resistance to chemotherapy by turning on molecular pathway

HPV-negative cervical cancers are more aggressive with worse prognosis

Three studies show how tumors hijack the immune system to develop radiotherapy resistance

Innate immune sensor responding to gut microbes can suppress liver cancer

Geneva Exhibition committee gives gold medals to two medications developed by Kazan

‘PRO-cision Medicine’ approach helps personalize care for patients with cancer

Cancer cells grown in tumor-mimicking environment can help predict the effect of experimental drugs

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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