Efficacy News and Research

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Article calls for international governance system to oversee access to Covid-19 vaccines, treatments

Human challenge trials to test the efficacy of vaccine candidates against SARS? CoV? 2, the novel coronavirus behind COVID? 19, could save considerable time and many lives.

11 Jun 2020

A lead compound can significantly reduce or eliminate toxoplasmosis and malaria

Toxoplasma gondii infection is one of the most frequent parasitic infections of humans. This parasite is present in the brain of an estimated two billion people--about 40 percent of all humans on earth. It is endemic throughout the world, causing water and food-borne epidemics that result in toxoplasmosis.

10 Jun 2020

Study investigates potential of adoptive cell therapy in combination with checkpoint inhibitors

Volume 11, Issue 22 of @Oncotarget reported that there are rationale and evidence supporting immune therapy in Ovarian Cancers.

10 Jun 2020

Researchers evaluate survivin expression in neuroendocrine tumors

Volume 11, Issue 23 of @Oncotarget reported that tissue microarrays of 132 patients were stained for survivin using immunohistochemistry and correlated with outcomes.

10 Jun 2020

The 2019 3Rs prize awarded to two pieces of novel research

The 2019 3Rs prize has been jointly awarded to Dr Francesca Nunn and Dr Marta Shahbazi for papers describing research that reduces the number of chickens and mice respectively. The 3Rs prize is awarded by the NC3Rs and sponsored by GSK.

10 Jun 2020

Study shows safety of new cell therapy approaches for kidney transplant recipients

A large international study coordinated by University Hospital Regensburg and Charité - Universitätsmedizin Berlin has demonstrated the safety of new cell therapy approaches for use in kidney transplant recipients.

10 Jun 2020

3D printing technology can inhibit the proliferation of cancer cells in vitro

Doctors could soon be administering an entire course of treatment for life-threatening conditions with a 3D printed capsule controlled by magnetic fields thanks to advances made by the University of Sussex researchers.

10 Jun 2020

Weighing the risks and benefits of drug screening

Little evidence supports the new recommendations for clinical screening for drug use. Do the potential benefits outweigh the potential harms?

10 Jun 2020

Deployment of health care professionals can improve inflammatory-rheumatic disorders

Inflammatory-rheumatic disorders are a widespread ailment, affecting at least 1.5 million people in Germany alone.

10 Jun 2020

Deep UV LED inactivation of SARS-CoV-2 - fast and effective

The ongoing pandemic has aroused considerable effort to find methods to prevent and control the spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes COVID-19 disease. Rapid inactivation devices would be of great help in this area, to prevent viral transmission through aerosols and contact with infected surfaces.

9 Jun 2020

Unique mutations could weaken Indian SARS-CoV-2 strain

A new study published on the preprint server bioRxiv in June 2020 suggests that the presence of unique mutations in the viral strains circulating in India has led to their attenuation.

9 Jun 2020

Cannabis temporarily reduces severity of PTSD symptoms

People suffering from post-traumatic distress disorder report that cannabis reduces the severity of their symptoms by more than half, at least in the short term, according to a recent study led by Carrie Cuttler, a Washington State University assistant professor of psychology.

9 Jun 2020

Probiotics are not recommended for most digestive conditions

It is estimated that more than 3.9 million American adults have taken some form of probiotics, with many patients looking to probiotics to improve their gastrointestinal health.

9 Jun 2020

Old antibiotic may be a powerful new tool against deadly superbug

USC researchers have discovered that an old antibiotic may be a powerful new tool against a deadly superbug, thanks to an innovative screening method that better mimics conditions inside the human body.

8 Jun 2020

Novel compound shows promise for ANCA-associated vasculitis

ANCA-associated vasculitis (AAV) is a systemic disease involving the formation of special autoantibodies (so-called anti-neutrophil cytoplasmic antibodies/ANCA) and vascular inflammation.

8 Jun 2020

Using antibodies to detect Alzheimer’s disease

News-Medical speaks to Professor Vendruscolo about his research that uses antibodies to detect Alzheimer's disease, which could help to improve drug discovery.

8 Jun 2020

Tocilizumab in COVID-19 patients on mechanical ventilation

Now, a new study by researchers from the University of Michigan and published on the online preprint server medRxiv* in June 2020 shows that the cytokine inhibitor tocilizumab could have a favorable effect on survival in the most severely infected patients who require mechanical ventilation. This needs to be confirmed by clinical trials.

7 Jun 2020

New strategy may facilitate development of multi-epitope peptide vaccine against SARS-CoV-2

By combining T and B lymphocyte analysis with manufacturability heuristic, researchers from the US and Germany proposed a set of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine peptides to use in subsequent animal studies and clinical trials. Their paper is currently available on the bioRxiv preprint server.

7 Jun 2020

Approved drug could help dampen massive immune response associated with severe COVID-19

The drug acalabrutinib, FDA-approved for the treatment of several types of B cell cancers, improved the oxygenation levels and decreased molecular markers of inflammation in a majority of 19 patients hospitalized for the treatment of severe COVID-19, according to a new study by Mark Roschewski and colleagues.

5 Jun 2020

Volcanic glass spray effective in controlling mosquitoes

An indoor residual spray made by combining a type of volcanic glass with water showed effective control of mosquitoes that carry malaria, according to a new study.

5 Jun 2020