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Delirium in advanced cancer patients: an interview with Dr Knox Todd

Delirium is a terribly distressing syndrome of acute confusion. We often see it in the emergency department in older patients and in those with multiple medical problems. They may be acting strangely at home and concerned loved ones bring them to the emergency department.

7 Sep 2016

Heart specialists to examine benefit of ECG screening for student athletes

UT Southwestern Medical Center heart specialists will study whether electrocardiograms (ECGs) are useful in identifying Texas high school student athletes who are at risk of suffering sudden cardiac death.

7 Sep 2016

Experts recommend removal of restrictions in accessing new hepatitis C therapies for drug users

Global health experts are today are calling for the removal of restrictions preventing people who use drugs from accessing new hepatitis C cures. So long as these restrictions exist, the goal of disease elimination will remain out of reach, they say.

7 Sep 2016

Simple saline solution could help alleviate chronic nosebleeds, study shows

Squirting a simple saline solution into the nose twice a day could alleviate chronic nosebleeds just as effectively as spraying with any one of three different medications, reports a study published online in the Journal of the American Medical Association on Sept. 6.

7 Sep 2016

Studies examine effectiveness of nasal sprays in reducing frequency, duration of HHT-related epistaxis

Two studies appearing in the September 6 issue of JAMA examine the effectiveness of nasal sprays to reduce the frequency and duration of nosebleeds caused by hereditary hemorrhagic telangiectasia (HHT), an inherited condition characterized by abnormal blood vessels which are delicate and prone to bleeding.

6 Sep 2016

New drug holds potential for treating advanced mastocytosis

Most people have never heard of mastocytosis. It's a rare, sometimes deadly, immune disorder. Now new research may help those with advanced mastocytosis and possibly many more people, too.

6 Sep 2016

Dengue vaccine may worsen infections if used in areas with low rates of disease

The world's only licensed vaccine for dengue may worsen subsequent dengue infections if used in areas with low rates of dengue infection, suggests new research.

6 Sep 2016

Researchers identify potential new way of treating hypertension

Researchers eyeing first new anti-hypertensive drug treatment strategy in more than 15 years.

6 Sep 2016

Research findings pave way to better tailored treatment for oesophageal cancer

Scientists have discovered that oesophageal cancer can be classified into three different subtypes, paving the way for testing targeted treatments tailored to patients' disease for the first time.

6 Sep 2016

HIF-2 inhibitors could be promising target to combat kidney cancer

A new class of drugs called HIF-2 inhibitors is more effective and better tolerated than the standard of care drug sunitinib in treating kidney cancer, researchers with the Kidney Cancer Program at Harold C. Simmons Comprehensive Cancer Center have found.

6 Sep 2016

DNA-binding protein CHD1 could be potential biomarker for targeted prostate cancer treatment

The loss of CHD1, one of the most frequently mutated genes in prostate tumors, sensitizes human prostate cancer cells to different drugs, including PARP inhibitors.

5 Sep 2016

New study provides insights into how regulators support accelerated access to new therapies

It can be challenging for regulators to keep up with advances related to medical drugs and devices. A new analysis and editorial published in the British Journal of Clinical Pharmacology provide insights on how officials are working to support accelerated access to new therapies while also ensuring their safety.

2 Sep 2016

Meridian wins innovation award for illumigene Malaria test

Meridian Bioscience, Inc. was awarded 1st place for innovation in emergency treatment and point-of-care testing for its illumigene Malaria test at the 2016 JIB/ACNBH Conference this summer.

2 Sep 2016

Monoclonal antibody removes brain amyloid plaques in patients with Alzheimer's disease

Scientists at Neurimmune today described results from the Phase 1b PRIME clinical trial of the monoclonal antibody aducanumab.

1 Sep 2016

MedStar Heart & Vascular Institute offers bioresorbable stent for patients with clogged arteries

A heart stent that slowly dissolves into the body is now available for patients with clogged arteries.

31 Aug 2016

Surgically implanted neurostimulator system helps alleviate chronic pain

When the damaged nerves in Anthony Newberry's foot healed incorrectly after a workplace accident, it left him feeling "like my foot was exploding for hours at a time," he says.

30 Aug 2016

Nutrition could be cost-effective treatment to improve health in malnourished older adults

As a majority of older adults have two or more chronic conditions, finding new ways to improve their health and decrease the cost of care is vital to helping them live healthier, longer lives.

30 Aug 2016

New anticoagulant treatment safe and effective for AF patients before cardioversion

Patients with atrial fibrillation (AF) who need anticoagulation before undergoing electrical correction of their abnormal heartbeat (cardioversion) may benefit from treatment with edoxoban - a non-vitamin K antagonist (VKA) oral anticoagulant (NOAC), according to results of the ENSURE-AF trial.

30 Aug 2016

NCATS scientists identify promising compounds effective in inhibiting Zika virus replication

Researchers at the National Center for Advancing Translational Sciences recently identified compounds that potentially can be used to inhibit Zika virus replication and reduce its ability to kill brain cells.

29 Aug 2016

PCSK9 inhibitor can reduce need for apheresis treatment in patients with familial hypercholesterolemia

Patients who have heterozygous familial hypercholesterolemia (HeFH), a condition that causes abnormally raised low-density lipoprotein cholesterol (LDL-C) levels and premature cardiovascular disease, can significantly reduce or even eliminate their need for expensive and time-consuming apheresis treatments with the PCSK9 inhibitor alirocumab.

29 Aug 2016

Clinical Trial News and Research

Delirium in advanced cancer patients: an interview with Dr Knox Todd

Heart specialists to examine benefit of ECG screening for student athletes

Experts recommend removal of restrictions in accessing new hepatitis C therapies for drug users

Simple saline solution could help alleviate chronic nosebleeds, study shows

Studies examine effectiveness of nasal sprays in reducing frequency, duration of HHT-related epistaxis

New drug holds potential for treating advanced mastocytosis

Dengue vaccine may worsen infections if used in areas with low rates of disease

Researchers identify potential new way of treating hypertension

Research findings pave way to better tailored treatment for oesophageal cancer

HIF-2 inhibitors could be promising target to combat kidney cancer

DNA-binding protein CHD1 could be potential biomarker for targeted prostate cancer treatment

New study provides insights into how regulators support accelerated access to new therapies

Meridian wins innovation award for illumigene Malaria test

Monoclonal antibody removes brain amyloid plaques in patients with Alzheimer's disease

MedStar Heart & Vascular Institute offers bioresorbable stent for patients with clogged arteries

Surgically implanted neurostimulator system helps alleviate chronic pain

Nutrition could be cost-effective treatment to improve health in malnourished older adults

New anticoagulant treatment safe and effective for AF patients before cardioversion

NCATS scientists identify promising compounds effective in inhibiting Zika virus replication

PCSK9 inhibitor can reduce need for apheresis treatment in patients with familial hypercholesterolemia

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